Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID60038	Withaferin-a	GSE92742	PHH	Human	24h	10uM	EID0338

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	HOXA10; FHL2; PSMD9; FOSL1; HOXA11; DRAP1; DDIT3; MAFF; ZNF143; SIRT7; ATF3; EGR1; BHLHE40; VGLL4; MSX1; SMAD5; TRIP6; DBP; TWIST1; YWHAB; JUND; NUP62; ZNF669; ZIC1; ZNF473; TBP; FOXD1; SSBP2; WHSC1; MED6; HDAC9; PTRF; SP110; MXI1; BRIP1; BRF2; SIRT2; BATF3; SP2; KLF12; IRF7; GABPB1; KLF6; MXD1; SIX2; SAP18; TLE1; RELB; SMAD7; ZBTB43; RBBP5; TEAD1; SERTAD2; ZNF91; PPP1R13L; BRPF1; ZNF586; HOXC10; SETD3; BASP1; KAT2B; ZNF175; SNAI1; NFE2L1; BCL10; RYBP; CEBPG; ZNF394; NR1D2; CD3D; RHOA; ATF4; JUP; TRRAP; FOXC1; ZFP36L2; CCNT1; MED27; TBPL1; MECOM; KLF7; FOXO3; PSPC1; PITX2; BAZ1B; MED16; TRIP4; NFIC; FOSL2; ELK3; IRF1; RUNX3; PBX3; ENO1; GTF3A; SATB1; AFF1; MDM2; MNDA; MYB; NCOA1; STAT1; IRF9; FOSB; VPS72; ZKSCAN1; KLF4; FOS; MAGED1; LITAF; TXNIP; EDF1; SCAND1; KDM5D
Down-regulation	115	THAP11; PDLIM1; NRIP1; NFKBIA; STAT5B; IKBKAP; CCNA2; SNAI2; CBX5; EZH2; NPAS2; FOXO1; ZBTB14; GATA3; NFIL3; SFPQ; WNT4; NR1H4; FOXO4; RREB1; COPS2; PBX1; SOX3; NANOG; HIC2; ZNF226; NFIB; SOX11; ZBTB3; NR0B1; MAF; BCL11B; LIN28A; FOXM1; ALX1; NCOR2; CNOT1; CENPF; HES1; BRD7; KMT2A; FOXA2; PRRX1; STAT5A; BNC2; E2F3; HMG20B; E2F8; ZBTB20; HLF; SMARCE1; URI1; POU4F1; MEIS2; FOXG1; ZBED1; PRKDC; ZIC3; HEY1; HHEX; SMARCA5; ZFPM2; RNF111; TCF7L2; HOXC4; TCF12; BCL6; ZSCAN16; MKL2; SSX1; GRHL2; TGIF1; DMTF1; ZBTB16; FOXA1; ITGB3BP; DNMT3B; PEG3; AEBP1; ZNF232; CEBPZ; ENY2; SIAH2; INSM1; HTATIP2; SMARCA1; CREBL2; ZNF131; TFEC; VDR; ZNF467; HLTF; PGR; MYCBP; SMAD3; NR1H3; SALL2; NFE2L3; ATF1; PURA; BHLHE41; HOXA5; DAXX; HIRA; IL16; SPEN; ASCL1; NR2F1; SMARCC1; LOXL2; MEF2C; NKX2-1; ID1; ERBB2; ID4