Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59946	Hydroxycholesterol	GSE92742	PHH	Human	24h	10uM	EID0337

Response Information :

Types	Number	Response transcription factors
Up-regulation	87	ECD; ID2; HIVEP2; AATF; HLTF; PIAS2; RBBP7; EZH2; BBX; NUP62; SNW1; MED6; SUV39H1; HNRNPD; ING2; CEBPA; TSC22D1; NRIP1; HLF; BRD2; ZEB2; HSBP1; MTF2; NCOA4; HOXA10; FOXO4; EMX2; PURA; BTAF1; HSF2; BAZ1A; ITGB3BP; SMARCA4; DNMT3B; SOX10; MITF; FLNA; USF2; ELF1; YBX1; TSC22D2; DNAJC1; DDX17; PTTG1; DRAP1; UBE2B; CCNA2; RBBP4; CTNNB1; CENPB; ING3; NKX2-2; MLX; XBP1; NFKBIA; SATB2; KLF4; RFX5; NR0B1; CBFB; MED1; JARID2; EGR3; CITED2; DMTF1; TGIF1; HMGB1; BIRC2; PITX1; POU4F1; TBL1XR1; ATF3; TOB1; YWHAB; BHLHE41; ZNF721; MSX1; SAP30; TOX; SCAND1; ATF1; SMAD3; CARHSP1; KLF10; FOSB; BTG1; KDM5D
Down-regulation	84	ATF5; IRF9; ZNF211; ZNF606; CREB1; HOXA5; WWTR1; ZFPM2; ZSCAN31; TRPS1; KLF7; NPAT; HMGB2; EZH1; RBL2; PLAG1; TULP3; ZKSCAN5; HOXB2; ZNF117; ZNF217; MEIS2; BAZ2A; SOX2; PAWR; HMGB3; HLX; BNC2; ZNF195; ID4; ZNF232; SKI; NFE2L3; ERG; SMARCA1; TAL1; TCF7L1; ISL1; DLX2; KLF13; CUX2; IRF6; CTBP2; HOXB5; HOXB6; CHD7; CBFA2T3; GATA6; YEATS4; TGFB1I1; MYCL; PBX3; MDM2; ZNF43; BACH2; HMGA1; ARID4B; ID3; ZSCAN18; SOX17; IRF1; ZEB1; PBX1; ZNF532; SMAD1; RAD21; ZNF512B; SOX11; ZBED2; HIVEP1; ELK3; MYBL1; IRF4; PSMC3; ZNF589; CREB3L2; INSM1; LEF1; NR2F1; MKL2; WT1; ASCL1; NKX2-1; ZBTB18