Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60106	Canertinib	GSE92742	PHH	Human	24h	10uM	EID0338

Response Information :

Types	Number	Response transcription factors
Up-regulation	109	NCOA2; PLAG1; HOXA11; BACH1; TEAD4; SHOX2; TFCP2L1; MECOM; RBM39; CIR1; TULP4; CDIP1; KAT2B; KLF3; E4F1; HOXC10; GATA3; FOXE1; SP100; TRPS1; MED13; RREB1; IRF9; TOB1; PAWR; NCOA6; SMAD2; EZH1; BACH2; TAF5; MKL2; ZNF43; NFYC; CDK9; NCOA1; NFE2L1; BARX1; MED20; SP140L; KLF13; AFF1; ZBTB16; TAL1; ZNF217; STAT1; HOXA10; TCF7L1; HMGB2; LHX6; DLX2; ZEB1; MED17; ZNF331; IRF7; IRF6; CTR9; ZFP36L2; FOXL2; CBX4; RARA; ESR1; LEF1; DNAJC2; NR1H2; MXI1; PBX3; ZMIZ1; TFAP2C; SSBP2; LIN28A; TULP3; CDK2; THRA; FOXM1; MYB; OSR2; FOXA1; FOXN3; DAXX; RBBP8; EN1; ZNF394; CREB3L2; KLF9; TP63; AEBP1; CALR; KLF1; POU4F1; OLIG2; ZNF91; PSMC3; CBFA2T3; ZNF12; ZIC1; LITAF; HES1; BTG1; NR4A2; ELF4; NFATC1; HMGB3; ZKSCAN1; PBX1; EYA2; ERBB4; MYBL1; POU2AF1; FOXD1
Down-regulation	126	EZH2; CBFB; RBBP4; RFX5; NFIB; RUVBL2; ZNF468; RBBP7; WWC1; PTTG1; ZBTB38; KMT2B; CIC; ASXL1; CCNA2; ZNF226; TSC22D2; SREBF2; HMBOX1; POLR2A; CARHSP1; TOX4; FOXN2; EGR3; MYCN; NAB1; ZNF672; ZNF302; ING2; TRIP6; ZEB2; MKL1; MYCBP; DRAP1; ZNF329; BCL3; STAT5A; ZNF165; CBX3; BAZ1A; C1QBP; HMGB1; ZNF432; TFEC; DR1; SOX11; CITED2; NPM1; RBPMS; BCL6; HAND1; MSX1; BRPF1; ZNF22; NR0B1; HCFC2; TRIM28; MAF; FOSB; TRIM16; URI1; ZNF783; IRF8; GABPB1; PIAS2; ZNF146; MITF; INSM1; APEX1; BATF3; NFAT5; ZMYM2; ZNF410; NEDD8; SMAD3; BATF; AHR; ING1; HLTF; NCOA4; BBX; ENY2; SPEN; EED; PLAGL1; RORA; CREB5; EYA1; BASP1; ELF1; PEG3; ID2; ZBTB1; ZBED2; GTF2A2; GTF2IRD1; MNT; SIX1; ZNF721; NRBF2; RCOR1; FOSL2; NKX2-2; HMGN3; MEIS2; ZNF160; FLNA; TCERG1; FOS; HOXA5; TBX2; RUNX3; ERBB2; ISL1; MEF2C; YBX1; EDF1; HOXB7; CHD7; HEY1; ELK3; DACH1; TSC22D1; EGR2; KLF10; TXNIP