Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60280	Vorinostat	GSE92742	SKB	Human	24h	10uM	EID0339

Response Information :

Types	Number	Response transcription factors
Up-regulation	119	GATA2; NEDD8; STAT3; COPS5; RCOR1; HMG20B; HABP4; HDAC1; ECD; HLTF; ENO1; TLE1; TBP; NFIL3; SETD3; MTF2; CHD7; ZBTB11; URI1; CTR9; CRY1; WWC1; RNF10; EZH2; HDAC3; IKBKAP; RUVBL1; GTF2A2; ZFHX4; NRBF2; PURA; DRAP1; SIX1; ELK1; PRKDC; TSC22D4; SNIP1; DR1; MLLT10; HSF2; PAWR; TSC22D2; CRK; KMT5A; ING2; TRIM16; RHOA; HDAC2; EDF1; ID2; SOX9; TAF12; NFATC3; POU2F2; RNF141; NCOA4; ZNF165; CCNE1; SERTAD2; DACH1; BHLHE41; SPEN; SMARCA5; TEAD1; ADRB2; CREG1; MITF; MNAT1; SUPT4H1; RUVBL2; CCNC; MLX; RERE; PDLIM1; HEY2; BIRC2; RNF4; RUNX3; MED21; TSG101; TAF10; MED1; E2F5; TOB1; RBBP4; SAP30; C1D; IRX5; YWHAB; PRRX1; AFF1; FLNA; HMGN3; ADNP2; ID3; BANP; FOSB; ID1; DNAJC1; TWIST1; TCEB2; TBL1XR1; SAP18; NFE2; ELF3; HOXC6; FOXC1; MSX1; ZNF331; NKX3-1; STAT1; ATF3; PBX3; MNDA; HOXC10; ZIC1; TOX; ZBTB18; ZNF586
Down-regulation	163	HMGB1; ARL2BP; ZNF124; SP3; ATF5; TGFB1I1; NR1H2; RBM39; ZFP36L1; FOXE1; BNC1; KLF7; ZFPM2; AR; SCAND1; FOSL1; DNMT1; BNC2; ZHX2; NHLH1; TCF25; PRDM2; TXNIP; TGIF2; MEIS2; NEUROD6; RRN3; RBFOX2; BARX1; CERS4; HSF1; HMGB2; ZNF688; WIZ; CEBPD; ZNF219; HIPK2; GMNN; CD3D; KLF10; CTCF; KLF13; LHX2; TFAP2C; ZNF264; PKNOX2; ZNF444; SP140L; MAML1; SALL2; STAT6; ZNF74; TFAP2A; CNOT6; IRX4; NKX3-2; ESR1; HOXD11; IFI16; ZNF345; IRF6; MYBL2; MAFB; ZNF770; SMARCB1; TP53; ATN1; CTBP2; SOX13; TAF5L; ZNF771; AEBP1; MED16; CHD9; PGR; AIP; TCF7L2; ELF4; POLR3C; HOXB2; CHD3; CDX1; PBXIP1; ZNF267; PMF1; HOXA11; ZMIZ1; MEF2A; EGR3; JUN; BACH2; NFATC4; RAD21; CARM1; WWTR1; ZNF423; SUPT3H; MEF2C; ARID5B; FOXM1; PSIP1; CNOT3; EHF; CTBP1; ZBTB16; ZNF12; CNOT2; NFAT5; FOXO1; AES; AGO2; ZFP36L2; CCNT1; PRMT2; NFKB1; CBX5; INSR; ZNF85; ST18; TCF3; ZBED1; RNF138; RBL2; SP100; RORA; HOXB13; WT1; HIRA; DMTF1; BTG1; RREB1; HMGB3; NKX2-1; NFIC; FOXA2; TULP3; STAT4; CTNNB1; ZNF83; SPDEF; KLF2; PAX5; KAT6B; NFE2L1; ZEB1; SLC2A4RG; CUX2; BCL11A; JUP; IRF9; GATA6; MYB; RBPMS; ZNF589; FOXF1; TRIM22; SOX17; ERBB4; HOXA5; CREB3L2; KDM5D; EGR2; E2F2