Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59768	Lithocholic-acid	GSE92742	PHH	Human	24h	10uM	EID0336

Response Information :

Types	Number	Response transcription factors
Up-regulation	149	MTA1; E2F2; RFX5; RELB; SP2; USP21; GTF3A; HDGF; RBPJ; FOXD1; CRYM; RFX7; MAZ; ERCC2; SIAH2; MAFG; HDAC5; ARID5A; KAT5; SUB1; RELA; SREBF2; PDLIM1; SKI; ZNF771; SFMBT1; E4F1; NR3C1; TSC22D2; RCOR1; PAX8; MNT; KLF1; CDK8; CREG1; ZBTB18; MED24; CENPB; FOXO3; ETV5; BASP1; ZNF410; HDAC4; ESRRA; KLF12; RNF10; YWHAB; ZHX3; ZNF358; HMGB1; CARM1; ZHX2; IRF8; DRAP1; BRD4; ZNF580; ZBTB24; RUNX3; TEAD3; TRIM32; ZNF8; TBX21; ELF1; ZFHX3; CDK7; ZNF281; KDM5D; STAT4; NKX3-1; HIPK3; NCOR1; HMG20B; TXNIP; ZNF423; SALL1; CEBPA; MEIS1; MDM4; CDK9; PMF1; TOPORS; PCGF1; AFF1; CUX2; ZMYM2; CALCOCO1; ZMIZ2; MEF2D; NFKBIA; PHF1; CREB5; GABPB1; TSC22D1; PCBD1; NFYC; RORA; CRY1; MAGED1; ATF4; DDX17; MYRF; EWSR1; YBX1; BAZ2B; SMAD3; FOSL2; HOXB2; ABL1; APEX1; ZNF354A; MXI1; KAT7; NRBF2; NR0B1; OLIG2; SCAND1; ARID1A; ID2; BTF3; TGFB1I1; ESR1; ZMYND8; TRIM16; CD3D; IRF2; SMAD1; IKBKAP; MLXIP; ATF5; MYCN; NFATC3; CREB3L1; FOXO4; SSBP3; KAT2B; ENO1; NFKBIB; JUND; HMGA1; TWIST1; WWC1; WT1; TRIP6; CITED2; ZFP36L1; ZFP36L2; PSMD9; HMGB2; MSX1
Down-regulation	143	MTF2; MYF6; E2F8; ASH2L; ST18; PHIP; PSIP1; TCEA1; KAT6B; RNF111; SMARCD3; ZNF816; TRPS1; HHEX; SSX1; ZNF302; INSM1; PLAGL1; EN2; TOX; NKX2-1; HIC2; RBBP4; MYBL1; PITX2; ZNF665; NR3C2; ATF1; BCL10; JUP; ZFP30; ZNF426; NEUROD1; ZNF652; CCNC; ASCL1; NFIB; ERG; HSBP1; HES1; PPARGC1A; PIAS1; KDM5C; ID3; PAX6; EZH2; ZNF654; TBX1; HIRA; BNC2; PMS1; SOX9; E2F3; EPAS1; NR4A1; DLX5; HOXA5; ZNF146; HEY1; ZNF528; ZNF623; ENY2; HOXA1; ISL1; ZNF430; SND1; CBFA2T2; CERS6; TP63; CCNA2; ZEB1; CREBL2; ZNF107; PFDN5; SPDEF; CREM; MYCBP; PCGF3; COPS2; LOXL2; CNOT2; ZNF264; RUVBL2; FOXE1; TBX3; TULP3; RBBP8; RAD21; ZZZ3; RNF138; JUNB; NANOG; URI1; TULP4; VPS72; ETS2; ARNTL2; ITGB3BP; TRIM22; NFATC4; NFE2L3; HOXD1; CCNE1; ETS1; MECOM; ZNF573; MYBL2; RREB1; TCFL5; PRRX1; ZKSCAN1; ZNF532; KLF5; MNAT1; ZSCAN18; IRF4; USP22; FLI1; ZNF467; EHF; PRKDC; ID1; KLF2; MEF2C; CREB3L2; SIX1; SOX17; ATF3; SMARCA1; PEG3; ERBB4; NR2F1; JUN; MYCL; ID4; DLX2; WWTR1; PBX1; ZBTB20; AHR; GATA3; SSBP2; ZNF586