Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60182	Withaferin-a	GSE92742	SKB	Human	24h	10uM	EID0339

Response Information :

Types	Number	Response transcription factors
Up-regulation	135	EGR1; SATB1; GATA2; FOXF2; NR4A2; ATF3; CIR1; RELB; EZH2; DDIT3; VDR; CHAF1B; HOXD1; SNAI1; TAF12; TRIM29; ETV4; E2F1; HIC2; DLX2; BARX1; HMGB1; E4F1; SUMO1; CDK2; BATF3; MTF2; AIP; PRRX2; TCF7L2; PDLIM1; LEF1; NR4A1; HSF4; NKX3-2; MED17; PCGF3; MEIS2; PFDN5; MAFF; HOXC5; VPS72; JUNB; DLX5; ZNF331; ZNF273; PIAS1; FOS; ST18; FOSL2; TWIST1; SALL2; MXI1; SERTAD2; CCDC59; EN1; BATF; CITED2; PRDM1; SOX13; CCNH; FOXO4; VGLL1; RARG; TFAP2C; NKRF; HMGN3; MED15; CREM; MED21; CHD1; ID2; RFXANK; POLR3C; REL; SHOX2; HOXA1; MYBL2; ETV6; ERG; TEAD3; CBX6; TBX21; IRF1; SSBP2; ARNTL2; HHEX; SUPT3H; UBE2B; TCF20; SPDEF; RBBP8; TGFB1; HOXA11; SPEN; ZBED1; ELF4; KLF11; HDAC5; SUZ12; FOSB; ZBED2; IRF4; JUP; HOXC10; ZNF32; TCF3; BRD7; RORA; NCOA2; BCL3; SOX9; MYRF; ZNF430; ID3; HOXA7; CREB3L2; HOXB2; NFE2; TLE4; ZNF589; EYA2; HOXA5; TBPL1; MYB; HES1; RBPMS; PBX3; HIRA; MYBL1; IRF9; ZNF91; WT1; FOXD1; HOXB7
Down-regulation	123	TSC22D3; PUF60; USP22; CRK; FOXO3; CBFB; WWTR1; TADA3; TXNIP; CDYL; NCOR2; BAZ1B; NFKBIA; MAGED1; ZMYND8; ZBTB38; TCERG1; SREBF1; GTF2I; CNOT1; ZEB2; MAF; SNAI2; HDAC6; HNRNPD; ZNF587; CREB5; SP110; REPIN1; NR1D2; HIPK3; ZNF148; SMARCE1; ZNF264; ASCL1; ASH2L; HSBP1; ZNF189; FOXA1; SOX11; CREBL2; ZNF468; NR2F2; TSC22D1; NELFB; ZMYM2; MEOX2; MITF; ZNF160; RNF4; SMARCA5; ZNF721; TCF12; PTTG1; ZNF302; HOXA10; ZNF512B; ZNF419; PRKDC; HEY1; TAF9; DNMT3B; KLF2; PLAGL1; AHR; UBP1; SMARCA1; NCOA4; TAF10; LHX6; TP53; MTDH; AFF1; ERBB2; MYCBP; BCLAF1; MAML1; MTA1; CERS6; SMARCA4; BMI1; TBL1XR1; BIRC2; TOX3; CTNNB1; SIX1; PBRM1; ELK3; MEF2C; TLE2; STAT1; ZNF623; RBBP4; ZBTB20; ZNF134; TRIM22; RB1; TRIM28; BASP1; SMAD2; RBPJ; ADNP; HMGB3; SMAD4; ZNF536; YWHAB; ZBTB16; KLF6; NFE2L1; ZNF551; YEATS2; PEG3; YBX1; ACTL6A; LMCD1; NR2F1; MBD2; FOXJ3; FOXG1; ZNF586; DACH1; KDM5D; NR3C1