Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60468	Thiostrepton	GSE92742	SKB	Human	24h	10uM	EID0341

Response Information :

Types	Number	Response transcription factors
Up-regulation	135	HOXA5; ZNF473; MSX1; ZNF410; CEBPA; CIR1; DDIT3; ZNF212; BAZ1A; MED6; HOXB2; TCF7; KLF7; MAFG; ATF4; BTF3; SNW1; ZNF394; GABPB1; CCNT1; DPF2; ZNF222; MECOM; ZNF430; RYBP; PCGF1; SAP130; SF1; TBP; ELF4; SFPQ; CDK7; ZNF426; ZNF263; COPS2; ESRRG; TSC22D2; ZNF140; PPRC1; FOXJ3; TRIP4; CCDC59; HOXD10; JUN; TLE1; HLX; ZNF10; TAF5; DNAJC2; SALL1; BATF; ZNF304; RUNX3; ZNF91; SIX2; PIR; ZNF557; PIAS4; HOXD11; CNOT2; MEN1; ATF3; KAT6B; SERTAD2; IRF1; ZNF195; ZKSCAN1; CTR9; NFYC; SMAD7; HOXB6; ZNF3; KDM2A; ZNF200; ISL1; ZNF652; TP63; HIVEP2; ZNF44; ZFHX3; KAT6A; EN1; HOXA1; WT1; ZNF136; KLF10; PA2G4; CD3D; AFF1; ZNF544; ZNF573; ZNF165; YWHAB; KLF13; BRPF1; BRD2; PIAS1; ZNF12; COPS5; RBBP5; RBPJ; RNF10; REL; BTG1; RBM14; ZNF281; BRD4; MNDA; NFIC; CSDE1; MED24; MXI1; RORA; NFATC1; PHIP; ZBTB11; ATF7IP; CARM1; FOS; SIRT7; MTA1; FOXD1; CALR; ZNF423; BHLHE41; LEF1; MEIS2; FOSL1; IRF8; MNAT1; ETS1; ARID5B; NFAT5; POU2AF1; MTF2
Down-regulation	88	ATF1; ERBB2; USP22; TSC22D3; WWC1; HIF1A; SCAND1; ENY2; LIN28A; SPDEF; ZMIZ2; NCOR1; UBP1; TEAD4; AES; NFYB; RNF141; HSBP1; NR2C1; DNMT3B; LMCD1; CCNA2; HLF; WWTR1; ZMYND11; NANOG; RBFOX2; TCF3; KLF2; MEF2C; CARHSP1; ITGB3BP; CBX3; PRMT2; CBX5; HMGB3; MED7; CREBL2; CBFB; TP53; PBX1; PMS1; SOX10; ZEB2; TGFB1I1; TRIM22; TRIM16; NRIP1; MYCBP; SMAD3; HDAC9; AEBP1; STAT1; RBPMS; NFE2L3; FLNA; HOXA10; HMGB2; CBX7; SATB2; ZFPM2; ZNF532; TXNIP; FOXN3; ZFP36L1; PTTG1; KAT2B; ZNF226; HLTF; ERBB4; CEBPD; HDAC6; ID4; ETS2; ELF3; PLAGL1; RUNX1; SOX4; ZSCAN18; AHR; CTBP2; MAGED1; NR1H2; SSBP2; SPEN; NR2F1; MYBL1; ZIC1