Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60396	Bosutinib	GSE92742	SKB	Human	24h	10uM	EID0340

Response Information :

Types	Number	Response transcription factors
Up-regulation	136	HDAC9; TSC22D3; BHLHE41; ZNF217; RFC1; GRHL2; ACTL6A; ARRB1; ZNF93; TAF4; MNAT1; ATF5; ZNF253; ZSCAN16; SSBP3; ZNF85; ZBTB39; CBFA2T2; IRF9; KDM5C; ZNF500; SUMO1; E2F6; ING4; ZNF107; TAF4B; ZNF195; TTF2; PIAS4; ATN1; STAT3; TFCP2; ZNF273; E2F8; TRPS1; SUZ12; ZNF654; MYBL2; TP63; YEATS4; LYL1; ANKRD1; TRIM24; OVOL2; VPS72; ZSCAN31; PHIP; RAD21; PCGF1; NKX2-1; MYB; ZBTB44; KAT6B; HMGB3; ZNF117; ZKSCAN1; ZNF552; BNC1; CALR; ZNF33B; PBX3; EHF; MYCN; TTF1; CCNH; VEZF1; FOXE1; IRF7; MXI1; ATF3; MEIS1; NFATC4; KLF10; HHEX; MLXIP; ZBED2; HTATIP2; TCF12; ZBED1; NFYB; ZNF665; NFE2; BRIP1; RUNX1; SERTAD2; MECP2; URI1; ETV5; RNF141; IRF6; NFE2L1; LIN28A; FOXK2; ZNF430; NFIB; SPDEF; SETDB1; DMTF1; ARNTL; PBXIP1; CUX2; CTBP2; TOX; ST18; ERBB4; TGFB1; NKX3-1; DACH1; TFAP2A; TOB1; TFAP2C; PAX6; ZFP36L2; CBX3; IFI16; GATA6; KLF11; ELF3; SAP30; ZNF589; ZNF423; TLE1; ERG; MAFB; ZNF331; POU2AF1; ASCL1; ZMIZ1; AEBP1; PIR; ELK3; CREG1; ZNF91; TXNIP; RFX5; TCEA2
Down-regulation	115	ZMYM2; LOXL2; ETS1; ZEB2; CDK8; MAGED1; MED24; RNF4; CBX5; TAF9; IKBKAP; PBX2; ZNF529; TCF25; APEX1; TLE4; DDX17; HIRA; DRAP1; PUF60; GATAD2A; SCAND1; KAT8; MYT1; ERBB2; CREB5; HEY2; MNT; RBM14; CBFB; SIX2; TP53; MYC; CDYL; SAP18; PBX1; NR0B1; FOSL2; EBF2; SALL1; CNOT2; CREM; ARID4B; USF2; PITX2; AFF4; FOSL1; PSIP1; CAPN15; EYA1; ZEB1; C1QBP; GTF3A; DNMT1; TCEB2; RUVBL2; SMARCA4; KLF2; NFKB1; CREB3L1; RUNX3; BRD8; USP22; JARID2; HOXA5; BTF3; KDM5D; BASP1; BAZ1A; NAB1; TOX3; HIPK1; CHD1; MBD2; PATZ1; BAZ2B; CITED1; NCOA4; PLAGL1; MED23; PEG3; FOXD1; TBL1X; BCL3; NKX2-2; ZBTB38; RLF; HLF; IRF8; NR2F2; FLNA; ZNF274; MNDA; TCF4; JUNB; SFPQ; MSX1; MYBL1; PTTG1; FOXO1; EGR3; MTA1; SATB2; FHL2; OLIG2; TSC22D2; SMAD3; INSM1; ZBTB18; EMX2; EZH2; NR4A2; CREB3L2; LEF1; HOXC6