Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60183	Celastrol	GSE92742	SKB	Human	24h	10uM	EID0339

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	FOSL1; CXXC1; ZNF165; ELK1; RNF141; MYC; TBX2; MED1; ATF5; BHLHE40; ECD; TBP; ETV4; KLF4; EPAS1; NEDD8; FOXO3; TAF1D; MTF1; PRRX2; SMAD3; EDF1; TAF12; TSC22D2; TFE3; HDAC1; HMGA2; ZNF226; DRAP1; ZSCAN31; TCERG1; RBM39; CBX6; ATF4; PDLIM1; KDM2A; ELF1; MAF; SMARCA5; NRBF2; ENO1; PTRF; TCF4; SSRP1; SPEN; SCAND1; SOX9; NFATC3; RBBP7; MAFG; RB1; BRD8; SREBF2; HOXC6; POU5F1B; FLNA; TRIM16; TRAK1; MYCBP; RERE; BASP1; INSR; PURA; ING2; YBX1; MSX1; RBPJ; PBX3; KLF6; MEIS1; RBBP4; TOB1; RXRA; TCF20; TAF10; TCEB2; SAP30; MAFB; TBL1XR1; FHL2; CITED2; NFE2; ZNF589; TWIST1; CALR; CREG1; YWHAB; ERBB2; PIR; RUNX3; ZFP36L1; MYRF; ABL1; ZBTB18; MECOM; FOXD1; KLF5; HOXB6
Down-regulation	145	HMG20B; USP22; GMNN; CITED1; ZNF415; ID4; WWC1; TCEA1; HOXD1; ZNF254; ZNF394; ZSCAN16; CREBL2; ZSCAN9; NR3C2; ZNF85; NRIP1; TAF5L; GTF2F1; ZNF43; ZNF136; HEY1; TDRD3; MECP2; CD3D; ZNF264; HLF; MEIS2; TERF1; ZNF14; ITGB3BP; SSX1; ZNF124; REPIN1; ZNF345; CDK2; TAF4; THAP10; ZNF623; RSF1; HDAC9; ZNF354A; ZNF444; HIRA; TFAP2A; NEUROD1; TFAP2C; ZNF180; ZFPM2; AES; MYT1L; IRF2; ZNF44; ATF2; TRPS1; NCOA1; ZNF551; TLE2; BRD4; FOXA1; CBFA2T2; TRIM24; ZNF304; ERBB4; IL16; TOX; PFDN5; CNOT3; E2F8; LITAF; HOXD3; MZF1; ZNF134; LEF1; JUNB; MKL2; ZNF350; SMAD7; INSM1; MYBL2; MED21; SALL2; RAD21; TDP2; TCF7; SPIB; TCF21; MDM2; RBBP8; NR4A1; ZNF331; ZNF606; ZNF419; ZNF586; NFIB; ZNF587; PNRC1; SATB2; NKX2-1; RBL2; SOX13; BPTF; ASCL1; HOXB13; MAML1; HMBOX1; HOXA10; JUND; CERS6; E2F5; STAT1; SALL1; ST18; GATA6; STAT4; POU4F1; RNF138; ESR1; KLF9; SMARCA1; IRF4; SSBP2; ZNF544; ZIC1; ZSCAN18; JUN; TOX3; FOXG1; ATF3; DMTF1; CREB3L2; ZHX2; BBX; ZNF93; TGFB1; KLF2; CREB1; JUP; POU2AF1; MYBL1; WT1; NR2F1; IRF9; EYA2; E2F2