Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60433	Tak-715	GSE92742	SKB	Human	24h	10uM	EID0341

Response Information :

Types	Number	Response transcription factors
Up-regulation	374	IKZF1; E2F2; SATB1; PPARG; PAX8; CREB1; TBX2; DAXX; GATA2; ZNF586; AFF1; TBP; ZNF189; FOXJ3; ZNF711; ZNF177; RBL1; NKX2-2; BRCA2; BLM; TCF15; KLF2; POLR3F; ZNF292; NR0B1; NR3C2; USF2; DBP; CARHSP1; GFI1; ZNF696; CEBPE; YAF2; FHL5; ZNF510; ING3; ZNF764; TAF7L; LYL1; SSX3; ZNF236; HOXA5; ZNF140; ZNF493; PPARGC1A; CBL; TLX2; MZF1; FLI1; MAP3K10; ZNF32; KMT2D; IRF5; ZSCAN16; AGO2; BCL11B; NKX2-8; ZEB2; NPAT; ZNF212; BRWD1; HAND2; MEF2A; ZNF8; SRY; OVOL1; ZNF124; CIR1; YBX2; PRRX1; HOXC6; NEUROG1; EGR1; ZNF446; MLXIP; ZNF143; ZNF770; TCF7; NFRKB; HOXD13; ZNF174; MYT1L; WHSC1; CEBPA; MAPK8IP1; CREBZF; EN2; MEOX2; FOXD2; KDM4A; EGR4; MXD3; TCFL5; BACH1; PML; SPIB; MDM4; SIX5; TMF1; MLLT10; TXNIP; HMX1; WWP1; KMT2A; LHX6; NFX1; CAPN15; EGR2; POU3F1; HEY2; POU2F2; EGR3; ZNF556; THAP9; ZMIZ2; EVX1; LHX1; ETV6; MBD1; BPTF; JUNB; PRDM8; FOXJ1; BAZ2A; TRIM32; ZNF423; RCOR1; ZNF34; ZNF250; ARRB1; E2F3; ZNF248; ZBTB43; DDX5; ZNF551; ZNF516; IKZF4; SETD3; HR; PRDM12; MSX1; SIX6; CHD1; CHAF1B; HOXC4; ZNF682; SNAI1; ZFP2; ZNF473; ZKSCAN3; CIC; ORC2; HDAC4; ANKRD1; TFAP2B; NLK; KLF10; NPAS1; SMAD4; FOXN3; HOXA3; EBF2; EP400; NR1D2; GABPA; NR6A1; EP300; ZSCAN12; RFX7; POU3F2; ZNF223; ZNF646; ZNF93; ZNF506; ZBTB20; CCNT1; ZNF721; CDX2; HNF1A; UBE3A; ZBTB25; HOXB13; NEUROD6; TSC22D4; NKX2-5; POU3F3; DYRK1B; PIAS1; NUP62; ZNF667; ZNF276; HLF; ZNF500; MAX; ZNF219; WDHD1; HSF1; ARID4A; BRIP1; GLI1; GCFC2; MED1; HEYL; JAK2; ZNF354A; ZSCAN5A; CRTC1; NR5A2; ZBTB6; ZNF227; POU4F2; EHMT1; POU4F1; SMAD6; ZNF573; ZNF165; RXRG; CAMTA1; PAX7; ZSCAN18; CARF; NRL; AEBP1; NFATC1; SOX15; STAT6; BIRC2; NR5A1; JUP; MAZ; HDAC11; ZNF7; ELK3; ZNF84; TBX3; PIAS2; KMT2B; AIRE; IRF1; FEV; MEOX1; MYT1; HDAC7; VAX2; HESX1; ZNF135; KLF4; RNF14; E2F1; PBRM1; KLF12; FOXN1; DNMT3B; HOXA1; TAF4; ONECUT2; NFKBIB; KDM2A; SOX12; SFMBT1; POU3F4; MAK; BLZF1; DDIT3; KLF11; ZNF23; ZNF329; SF1; ZNF813; BRD3; ZNF254; SOX21; ZNF665; WWTR1; TLE1; ZNF536; LPIN2; HOXD10; ZNF44; SFPQ; ZBTB44; SOX11; SALL1; NRBF2; NFIB; KDM5C; IL16; ZNF672; SMAD9; PHOX2B; PNRC1; SIM1; MNDA; E2F5; SMAD3; SMAD2; MTF2; BBX; ZFX; ZNF202; ZNF253; PSMC3IP; HOXD3; REPIN1; HSF2; RBBP5; GATA6; ELF2; WT1; ZNF443; ID4; POU2F1; PRDM1; MED6; KLF6; CERS4; NEUROD1; ID3; FLNA; NR1H3; CDX1; HCFC2; MAGED1; TOPORS; LEF1; SCAND1; ZNF160; FOXE1; SPI1; TAL1; ARNTL2; ZSCAN31; SMAD7; UBE2L3; TFEC; TAF10; FOS; GLI2; PRRX2; ZNF211; NKX2-1; FOXI1; ARID4B; EMX2; ELF5; BRPF1; IRX5; ZNF239; KDM5A; ERG; ZBTB11; TDP2; TFAP2C; ZNF217; CNBP; ZNF184; ZBTB7A; KLF9; ELF1; GRHL2; CITED2; TGIF1; MYB; BRD2; SATB2; ASCL1; PAWR; MTA1; SMAD1; SPEN; MEF2C; IRF6; TOX3; NFATC3
Down-regulation	393	PUF60; LOXL2; CEBPB; ATF5; TSC22D3; SSRP1; HEY1; FHL2; HMG20B; RHOA; NFE2L2; SUMO1; GTF2A2; PMF1; ILF2; PARP1; USP21; RBFOX2; MYC; GTF2F1; ABT1; HDAC2; HOXB6; PBX1; DNMT1; TSC22D1; RFXANK; GMNN; TFDP1; SNAI2; CTNNB1; COPS2; TCF25; HDGF; PIR; CHD8; KAT2A; PIAS3; COPS5; YBX3; MYRF; HIF3A; SAFB2; PRPF6; PPARD; SMARCC1; CNOT2; RYBP; APEX1; BTF3; SMARCA5; YBX1; DRAP1; PSMC3; RAN; EWSR1; ITGB3BP; CREB3; FOXG1; BNC2; PCBD1; ARHGAP35; RUVBL2; SIX2; XBP1; MED21; CERS6; IFI16; PCGF1; ZNF274; C1QBP; MITF; TCF7L1; TCEA2; MED16; GTF2A1; SREBF1; HMGXB4; HOXB2; SUPT6H; RUNX3; ARID1A; BRD7; RBPJ; CDC5L; HOXB5; TRIM16; MDM2; ERCC3; WWC1; GTF2IRD1; CSDE1; NFE2L1; ZNF593; SOX13; HIPK2; KAT5; HMGB1; RELA; TRIP6; XRCC6; ZBED1; RBM39; VPS72; NCOR1; NPM1; MEIS2; DEK; MLX; ENY2; TCF12; TAF9; ZBTB17; FOXA1; SNW1; ATN1; NACA; ZNF692; SUZ12; PQBP1; ZNF35; SP3; ZNF816; CEBPZ; AIP; CBX5; TCEA1; IRF9; TAF7; LDB1; NFIX; NKRF; ATF6; CBFB; PPP1R13L; CCNH; ZNF331; KAT6A; HDAC1; AES; ATF2; ZNF576; HLX; CLOCK; DPF2; SMARCD3; SUPT5H; RBBP7; ADRB2; HMGN3; HSBP1; CCDC59; CDK7; TGS1; GMEB2; POLR3C; CTR9; HDAC5; PFDN5; GABPB1; NCOA3; FOXO3; ADNP; CBFA2T2; NR1H4; ELK1; FOSB; PRDM2; PEX14; SPDEF; YAP1; NAB1; ZBTB16; MTDH; POU5F1B; TULP4; SAFB; TRAK1; CTBP1; SSBP2; CDK9; BACH2; NR2C1; AR; TCERG1; ZBTB18; NHLH2; SOX9; TADA3; TAF6; ZNF337; HIVEP1; ZNF580; RERE; HOXB3; TBX1; ENO1; PRKDC; RAD21; TBPL1; NR3C1; SMARCA1; FOXK2; PREB; FEZF2; PLAGL1; HDAC9; ZNF415; THRB; TSC22D2; SHOX2; NPAS2; RARB; SP140L; MTF1; TRIM29; SAP18; BCL11A; SOX17; SUPT3H; GLI3; KAT2B; TP53; ERCC2; NONO; ZNF532; ZIC1; RSF1; PBX3; ZNF574; ZEB1; NOC2L; TTF2; HIC2; EYA1; ETS1; NFKBIA; BRF2; PPRC1; NEDD8; THAP1; ZNF91; CARM1; PHIP; PKNOX2; ZNF652; IRF2; MEF2D; TSG101; ZNF266; TFAP2A; MYBBP1A; DDX17; SP100; TSHZ2; ZHX3; RELB; NCOR2; NKX3-1; USP16; THRA; SETDB1; SREBF2; ID1; EHMT2; CUX2; TWIST1; E2F6; PLAG1; FOXM1; TRRAP; MED24; RARG; CNOT6; HLTF; HDAC3; SMARCB1; RING1; SUPT4H1; RBBP4; FOSL2; KLF7; KAT6B; LMCD1; ZNF33B; IRF7; SKIL; ZNF12; RORC; HMGXB3; FOXD1; CALCOCO1; PTTG1; BCL6; DMTF1; TRIM28; ZNF146; DNAJC2; BASP1; ZZZ3; NELFB; RB1; TRIM27; SMARCA4; FOXF2; MYCBP; BAZ1B; RBBP8; STAT3; TEAD1; KAT8; BARX1; CBFA2T3; VGLL4; WIZ; NFIL3; ZNF195; RARA; JUN; HMBOX1; ZBED2; EHF; FOXO1; MAFF; TEAD4; THAP7; HDAC6; TP63; ZNF302; TCF3; PITX1; ZFHX4; CCNE1; CBX6; HOXB7; BRD8; CDK2; SOX4; ATF3; LZTR1; ST18; NR4A3; NR2F6; ZIC3; THAP10; SETD2; MNAT1; TLE2; CALR; ETS2; TOX4; HHEX; ZBTB1; BHLHE41; RNF4; MECOM; CDK8; ZNF45; SUB1; PEX2; NFIC; STAT1; RNF10; FOXF1; NCOA2; ZFP36L1; TFAM; SOX2; ZKSCAN1; PTRF; ERBB4; ZNF512B; TBL1X; CUX1; ZNF281; ZBTB38; BCL3; ZNF232; BRD4; URI1; SP110; TCEB2; RUNX1; IRF4; KDM5D; MXI1; MAF; BMI1; IRF8; ELF3; FOSL1; THAP11; NFATC4