Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59878	Torin-1	GSE92742	PHH	Human	24h	10uM	EID0337

Response Information :

Types	Number	Response transcription factors
Up-regulation	149	MXI1; FOXN3; NFE2L1; HMGB2; HDAC5; PIAS4; MDM4; ARID1A; TWIST1; CEBPA; MYCN; TXNIP; TBX2; ZNF239; ZSCAN9; IRF9; SHOX2; TFAP2A; ZNF500; TLX1; CERS4; SMARCC2; DDIT3; SSBP3; HLX; TBX21; SOX2; DNMT1; TAL1; HOXB6; KDM5B; HOXB2; JUN; E4F1; FOXL2; SALL1; MLXIP; ZNF91; ESRRG; ZNF93; GLI3; CALCOCO1; CDK7; NFE2; ZNF580; ZFP36L2; ZNF177; MEIS1; ZNF652; KLF3; ZBTB16; ZNF688; BNC1; PRDM1; IKZF1; EZH1; PEX14; WNT4; DLX5; TRPS1; GATA6; ZNF263; ZNF510; AFF1; RBL2; ZSCAN32; HOXA11; ZNF667; DBP; PTRF; PAWR; CTBP2; ZNF556; TCF7L1; PBX1; ZNF202; NR5A2; LHX2; ZSCAN18; ZNF516; SIM2; ID4; MSX1; DLX2; CDIP1; TGFB1I1; HOXB5; HOXC8; THRA; KLF1; LHX3; ARNTL; DAXX; ZNF175; PEG3; KLF7; ZNF711; POLR3C; OSR2; ZNF43; INSR; CREB3L1; ATN1; BTG1; ZMYND8; SOX17; NCOA1; KLF4; SSBP2; FOXF2; KAT2B; PBX3; SMARCA1; KLF6; RERE; CD3D; PHF1; ERBB4; ESR1; ZNF232; ARID5B; MYBL1; ZNF586; E2F2; TCF21; NR2E1; PBXIP1; MAZ; MYB; STAT4; CITED2; SERTAD2; FOXD1; ZNF131; RFX5; WT1; ZNF107; SATB1; KLF9; CREB3L2; AEBP1; ZEB1; FOXE1; TBX3; FOXC1; BASP1; NFIC; RXRA; ZMIZ1
Down-regulation	131	EZH2; CCNA2; MTF2; MYCBP; AHR; USP22; SREBF1; SMARCA5; NUP62; UBE2I; TRIM28; BCL6; IKBKAP; RBBP4; DR1; NEDD8; ENY2; SFPQ; KAT6B; ZNF146; CCNC; FOXO4; XBP1; MLXIPL; NPM1; SNIP1; HLTF; VEZF1; NR1H3; MED7; PBRM1; ITGB3BP; RBM14; HOXA7; PIAS2; CRK; CHD8; MED4; NFAT5; NRIP1; MTDH; ORC2; RLF; C1QBP; HOXA5; UBE3A; RNF14; WWC1; BBX; E2F3; PLAGL1; CTNNB1; ATF2; C1D; TDP2; ELF3; CBFB; STAT3; TCF12; HLF; ZBTB38; TSC22D1; CHD1; SOX10; HSF2; BCL3; NR1I2; MAGED1; NR1H4; ZBTB20; HSBP1; COPS2; MAX; ATF3; NCOR1; CBX3; NCOA4; ZBTB14; YBX1; TRIM29; PCBD1; EGR3; NAB1; NR0B1; ATF1; MITF; ASH2L; FOXA1; ZNF12; ZNF423; NKX3-1; ZEB2; TLE4; BMI1; PUF60; LEF1; TFAM; REPIN1; RNF111; MEF2C; TCERG1; VGLL4; TBL1XR1; ZBTB1; NRBF2; BIRC2; HDAC1; BAZ1A; EYA1; UBP1; RUNX1; CHD4; HIRA; E2F5; TFEC; ILF2; IRF8; NFIB; TOX; DACH1; CARHSP1; EHF; INSM1; MED1; STAT1; ZIC1; TRIM22; KDM5D; TOX3; MAF; ID1