Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59750	Withaferin-a	GSE92742	PHH	Human	24h	10uM	EID0336

Response Information :

Types	Number	Response transcription factors
Up-regulation	133	E2F2; SIX2; RELB; FOXJ3; GTF2IRD1; IKZF1; RELA; VGLL4; FOSL1; SMAD7; CRYM; HOXB1; SNAI1; HMGXB3; DMTF1; FOXD1; MECP2; ELF4; FOXA1; ATF3; LOXL2; DRAP1; KLF12; HOXC4; HOXC5; EN2; KLF15; TAF7; AFF2; NCOR1; NFIC; SPIB; SMAD4; HOXC11; SOX10; MYBBP1A; CITED1; ZNF444; FUBP1; ZHX2; ZNF24; LPIN2; HIVEP3; LITAF; YBX2; ZNF423; ETV6; BCL3; NFIB; SFMBT1; HOXC10; MED17; NPAS2; TCF3; TGFB1I1; SMAD2; RERE; TSC22D1; NKX2-1; CCNT1; ASXL1; TRIM29; FHL2; DDIT3; STAT4; AR; KDM5C; MAFF; RNF138; HBP1; BRD8; NONO; HSBP1; TCF7; CREB3L1; NR4A1; PHF20; TERF2; CHD7; BTG1; MNAT1; TBX21; ACTL6A; SALL2; IRX5; TBL1XR1; HMGA1; RUVBL1; HMGN3; MAX; MAZ; GATA2; MYBL2; VPS72; IRF7; CTNNB1; ZBTB18; IRF2; PAX5; SMAD3; TBX3; ARID5B; DLX2; RFX5; ZNF532; ST18; RBBP8; MXI1; ZNF580; TXNIP; BASP1; CDK2; ZSCAN18; TGIF1; TP63; SOX9; THRA; TLE2; VDR; MBD2; KAT2B; ZNF586; NFAT5; NKX3-1; NR2F1; TRIM22; BCL6; HOXB2; PITX1; STAT6; CTBP2; LEF1; ZMIZ1
Down-regulation	126	TCEA2; TLE1; NFE2L1; PRPF6; ZNF512B; LIN28A; NANOG; CARM1; YWHAB; KLF6; ZNF426; MED1; COPS2; HOXA7; CDK8; IKBKAP; NFKBIA; ZNF652; ZNF146; SREBF2; E2F3; COPS5; NR1H2; SOX17; SREBF1; KLF11; PIR; UBE3A; FOXO4; C1D; NCOA2; NR1H4; PLAGL1; PGR; BMI1; CEBPG; PBX1; CREG1; NR1D2; NKX2-2; DEAF1; ZNF33B; ZNF165; SOX3; SMARCA5; RBPJ; MAF; SAP18; ZNF302; RORA; TRIM27; PCGF1; MED7; KMT2B; SUPT3H; HIC2; HOXA5; CAMTA1; HOXB7; ZNF268; MECOM; ZZZ3; ID1; CCDC59; TSC22D2; HLF; RREB1; MYRF; ISL1; TCF7L1; TFDP2; WNT4; ZNF562; PQBP1; ZNF264; BHLHE41; ZXDC; CCNE1; ZMYM2; CSDE1; BCL11A; ZBTB38; CEBPD; ETS2; CTR9; EHMT2; FOSL2; PMS1; ZNF131; SMARCE1; TLE4; PEG3; REL; TOX; URI1; FLNA; YEATS4; MAGED1; KLF4; ZNF331; EGR3; TCEB2; KLF5; ID4; NRBF2; RLF; SALL1; SOX11; MNDA; KDM5D; EMX2; WWTR1; JARID2; RBPMS; ZFP36L2; CCNA2; ZIC1; CREB1; ARID1A; HMG20B; RYBP; MEF2C; DAXX; MSX1; TOX3; DACH1