Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60328	Celastrol	GSE92742	SKB	Human	24h	10uM	EID0340

Response Information :

Types	Number	Response transcription factors
Up-regulation	174	SATB1; PLAGL2; SSBP3; ACTL6B; ZSCAN32; SMARCD1; SP3; NFKB2; HHEX; BRPF1; LHX1; GATA2; NEUROG1; RNF10; RNF4; EP300; TRIM32; AES; ZNF217; ESRRG; NEUROD1; ATF5; DAXX; CCNE1; IRX5; E2F6; TFE3; NELFB; PRDM1; NR0B2; PCGF1; NHLH1; HDAC11; CTNNB1; ZNF253; ZNF586; TLE2; HDAC1; RREB1; SOX17; TAF5; HNRNPD; BHLHE40; IRF1; ZNF408; MAML1; SERTAD2; MED16; MEIS1; NHLH2; TEAD3; BLM; ZNF443; CNBP; ZNF93; RBBP8; CIZ1; MYT1L; AEBP1; TRIM24; MED27; ZNF468; ABT1; INSR; NEUROD6; CHD1; SALL1; HMGN3; TFCP2L1; ELF1; PAX6; MDM2; FOXM1; ZNF423; HMG20B; ELF3; CBX7; TADA3; TSC22D2; RBL2; FOXC1; PPARGC1A; SNIP1; KLF3; CHD3; RB1; FEV; NFATC1; DLX4; POU5F1B; TBL1X; MXD1; ZNF14; ZNF510; PROX1; AGO2; SHOX2; NKX3-1; PCGF3; NR0B1; TRRAP; JUP; CBX3; NFIC; TGFB1; PRDM2; EN2; HMGA2; BRCA1; TCEB2; ZBTB16; CTBP1; ETV4; HDAC3; AFF1; ARID4A; CAMTA1; RUVBL2; VEZF1; SIAH2; CITED2; URI1; DNAJC2; CUX2; RNF138; CBFA2T3; YBX1; ZNF91; ELF5; GABPB1; CDK9; ZNF587; PIR; OSR2; ZNF160; SATB2; MGA; RCOR1; TXNIP; JUN; ZFHX3; MSX1; ZNF189; ESR1; ETS2; HSBP1; NKX2-2; MLXIP; YWHAB; HOXD3; PEG3; ZNF711; ZIC1; FOSL1; ENO1; HLX; DNMT3B; SMARCA1; SMAD4; KLF2; DLX5; BCL11B; NFE2L3; SPEN; NFIB; MECOM; NPAS2; SAP30; EHF; ZNF331; FOXN3; ERBB4; NR2F2; NFE2L2
Down-regulation	159	DNMT1; CERS6; EED; BHLHE41; ZNF22; ASH2L; COPS5; ELF4; TFAM; TFCP2; CIR1; VDR; ZNF544; PDLIM1; IRF7; ARRB1; MSC; CHD8; TBX3; ID3; APEX1; ZNF135; CCNA2; PRKDC; BIRC2; TAF1; IRF8; YAP1; ZNF692; NFE2; ATF2; SP2; RSF1; ARHGAP35; NR1H3; KAT2A; ZNF195; ZNF32; TERF2; KDM5B; PITX2; ZNF10; MED14; BRD8; FOS; HDAC9; TSG101; USP16; UBE2L3; WIZ; SIRT7; MLLT10; HCFC2; SETDB1; NCOA2; RYBP; SPIB; CCNC; ZMYND11; BPTF; SP100; ASCL1; ILF2; HDAC6; PMS1; PSIP1; PATZ1; ZNF226; NCOA4; MITF; NUP62; SP110; MTDH; TLE4; HIPK2; RBBP7; PBXIP1; ZBTB20; CITED1; NPAT; FOXD1; PKNOX2; VPS72; PBRM1; ZNF589; SALL2; MXI1; TBL1XR1; HOXB7; SMAD6; TCEA1; HOXB2; HDAC4; ZNF302; ZHX2; ATF3; MNT; DNAJC1; SF1; TDP2; TAF10; SREBF1; CHD4; ACTL6A; LEF1; FOXG1; POU2AF1; GATA6; TULP3; LIMD1; GMNN; PEX2; ZNF274; TSC22D1; BTG1; PHF20; ETV1; HOXA5; MYRF; SPDEF; TOX; ING3; TCF4; MYB; ZNF432; ZSCAN18; ZBED2; ZNF264; FOSB; SETD2; MAFF; MED1; HOXB6; SMAD2; NFATC3; ZKSCAN1; KLF10; TFAP2C; CDK2; MEIS2; NFKBIA; HEY1; MKL2; RNF6; FHL2; MAGED1; NRIP1; SMAD3; TRPS1; TCF21; ID2; BAZ1A; PCGF2; PBX3; SMARCA2; BMI1; EGR1; RELB; BASP1