Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60327	Withaferin-a	GSE92742	SKB	Human	24h	10uM	EID0340

Response Information :

Types	Number	Response transcription factors
Up-regulation	349	ADRB2; ZKSCAN3; HOXC11; SHOX; NR3C2; NR3C1; SSBP3; APBB1; PAX8; ZNF76; PBX2; CIC; HIVEP3; CRYM; TBX3; CBX4; ZNF646; SMARCD1; TFAP4; BARX1; TEAD3; GATA2; ZNF467; ZNF335; ZNF276; ZNF443; ASH1L; POU6F1; NKRF; ETV7; ETV1; PLAGL2; KLF2; TSC22D4; AGO2; PHF1; MEOX1; PROX1; FOS; ATF3; PROP1; HABP4; HDAC11; RORC; NR4A1; NEUROD6; CREM; HR; ZFHX4; ARID5A; MYOG; CDX2; BCL3; MNX1; GTF2IRD1; SNAI1; ATF6; SSX3; SPIB; HMX1; HOXC10; E2F2; KDM5A; AFF4; ZNF384; MTF2; RELA; RFX5; THAP11; JUNB; ELF3; EYA3; FOXF1; MSC; MLXIPL; NKX6-1; SOX9; HMGXB3; MAP3K10; IKZF2; STAT5B; MYB; PRDM5; NR6A1; HMGA1; NOCT; SNIP1; CIR1; MEF2D; NR1H3; FOXO4; RELB; CALCOCO1; PBXIP1; ZNF574; FOXN1; GLI1; TSHZ2; TCF7; ZNF253; ZNF239; BRD4; THRB; MLLT10; ETS2; ZBTB43; CBX5; TCF15; IKZF4; GLI3; ONECUT1; HDAC6; KLF12; ESRRA; SHOX2; PAX9; MXD3; TAF1C; KAT7; TCF20; HOXA3; PRDM1; BAZ2B; FOXJ2; GON4L; FOXE1; MYC; TRAF6; BCL11B; TLX1; KLF15; ATF7IP; ZSCAN2; HOXC4; HNF1B; NHLH1; TBX4; DAXX; GFI1; HOXB3; HOXD9; NAB2; KLF3; CRTC1; CREB3L1; AES; PNRC1; SATB2; PRMT2; SLC2A4RG; ZNF552; HOXB13; MNAT1; SFMBT1; RXRB; SOX12; NKX3-2; ZMIZ2; HAND2; ETV6; HDGF; HIVEP1; TAF1; ZNF331; SUMO1; KDM4A; NFYC; CHD3; HOXD13; CBX7; PITX1; HOXD3; KDM5C; PITX3; HOXD1; EP300; EP400; ZBTB7B; ZNF507; TRIM25; NKX3-1; RAX; SPI1; DBP; MBD3; EGR3; THRA; FOSB; NR1H2; ZNF148; DDIT3; CHD2; RORA; RHOA; BHLHE40; HLF; MAZ; JUND; ZNF423; ARID3B; LHX1; ZNF446; ASXL1; HSF4; SALL2; CREBZF; ARID5B; ZNF787; PRDM14; WHSC1; TGFB1I1; RFX2; NFAT5; HMGN3; GBX1; TFDP2; JUP; YBX2; BTG1; ZBTB18; KMT2D; ZNF671; ZBTB40; NFKB1; MEN1; HMGB1; RING1; NR1I3; NRF1; MXD1; ZSCAN16; BANP; CD3D; CHD4; PHOX2B; TP53; DMTF1; SSX1; IKZF5; ARNTL2; ZNF212; CEBPE; ZNF444; ESRRG; PRRX2; SUPT6H; ZBTB14; ZNF516; MTA1; IRX5; ZNF510; MAFF; KAT5; ZNF536; ZNF835; ARID4A; MZF1; CAMTA1; STAT2; FEV; ERF; BBX; TOX4; AFF1; KDM2A; FOSL2; USP21; MDM2; IRF7; RARB; MYRF; ERBB2; MEOX2; NFE2L3; CAMTA2; CREB1; IRF6; NFIC; SREBF2; ZNF85; FOXJ1; RBL1; ZNF175; NR4A3; LHX3; KDM4C; CBFA2T2; NPAS2; OLIG2; TWIST1; ZNF93; AIP; LPIN2; SF1; HDAC4; TFCP2L1; NFATC1; CEBPA; WNT4; ZNF281; ETV4; HLTF; ELF1; SMAD7; USF2; HOXA1; KMT2A; PKNOX2; MLXIP; TERF2; SOX5; ZNF267; TFEB; HMGB2; EYA2; ING3; BRD2; TLE2; MNT; FOXA2; SPDEF; KLF13; MEIS2; ARNTL; SMARCA2; ERBB4; NKX2-2; CALR; CITED2; ABL1; MAGED1; MKL2; SIAH2; MED1; KLF4; MAFB; ZNF580; NR4A2; TSC22D1; HOXC6; BRCA1; LEF1; POU2AF1; PEG3; SOX11; KLF9; ESR1; TXNIP; VGLL4
Down-regulation	321	YBX3; HEY2; AHR; SNAI2; SMARCD2; CCNC; HIF1A; ZNF83; CDYL; MMS19; TCEA1; FOXO3; ZFP36L2; ATF5; FLI1; PTRF; KDM5B; APEX1; PMS1; RUNX1; KAT6A; NR2F6; PARP1; SMARCC1; BHLHE41; COPS2; PREB; IKBKAP; RNF14; ZNF146; NR2C1; TFDP1; ZNF426; YEATS2; TAF1A; UBE2I; TBX2; TSG101; MED13; ZNF32; NFYB; XRCC6; ZNF529; THAP1; UBE3A; ZNF302; PRKDC; STAT1; CBFB; SUPT7L; ZNF12; ZNF573; FOXO1; TCF7L1; KAT8; ZNF268; PSMD9; HDAC2; SNW1; ILF2; HTATIP2; COPS5; NFKBIB; GFI1B; PRPF6; POU2F1; CEBPG; CDC5L; ZNF688; RNF4; ZNF224; USP22; ZNF232; WWTR1; TCEB2; ZNF675; VGLL1; MTDH; ITGB3BP; IFI16; SREBF1; REXO4; CEBPZ; ZNF337; BRD7; CREB3; TBP; GCFC2; CSDE1; ZNF652; HDAC3; ZEB1; PSMC3; NCOR1; NCOA4; CEBPD; ZNF468; CNOT2; MXI1; PHF20; BIRC2; ECD; HDAC9; HOXB7; TSC22D3; ZMYM2; CBX3; HIRA; TBL1XR1; E2F5; PBX3; ZNF532; CBFA2T3; CDK8; ENO1; MYCBP; PAXBP1; MED23; TLE1; NFKBIA; CLOCK; TULP3; RBBP4; VPS72; HOXB6; PUF60; NUP62; HOXB9; ETS1; CARHSP1; TBX1; ASH2L; MED20; NFATC4; CCNA2; EMX2; PIAS3; NHLH2; PSIP1; TFCP2; ZBTB16; ZBTB7A; ZNF112; WDR77; ZNF512B; ZMYND8; CHD9; MBD4; HNRNPD; ENY2; AEBP1; BCOR; PCGF1; HLX; TAF12; ATF4; FUBP1; CUX1; SRCAP; SPEN; ZNF589; BCLAF1; SUPT5H; HMGB3; VDR; VEZF1; ZNF226; CREG1; SND1; RNF111; NELFB; TCF4; TRIM27; NR2F1; RB1; PIR; ZBTB20; RBBP7; NFIB; ZFPM2; ZFX; PBX1; CREB3L2; HHEX; TTF1; ZBTB38; POLR3C; PDLIM1; LMCD1; CTCF; ID1; ZSCAN12; PPRC1; HCFC2; MED6; RNF138; ZNF160; TRIP4; TCF12; GTF2A2; AATF; EHF; RUVBL2; EN1; HEY1; RBBP5; ARL2BP; BLZF1; TMF1; ZBED1; DR1; FOXJ3; ZNF667; FLNA; ZNF274; FEZF2; ZNF195; ZMIZ1; ZNF432; RREB1; SOX17; SP100; MBD2; ZNF124; MED4; ZNF544; YAP1; ZEB2; PBRM1; ERG; SMARCB1; CNOT6; ZNF593; KAT2B; ZKSCAN1; BMI1; ZNF551; TRPS1; UBE2L3; SMARCD3; ZNF22; RYBP; ZNF623; ZNF721; TRIM22; SMARCA5; C1QBP; MED14; MAF; FOXN3; SP140L; ZNF264; ZNF24; INSM1; CTR9; TDRD3; ACTL6A; NRIP1; SMAD4; ZBED2; DACH1; DNAJC2; URI1; NFE2; MYBL1; CCNH; CENPF; PPARG; TEAD4; EPAS1; PSMC3IP; HOXA10; NFATC3; MEF2C; ZNF611; TFAP2C; TCF7L2; ZBTB11; PEX2; DEK; ZNF345; ELK3; TLE4; WT1; TOX; HOXB2; TBPL1; LIN28A; ID3; HMGA2; PHIP; EDF1; BNC2; NANOG; SUPT3H; TOB1; SERTAD2; TCF21; SAP18; XBP1; BASP1; ARID4B; RLF; STAT6; RAN; RAD21; CRK; TGFB1; TRIM29; HIC2; ING2; SMARCA1; NRBF2; NR2F2; DNAJC1; ELF5; TSC22D2; YWHAB; GATA6; HSBP1; KDM5D