Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59914	Lithocholic-acid	GSE92742	PHH	Human	24h	10uM	EID0337

Response Information :

Types	Number	Response transcription factors
Up-regulation	117	TBX2; MXI1; TWIST1; ZNF274; FOXL2; BRD2; IKZF1; ZNF580; RARA; TCEB2; BTF3; ZNF239; GLI3; TFDP1; SHOX2; NFKBIB; DNMT1; ZNF211; HOXC4; TAF5; ESR1; HDAC4; KAT2B; TXNIP; ZFP36L2; ZNF586; SSBP3; PBX2; ESRRG; NFE2; ZNF500; WT1; BATF3; PHF1; ZNF91; TCF25; NAB2; SOX12; E4F1; LITAF; HMGB2; NR0B2; BAZ2B; NFE2L2; KLF1; HOXB2; IRX5; ZNF281; EP300; RUNX3; ZNF184; SALL1; SIX2; AFF1; PCGF2; CEBPD; HOXD3; CD3D; ZNF331; TFDP2; STAT4; TAL1; ARID5B; SERTAD2; CDK2; ZNF410; SREBF2; SSBP2; ETV5; MSX1; MYBL1; RXRA; RFX5; ALX1; MEIS1; DDX17; ZNF93; FHL2; CRY1; NR5A2; ZNF516; NKX2-2; FOXD1; TGFB1I1; ARID4B; LHX3; HOXA11; DLX2; TGIF2; SOX17; ERBB2; PIR; EYA2; DRAP1; TCF7L1; BAZ1A; JUP; BLM; ZNF131; HOXB5; HOXB6; ZNF83; EMX2; ZNF266; IRF4; HOXB7; LMCD1; NR4A3; NFIC; YWHAB; GATA3; AGO2; OSR2; ID4; ZEB1; NFATC1; MAFB
Down-regulation	132	EZH2; CCNA2; TCEA1; HLF; MTF2; TERF1; CRK; DACH1; KAT6B; KLF5; USP22; NRIP1; VEZF1; ARNTL2; ZKSCAN1; ZNF146; ISL1; SREBF1; NFIB; TRIM28; ITGB3BP; BCL6; GABPB1; WWC1; C1QBP; MYCBP; STAT3; NPAS2; MLLT10; NR1D2; REPIN1; TGFB1; PRKDC; RBPMS; HLTF; NUP62; ADNP; ENY2; TRIM29; SOX15; NCOR1; ETS2; RBBP8; RNF14; WWTR1; NR1H4; NR2C1; EHF; TLE4; ZBTB20; ZMYND11; CHD7; NANOG; TCF4; ERG; TBL1XR1; NR2F6; EGR3; ZNF248; SFPQ; MYT1L; TRRAP; NFIL3; FOSL2; CBX3; CBFA2T2; TLE1; NKX3-1; TRIM22; TCF20; AHR; NEUROD1; IKBKAP; DR1; TP63; INSM1; SMARCA5; ELF3; PEX2; PLAGL1; JUNB; SOX9; ST18; MDM2; DMTF1; CCNC; ELK3; GTF2I; ZNF12; HHEX; SMARCE1; BHLHE41; ASCL1; TFAM; NFE2L3; RNF111; SSX1; E2F5; IRF8; HMGA1; PPARGC1A; FOXA1; UBP1; NRBF2; ATF1; NR0B1; GRHL2; SMAD4; ZNF22; EYA1; POU4F1; SMARCD3; ELF5; MEF2C; PAX6; RNF138; MYBL2; NFAT5; IFI16; RUNX1; HIPK3; TRIP6; KDM5D; NR1H2; FOXF1; MYB; SMAD7; SAP30; VPS72; FOXG1; ZEB2; PSIP1