Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59906	Apha-compound-8	GSE92742	PHH	Human	24h	10uM	EID0337

Response Information :

Types	Number	Response transcription factors
Up-regulation	179	NFKBIB; TWIST1; HR; MTA1; HOXC6; TSC22D3; POU2F1; AIP; ID2; RHOA; LZTR1; TXNIP; PPARD; SP2; MYCN; ZBTB17; LEF1; SATB1; TCEB2; SMARCA4; MXD3; NONO; BHLHE40; ATF6; CENPB; SREBF1; IKZF1; ZFHX4; SHOX2; NHLH2; ZNF492; PAX9; PPP1R13L; TRIM25; HMG20B; IRX5; SSBP2; IRF3; PCGF3; BAZ1A; ZNF286A; HIVEP2; CXXC1; TRIM29; YBX2; ZNF580; RBL2; PAXBP1; ITGB3BP; ETV5; MAGED1; ZNF473; RBPMS; BBX; CBX8; FOXD1; SETD2; TEAD1; ERCC3; MEF2A; ZBTB39; EZH2; ZIC3; SMARCD1; SMARCB1; TBX19; ESRRG; HLTF; RUVBL2; MXD4; CREB3L1; ST18; ZNF226; RB1; WHSC1; MEN1; SOX11; SALL1; ZKSCAN7; PCGF2; APEX1; VEZF1; PAX5; TOX3; USP21; SPDEF; ZNF587; PIAS2; DRAP1; SPEN; BCL6; CREG1; HOXC4; RBBP7; KLF2; PTTG1; GTF3A; TCF7L1; ELK3; MED14; BLZF1; HLX; SREBF2; DBP; SOX13; ZNF536; ZNF444; MAFB; STAT4; BLM; CARM1; PITX1; BCL11B; SOX10; PKNOX1; BRCA2; PCBD1; TRRAP; RNF4; TGFB1; LZTS1; SMARCA1; LITAF; SOX9; HMGB3; BACH1; NFKB2; EBF2; PHF1; RUNX3; ZMYM2; BRIP1; KDM5D; GTF2I; KAT5; PLAGL1; PIAS3; MEF2C; NR1D2; RNF141; TCF12; GLI2; ZNF219; HEY1; AHR; FOXO3; HOXA10; DAXX; CALR; MSX1; TLE4; TCF7; PITX2; SIRT7; MNDA; TGFB1I1; TCF4; HIVEP1; TRIM22; HES1; TAF10; PSPC1; FOXG1; MKL2; TFAP2C; CARHSP1; BHLHE41; IRF2; PRRX1; IRF8; BACH2; ZNF721; ESR1; NFATC1; DLX2; ZMIZ1; ZBTB18; NKX3-1; CITED1
Down-regulation	167	CRK; THAP11; ZSCAN31; NR2F6; TDP2; ID1; ATF3; ABL1; ZNF84; ZZZ3; PRKDC; SUMO1; MECOM; CREBL2; ARNTL2; ASH2L; EGR2; HIPK1; UBE3A; CSDE1; HNRNPD; CEBPD; GABPB1; BCLAF1; PTRF; ID3; SF1; TGIF1; TAF7; CDK9; TFAP2A; ZNF140; PNRC1; CNBP; ZNF281; RAN; TAL1; MGA; CITED2; C1QBP; TAF11; SP100; PRPF6; JAK2; NR4A1; NFATC4; KLF5; TBX21; ZNF667; CREM; BNC2; GFI1B; COPS5; ZFPM2; COPS2; ING2; USP22; ZNF215; TCEA1; URI1; CHD7; ZNF562; KMT5A; RBM39; KLF1; NFATC3; PAWR; NR4A2; CBX5; ZNF131; TOB1; SMAD6; TFDP1; BRD7; ADNP; FOSB; ZSCAN18; NCOA2; MEIS2; ZNF669; LIN28A; CBFA2T3; ING3; HMGB2; NPAS2; MXI1; NFE2L3; KDM4C; HMGN3; THAP4; SP140L; ZNF177; SFPQ; TAF9; MYB; CERS6; PEG3; ZNF232; CIZ1; RNF6; KLF4; BRD4; PLAGL2; ZNF654; NFE2; TRIM24; CBFB; STAT3; ZNF91; MED17; KLF6; ZMYND8; RLF; ZNF24; FOXO1; AEBP1; LDB1; PEX2; CREB1; HMGA2; CAMTA1; PSIP1; SUZ12; BRD3; SUPT3H; ETS2; GCFC2; TCF21; ZNF217; MYBL2; TP53; ZNF589; ATF4; CHD9; FOXF2; FOSL2; FOS; CNOT2; ZNF189; NFE2L2; WWTR1; TP63; SAP18; TGIF2; PSMC3IP; SMAD3; BMI1; SMAD2; CCNH; HDAC1; ZNF267; PQBP1; RAD21; TFDP2; SMARCA2; ZNF331; GATA6; ZNF512B; NR0B1; NR4A3; HIRA; PBX3; CREB3L2; IRF4; EGR3; NR2F1; HTATIP2