Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59833	Safinamide	GSE92742	PHH	Human	24h	10uM	EID0336

Response Information :

Types	Number	Response transcription factors
Up-regulation	69	HSF2; ADNP2; SSX1; HOXB6; LOXL2; GATA6; BACH1; TFAM; SP100; ELF4; PBX3; AATF; NKRF; PCGF2; TWIST1; NCOR1; LMCD1; AFF1; YWHAB; MAGED1; ASXL1; HIPK3; ZNF217; FHL2; HOXB2; GATA3; KLF9; KAT2B; HMGB3; ZNF593; NFIB; CHD1; ZNF264; SOHLH2; DDIT3; RBL2; TEAD1; BASP1; ZNF587; IKBKAP; MYBL2; TXNIP; HOXB5; SAP30; CTNNB1; CCNE1; CHD7; IRF8; IRF9; TLE4; LITAF; CITED1; ZBTB18; ATF3; POU2AF1; MITF; TRIM22; ARID5B; VDR; CEBPD; CDK2; MAFB; ZNF91; ZNF586; MAF; ERBB4; NKX3-1; AHR; SSBP2
Down-regulation	81	KAT6B; MTF2; SIX2; REST; RBPJ; NPAS2; PSIP1; MTF1; NANOG; RUNX1; PLAGL1; IL16; ZNF146; TEAD3; POU5F1B; MED20; DLX5; TBL1X; RUNX3; GLI2; CRYM; RBFOX2; SIX1; JUNB; INSM1; TULP3; GTF2I; BCL3; TCF12; ATF4; ELF5; NR2F6; CHD9; CREM; REPIN1; COPS5; MYCBP; NKX2-2; PEG3; MSX1; EZH2; FOXL2; AES; E2F5; ST18; NR0B1; ING4; CDYL; IRF1; TOX3; ERG; ZIC1; PITX1; EHF; CSDE1; TCF7L1; WWTR1; CCNA2; SOX17; CREB3L2; SOX11; FOXG1; TEAD4; IFI16; FOSB; SIM2; USP22; APEX1; ID4; MTDH; NR1H2; TCF21; KDM5D; UBE2I; RBPMS; CREB1; ASCL1; MECOM; ID1; BHLHE41; DAXX