Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59791	Flupirtine	GSE92742	PHH	Human	24h	10uM	EID0336

Response Information :

Types	Number	Response transcription factors
Up-regulation	174	NFKB2; SOX2; IKZF1; SIAH2; SAP130; TSC22D3; TRIM32; ZBTB17; FOXD1; TLE4; ETV1; RFX5; NFKB1; ZFHX4; TRIM16; ZNF200; TBL1X; HDGF; MEIS1; MAGED1; ZSCAN32; FOSL1; PKNOX1; MKL1; E2F6; IKBKAP; KAT5; ERCC3; UIMC1; GTF3A; ELF1; TOX4; ZBTB18; RNF4; SREBF2; CREB3L1; SIRT7; ZNF671; ZNF263; RREB1; IRX5; DAXX; SFMBT1; PHOX2B; NR0B1; GTF2F1; ZNF189; PIAS4; YY1; IRF9; HMGN3; ARID3A; CDK9; SATB1; MEF2D; NR3C1; ZNF415; HR; HOXC5; SP140L; TXNIP; HOXC4; ZNF93; ETV4; SP110; NPM1; ZKSCAN7; CBX4; MAX; TAF4B; ZBTB43; NAB2; ARHGAP35; ATF7IP; GLI3; SOX10; EVX1; ETV5; GTF2I; SALL1; ZBED1; ERBB4; TBX21; HOXA1; ZNF117; TRIM27; REL; MXD4; ZNF354A; ABT1; CCNC; TAF12; HMG20B; JUP; PRDM10; RNF141; SCMH1; ZNF124; KAT2B; STAT2; RFC1; CDK7; ZNF587; DMTF1; NR2F2; EDF1; TRIM29; ZNF423; SP3; TFAP2C; KLF2; ZFP64; PITX1; CDYL; VEZF1; STAT4; RHOA; ZNF711; MYCN; TWIST1; MED24; PHF1; MYBL1; AES; ARNTL2; IRF4; FOSL2; ING2; BCL11A; CNOT6; PIAS3; FOXC1; HMGA1; ZNF419; OLIG2; IRF2; ZNF264; SRCAP; ZNF544; CREB5; HAND1; ZNF721; NKX2-2; ZNF593; PCBD1; ZNF430; WT1; PEG3; NKX3-1; BTF3; ATF5; APEX1; CARHSP1; ZNF589; ZNF83; ZNF91; MNDA; ZNF512B; HOXB2; ZNF266; CCNH; SAP30; ZNF611; ENO1; ZNF586; TRIM22; CTNNB1; ARID5B; ESR1; ZFP36L1; MEF2C; ZNF160; AEBP1; KDM5D
Down-regulation	163	TERF1; NFIB; ASH2L; FOXO1; MED1; TFAM; ZNF155; KAT6B; MTF2; NFE2L1; PSIP1; MYCBP; USP22; TCF7L2; EGR2; PPARGC1A; ZNF302; NR4A1; SUPT5H; EED; PA2G4; ZNF131; MED14; CAPN15; ENY2; ZNF576; HEY1; XRCC6; CBFB; TOB1; TSC22D1; ATF3; BNC2; BCOR; RBPJ; ZNF146; UBE2L3; SMARCC2; SPI1; MAFF; STAT5A; HDAC9; RUVBL2; PRKDC; EMX2; EHF; ERG; CDX2; IL16; ETS2; CRY1; CBX5; SALL2; ID1; INSM1; JUNB; MED13; CREM; NR1D2; ORC2; ZEB1; ZNF770; ZNF140; ZMYND11; RBBP4; PTRF; PIAS1; WWP1; TBX1; NCOA2; ZIC1; NR1I2; PATZ1; NCOR2; RAD21; KLF9; BIRC2; ABL1; CCNA2; CREBL2; KAT2A; SOX15; CNOT3; ELF5; ZNF331; TULP3; TRPS1; ZNF32; BCL3; HOXA5; EZH2; IRX4; UBE3A; HSBP1; CNOT1; TFCP2; CCDC59; FOSB; PROX1; ZBTB20; WWTR1; COPS5; NANOG; CBFA2T2; NR1H3; CHD4; TOPORS; KDM5C; NKX2-1; NFE2L3; HBP1; MTDH; MITF; ZNF529; DEK; TGIF1; NR1H2; E2F3; ZNF3; TFEB; LITAF; ZNF22; ZKSCAN1; ZNF432; KMT2B; NR3C2; SMARCA2; ZBTB16; SOX17; PITX2; ASCL1; ZMYND8; MECOM; TRIP6; LMCD1; ACTL6A; ELK3; PMS1; MLXIP; UBE2I; REPIN1; SPDEF; BHLHE41; NFATC4; SOX13; CNOT2; SMAD1; ID3; ATF2; THAP11; TFCP2L1; MAF; CALR; JUN; SSBP2; ZMIZ1; STAT6; NR2F1; VPS72; CTBP2; MYB; AHR; TP53