Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59715	Motesanib	GSE92742	PHH	Human	24h	10uM	EID0336

Response Information :

Types	Number	Response transcription factors
Up-regulation	178	MTA1; HSF2; RELB; ATF6; NEDD8; PMF1; NCOR2; ZFHX4; MAFG; ARID5A; NKX2-2; CDK7; NFIC; MYC; PDLIM1; SUB1; BHLHE40; DDX54; SP140L; GTF3A; NR3C1; DRAP1; SNIP1; PAX8; ERCC2; ZNF614; SP1; NACA; KAT5; SIAH2; BRF2; MDFI; TLE1; ZNF35; ZNF552; AATF; SP110; HDGF; CDK9; NR0B1; YY1; SP2; ELF4; ZNF646; CENPB; RHOA; ERF; RBBP7; APBB1; KLF13; SREBF2; ELF2; PCBD1; NFKBIA; THAP10; RARA; HDAC4; BATF3; EMX2; NR1D2; ZFP37; GATA6; ZHX2; OLIG2; ZNF10; HABP4; HR; MED24; ZKSCAN7; KAT7; SMAD6; ARID4B; ALX1; CREB5; ZEB2; THAP7; ABT1; ZNF580; BTF3; ZNF358; SPIB; KLF2; ZNF292; TRIM25; HOXC5; MLXIPL; KLF11; SIRT7; IKBKAP; BACH1; CCNC; HIPK3; MEIS1; PBX2; AES; MAZ; BCL6; KAT8; ZNF8; NKX3-1; ATF4; SALL1; ZNF593; RNF141; ETV5; ZNF212; BCL3; SMAD7; CEBPA; EP300; HDAC9; SFMBT1; IRF3; PCGF2; IRF9; TWIST1; C1D; ZMIZ2; SMAD3; ESR1; KAT2B; SCAND1; MEF2D; RXRA; ZNF468; MEOX1; EYA1; ZNF671; NR1I3; MED21; TGFB1I1; ASXL1; MEF2A; ZNF281; RING1; OVOL2; BATF; DDIT3; KLF7; TRIM16; AIP; YEATS2; TAF10; CNBP; TXNIP; ZNF384; HOXC10; PHF1; HOXA11; BRD4; SRCAP; MITF; SATB1; APEX1; DDX17; PITX1; SERTAD2; FOSL2; ZNF443; ATF5; MYRF; MKL2; CREB3L1; MAFB; PSMD9; CCDC59; MYCN; JUND; NFATC3; BRD2; SOX9; ZBTB18; FOXC1; THAP11; AHR; STAT6; ZNF586; TP53
Down-regulation	198	SPEN; TERF1; SUZ12; MYBL1; VGLL4; GTF2A2; BTAF1; CRK; IFI16; RNF138; REST; FOXO1; NFX1; TCF7L2; TAL1; TRIM24; RAD21; ETS1; ZNF146; RNF111; PIAS1; CBFA2T3; MYCBP; URI1; BRCA1; HLTF; WWTR1; CDK8; TGIF2; KLF6; CBFA2T2; ZNF232; HIC2; ZNF248; SMAD1; ENY2; USP22; SOX15; EZH2; SUPT5H; SOX2; DYRK1B; ZEB1; TFDP1; FOXN3; NR3C2; FUBP1; ARNTL; HMGA2; MMS19; ADNP; CREB3L2; TULP4; TBL1X; ING1; MYB; HIPK1; TCF7L1; PAWR; NR2F6; NANOG; HIRA; INSM1; MEN1; EN2; MBD2; TCF21; TDRD3; ERG; DACH1; REPIN1; CBX5; BRIP1; SMARCA5; PTRF; TRRAP; EPAS1; CEBPD; COPS5; KMT2B; NR5A2; ZNF302; UBE2L3; ZNF24; ID3; BMI1; PPARD; PLAGL1; AEBP1; RREB1; ZNF721; BCL10; MTF2; ELF5; PBX1; CREB1; CBFB; MXI1; HHEX; CHD7; ZNF131; WWP1; TDP2; FOXJ1; CXXC1; PPRC1; KLF5; MED12; RUVBL2; CNOT6; HIVEP1; ARL2BP; YAP1; ZNF264; E2F3; BRD7; MDM2; ZZZ3; ZNF623; ZNF107; ST18; TERF2; HSBP1; TRIM27; SMAD4; FOSB; ZMYND8; ZNF177; NR2F1; ZNF160; BAZ2A; PEX14; RNF6; CDIP1; CENPF; ITGB3BP; ZKSCAN1; TRIP6; MYBL2; NFE2L2; NFE2L3; CSDE1; SFPQ; CAMTA1; ZNF652; CCNE1; TULP3; CTBP2; PCGF3; ZNF224; EHF; BIRC2; PBX3; ELK3; ZNF611; TCEA2; PEG3; SALL2; MNAT1; ZNF562; CNOT2; POU2AF1; PRDM2; JUN; SIX1; ZBED2; ERBB4; TOX; NFE2; NR4A2; ZNF573; MTDH; ZSCAN18; TSC22D2; ZNF165; SOX11; TFCP2L1; JARID2; GATA2; DLX2; RUNX3; TFAP2C; RNF14; NR1H2; NR2F2; HMG20B; JUNB; MAFF; CD3D; CITED2; CCNA2; TRPS1; GATA3; MECOM; HEY1; HMGB3; HMGB2; DAXX