Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59893	Barasertib-hqpa	GSE92742	PHH	Human	24h	10uM	EID0337

Response Information :

Types	Number	Response transcription factors
Up-regulation	107	ATF5; TCEB2; DDIT3; GATA4; MXI1; ZBTB17; SALL1; WDR77; DNMT1; CEBPA; HDAC4; ZFP36L2; BAZ2B; POU2F2; GLI3; MAGED1; HOXA11; FOXL2; MED16; E4F1; MEOX1; SIM1; BRD2; KDM4A; ZNF516; TCF25; HOXC4; PSPC1; GTF3A; ZHX3; ZNF593; RARA; PFDN5; CDK8; MAFG; SREBF2; STAT4; TEAD3; KLF7; ZNF410; NFE2; ZNF263; ZNF711; OSR2; DAXX; ZNF184; ELF1; RORA; ENO1; OVOL1; NCOA1; PSMD9; SIX2; PIR; TXNIP; MYRF; PHF1; MAZ; CD3D; GATA6; ELF4; E2F2; LITAF; ZBTB18; NFATC1; JUN; HDGF; MECOM; TWIST1; RFX5; SSBP2; HOXB6; CCNH; LYL1; SERTAD2; DDX17; ZMYND8; TRIM32; TOB1; DRAP1; IRF6; SAP18; PA2G4; ESR1; DBP; WT1; TGFB1I1; PCGF1; ZNF586; TCF7; HOXB2; RXRA; SIAH2; SCAND1; FOXD1; SMAD3; ATF3; CDK2; EMX2; KLF10; NR2F2; BTG1; MSX1; GATA2; MYBL1; ID4; CITED1
Down-regulation	124	EZH2; CCNA2; THAP11; TERF1; NRIP1; MTF2; SIX1; USP22; CREBL2; ZFP30; NR4A1; HLTF; AHR; EGR2; FOXN3; NR4A2; ZNF146; ERG; PRKDC; SFPQ; BCOR; DEK; TCEA1; INSM1; MTDH; MYCBP; TGFB1; HBP1; NFAT5; CBX5; TFAP2A; REPIN1; ASH2L; NFE2L3; CHD1; ETS2; DNMT3B; ENY2; E2F3; ZNF665; HDAC9; TGS1; ZBTB20; REST; TP63; URI1; PTRF; SOX10; TRIM29; TRIM24; TERF2; ATF7IP; NANOG; CRK; HOXD1; ITGB3BP; ADNP; MYCL; ISL1; ZBTB38; RBM14; CBX3; ING2; RAD21; ZEB2; MLLT10; CHD7; KLF5; GTF2IRD1; NR1D2; BBX; ST18; LEF1; RUNX1; TCF3; XBP1; HEY1; IFI16; DACH1; WWC1; TFAM; BCL10; EBF2; ZNF468; NPAS2; RBBP8; TRIM22; NEUROD1; ZNF302; MDM2; FOXF2; EGR3; NFATC3; SNAI2; SMAD4; ZNF331; FOSB; CERS6; ZNF415; E2F5; BLM; ZBED2; UBP1; BACH2; RBPMS; WWTR1; BMI1; DMTF1; CBFA2T3; ILF2; KDM5D; ZNF532; BIRC2; MEF2C; ZNF131; STAT1; PRRX1; SAP30; ZIC1; PSIP1; EHF; VPS72; HTATIP2; ASCL1