Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59954	Lopinavir	GSE92742	PHH	Human	24h	10uM	EID0337

Response Information :

Types	Number	Response transcription factors
Up-regulation	139	CREG1; HMGB2; PIR; NKX3-2; SSBP3; MXI1; HIVEP3; MYCL; ZNF552; SALL1; MECOM; AIP; SP2; BAZ1A; SFMBT1; EYA2; ZNF580; MDM4; TBX2; HOXA11; INSR; ZNF274; GLI3; WDR77; NFKBIB; TRIP4; FOXJ1; FOXL2; KAT2B; RELA; GTF2F1; ZBTB48; PRDM10; CREB3L1; HMGB1; EP400; KLF12; CTNNB1; ZBTB39; HNRNPD; CCDC59; CBFB; RORA; AATF; CTBP1; LEF1; BRD2; SIM2; RING1; SOX10; CRYM; TCEB2; TFCP2L1; TCF25; SREBF2; HOXC4; CREM; MYBL1; PITX1; CCNT1; TAF5; PBX2; SSBP2; ZNF516; NFX1; ZNF239; NFE2L2; EMX2; SUB1; HDGF; PHF1; ZNF107; PLAG1; ZMIZ2; ZFHX3; WT1; PTTG1; DDX17; LHX2; XRCC6; ESR1; SIX2; KAT5; JAK2; BAZ2B; STAT4; GCFC2; SATB2; KLF2; TXNIP; TSC22D2; KDM2A; ADNP2; CD3D; BCL11B; SOX13; NFIC; ZFP36L1; SMARCC1; LITAF; ZNF410; POU2AF1; ZNF83; ERBB2; BATF3; GRHL2; NR2E1; PBXIP1; MBD2; MSX1; FOSL1; ELF1; FOXD1; TGFB1I1; TFEB; TCF7; SOX17; HMG20B; YWHAB; GATA6; TAF10; IRF2; ARID4B; CDK2; ZNF91; GATA3; FOXC1; KLF10; RFX5; NFATC1; BASP1; MEIS1; PBX3; PSIP1; NKX3-1; MYB; LMCD1; SMAD7; CITED1
Down-regulation	164	TRIB3; MTF2; CCNA2; NRIP1; EZH2; ING2; KAT6B; HIF1A; NFE2L1; POU5F1B; IKBKAP; HBP1; ZZZ3; ERG; UTF1; CREBL2; DR1; HHEX; ZNF146; TLE4; BCL6; ENY2; SREBF1; KMT2B; PEG3; ST18; TULP3; TERF1; URI1; VEZF1; ZNF768; WWC1; TCF4; HEY1; NEDD8; TBL1XR1; MYCBP; ZNF248; HLTF; TRIM28; WIZ; NANOG; DNMT3B; CREB1; USP22; IL16; TCEA1; ID2; BRD7; RYBP; DDIT3; TGFB1; AHR; TEAD4; RNF14; CCNE1; NFATC3; TERF2; SMARCA5; INSM1; NR2F6; NR1H4; RBPMS; MAML1; ZNF302; BNC1; CRK; E2F3; PURA; EN2; ADNP; ZBED2; JUNB; RAD21; MED4; CEBPD; ARNTL2; NEUROD1; FOXF2; SIX1; STAT3; ZKSCAN1; TSC22D1; ZBED1; ZNF665; ZMYND11; MNT; ZBTB38; HDAC9; LIN28A; TRIM16; E2F8; PITX2; BANP; DACH1; ID3; RERE; CTBP2; REPIN1; ZNF7; ZNF329; ZNF432; CDYL; NFE2; KLF5; BIRC2; EHMT2; SFPQ; IRF8; E2F6; NFAT5; FUBP1; PRRX1; ZNF467; BCL3; ID1; EPAS1; ZFP64; ZNF148; GLI2; ZNF423; WWTR1; CLOCK; ZIC1; NRBF2; CBX6; ZNF22; MAF; NR1D2; E2F5; SMARCE1; ZHX2; ETS2; ZNF12; TBX3; FOXE1; MEF2C; IRX4; MED13; ZNF532; DMTF1; TFAM; ZNF165; EGR3; ATF1; TSG101; ZFPM2; KLF4; NR0B1; CITED2; CARHSP1; PRRX2; BRD4; PAX6; VPS72; BHLHE41; SOX9; TFAP2C; SIAH2; HES1; ZNF217; SMARCA1; ASCL1; ZMIZ1