Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59978	Safinamide	GSE92742	PHH	Human	24h	10uM	EID0337

Response Information :

Types	Number	Response transcription factors
Up-regulation	60	MITF; TSC22D1; MYC; CEBPA; HLF; NEDD8; BBX; TXNIP; MYCBP; HSBP1; SSBP2; NR3C2; MTDH; CRK; PFDN5; ETV5; KAT6A; RCOR1; PTTG1; HDAC4; BCL11B; FLNA; USF2; BAZ1A; ZNF226; CTNNB1; DNAJC1; PEX2; ZNF410; MXD4; CREBZF; SCAND1; SP110; FOXO4; MAZ; SP3; BATF; EMX2; FOXO3; RUVBL2; TOX; LITAF; UBP1; BHLHE41; BMI1; CD3D; BRD4; DRAP1; TAF10; FOXD1; SIAH2; ZBTB18; ELK3; TOB1; HMGA1; MAF; MAFB; TOX3; NR2F2; BASP1
Down-regulation	58	CHD7; EN1; URI1; ERBB4; TCEA2; CCNE1; ZNF587; ZNF232; SIX1; PRKDC; TCF7L1; NFE2L3; MEOX2; MYCL; ID4; CEBPD; BRD3; INSR; NR2F6; HOXA1; HOXB2; ZNF195; LIN28A; E2F8; AEBP1; HMG20A; NFATC3; FOXO1; LMCD1; BACH2; RBBP8; TAL1; FLI1; PBX3; ZNF589; CREB1; BLM; SOX17; PEG3; EGR2; DACH1; CITED2; ZNF131; INSM1; NR4A2; ZFPM2; ZIC1; PSIP1; GATA6; NR1H2; FOXC1; MEF2C; TRIM22; ZNF160; DLX2; IRF4; ID1; ZEB1