Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60121	Safinamide	GSE92742	PHH	Human	24h	10uM	EID0338

Response Information :

Types	Number	Response transcription factors
Up-regulation	47	ATF3; NR4A3; ZNF331; NCOA2; PAWR; SOHLH2; NR2E1; KLF11; MAFG; MLXIP; NR1H2; CREG1; ZMYND8; TAL1; GATA1; NR5A2; ZNF611; STAT1; CDK2; HIPK1; LEF1; TCFL5; KLF1; PHF20; PAX6; PGR; DNMT1; STAT4; IRF4; PBX3; MXI1; HMGB2; TCF7; NR4A2; IRF6; DACH1; DLX2; ZSCAN18; CD3D; ZFP36L1; OSR2; GATA2; HIRA; MYBL1; WT1; NCOA3; AEBP1
Down-regulation	64	TCEA2; TWIST1; HDAC2; ZNF468; IRF2; MLX; BMI1; LZTS1; HSF2; MED23; ETV5; BAZ1B; BCL6; IKBKAP; CBFB; RBM14; NFE2L1; ATF1; MAFB; ERG; PIR; GABPB1; SMAD1; SMAD3; SIX1; NPAS2; ING1; NCOR2; MAGED1; ETS2; POU4F1; MSX1; APEX1; CITED2; FOSL2; SMARCA4; FOXO1; DNAJC1; ELK3; IFI16; HOXB6; HMGN3; CREB5; ZNF512B; ERBB2; SMAD6; MECOM; AHR; HLF; ID1; SPEN; HOXA5; BAZ1A; ARID4B; TP53; HEY1; WWTR1; FOXC1; EDF1; NR2F2; KLF4; NKX3-1; TXNIP; CEBPD