Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60143	Motesanib	GSE92742	SKB	Human	24h	10uM	EID0339

Response Information :

Types	Number	Response transcription factors
Up-regulation	156	SMAD3; SMAD5; GLI3; GTF2I; SOX4; NEDD8; PPARGC1A; TSC22D3; ELK1; FLNA; BRD8; EPAS1; FOXO4; HDAC4; ZEB2; NUP62; RNF141; TCF15; PHF20; CASZ1; EGR1; NFKBIA; ASXL1; HIPK3; RBBP4; HDAC1; USF2; VGLL4; CHD7; ATF1; ELF1; MLLT10; SPEN; MYOD1; MEF2C; ZFP64; KDM2A; TADA3; PSPC1; FOXO3; GTF2A1; DRAP1; HMG20B; ZNF226; PUF60; HIVEP2; NR1D2; ZNF143; HLTF; ARID4A; BAZ1A; KAT5; SREBF1; TRIM16; TBP; BRPF1; ATF7IP; BRD3; PITX1; MAX; ZBTB18; PDLIM1; TBL1X; ZBTB40; CRK; SMARCE1; RNF10; ZNF146; MAF; ZBTB1; PTTG1; SAP18; RCOR1; RFX5; CITED2; RERE; RB1; NCOA2; ZMIZ2; SETD2; CIC; TRAK1; KLF6; LPIN2; SAP30; ZMYM2; FOSL2; KDM5B; ARNTL; MED6; SOX9; MITF; ING2; IKBKAP; ZNF84; TLE4; TRIP6; TAF10; ZNF302; NONO; ATF4; BCOR; MYCBP; ZBTB38; BCLAF1; TEAD1; RLF; GTF2IRD1; MNT; PRPF6; EDF1; NCOA4; CRY1; VEZF1; UBE2B; HTATIP2; HOXA10; BCL3; SNW1; SAFB2; HBP1; HOXC6; CBX3; NFATC3; NKX3-1; MAML1; KAT8; MAFB; RHOA; TRIM28; BAZ2B; DNAJC1; CTNNB1; NR2F2; GTF3A; PAX6; KLF9; ADNP; IRX5; KLF5; UBE2I; SCAND1; TCF4; FOXC1; FHL2; SIX2; PCGF2; ERBB2; FOXD1; DACH1; YBX1; BASP1; FOXG1; NR2F1; MEIS1; KDM5D
Down-regulation	127	CD3D; ZNF415; GMNN; NR2F6; FOXE1; THAP11; NANOG; BNC1; COPS2; DNMT1; SALL2; OLIG2; ZBTB44; BRIP1; MYBL2; TFDP2; ID4; NCOA3; ATN1; ZFP69B; ZFPM2; ZNF345; PGR; RBBP8; ATF3; CDK2; PHIP; MEIS2; LOXL2; KLF10; TAF11; SNAI2; SOX13; TCF21; ASCL1; ZNF268; SUPT7L; BARX1; SUPT3H; TCF7L2; HOXA1; TDP2; POLR3C; SPIB; ZFHX3; BNC2; RING1; TFAP2A; ZNF331; RFXANK; CCNT1; SKIL; TBX1; ZNF12; TCF7; KLF13; TGFB1I1; GRHL2; ZNF124; IFI16; IRF6; CREB3; IRF9; ZNF85; PSMC3; FOXM1; ETV5; ZSCAN18; ELF4; PBX1; EHF; SMAD7; PEG3; AR; ZNF136; NR1H2; ZNF91; TULP3; ZNF512B; NR4A2; ZNF232; ZNF43; CNOT2; ZNF264; ESR1; ELF5; HOXD1; CHD9; CALR; JUN; HOXB13; TFAP2C; CUX2; LITAF; CBFA2T3; NFATC4; INSR; GLI2; GATA6; NR5A2; SSBP2; HDAC9; SOX17; HOXB2; ZMIZ1; CERS6; INSM1; RUNX1; ZNF93; ZNF551; DLX2; ZEB1; ID3; YEATS2; WT1; TP63; MECOM; EYA2; ZNF589; EGR2; AEBP1; POU2AF1; ZIC1; ZNF586; ERBB4; EMX2; E2F2