Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59717	Azd-6482	GSE92742	PHH	Human	24h	10uM	EID0336

Response Information :

Types	Number	Response transcription factors
Up-regulation	105	HDGF; FOXD1; GTF3A; HOXB6; GCFC2; GATA6; AATF; ZSCAN5A; HIPK3; MYBL2; PKNOX1; NR3C1; MAZ; ZBTB39; MYRF; NONO; ETV4; IRF5; LPIN2; DNAJC2; ELF2; ETV5; PIR; PBX3; HR; SOX9; RFX5; ZNF580; HOXB7; ZBTB18; JAK2; TFEC; HDAC4; JUP; SIM1; KLF12; RELB; SIAH2; PCBD1; PCGF2; HMG20B; MAGED1; HOXC4; HMGA1; NKX3-1; RBBP7; DAXX; ZNF423; SP2; POU4F1; TRIM32; HOXC10; KAT2B; GABPA; BRD8; IKBKAP; NPM1; SSBP2; MAFB; ZNF217; SRF; NCOA1; CNOT6; BRD2; RNF10; SMAD6; ESRRA; ZNF394; TWIST1; FOSL2; SFMBT1; ZNF384; EN1; NFE2L3; HOXB2; TBL1XR1; TEAD4; PHF1; AFF1; CREB3L1; SAP30; CDK2; ERF; NFKBIA; PSMD9; ARID5B; ZNF266; SERTAD2; BCL6; SSBP3; OSR2; HOXA1; RXRA; NCOR2; ZNF586; EGR3; KLF5; TGFB1I1; ENO1; NR2F1; WT1; TXNIP; DLX2; MNDA; ATF5
Down-regulation	103	PSMC3; ZBTB38; CBFA2T3; BACH2; ZNF131; ETS1; ZNF652; RUNX1; PPARD; ENY2; ZNF721; ZNF692; ZNF665; IL16; NR1D2; BCL10; GTF2A2; MYCBP; EHF; PGR; IFI16; PBX1; ELF5; NR2F6; BNC2; RARA; MED13; POU5F1B; HSBP1; TCEA2; ZNF146; UBE2L3; NR4A1; ZEB1; ID1; ZNF611; EZH2; CSDE1; WWP1; IRX4; TULP4; PTRF; ZNF432; CRK; PSIP1; ZNF160; NANOG; ASCL1; ZNF224; BASP1; NR1H2; SOX11; CCNA2; KLF4; CREB3L2; SOX13; TSC22D2; NRIP1; TOX; KMT2B; ZNF573; HTATIP2; HDAC9; ZNF426; ZSCAN18; KDM5B; SMARCB1; BIRC2; CNOT2; TCF21; HEY1; TCF7L1; MEF2C; PEG3; RYBP; RBM39; TULP3; MYB; CREB1; FOSB; SALL2; ABL1; PRKDC; TP63; ID3; INSM1; BCL11A; PAX5; MTF2; ZNF83; ZBTB20; SOX17; PDLIM1; NR4A2; HOXD1; HHEX; HOXA5; JUN; TBX3; ZMIZ1; MSX1; AHR; VPS72