Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59693	Safinamide	GSE92742	PHH	Human	24h	10uM	EID0335

Response Information :

Types	Number	Response transcription factors
Up-regulation	108	ECD; ACTL6B; ESR1; VPS72; JUP; SMARCD3; RFXANK; LHX3; CDX1; TTF2; IRF9; DACH1; BCL11A; ZNF22; MDM4; NEUROG1; HOXC8; CSDC2; EYA2; MYBL2; NCOA3; ASXL1; ZNF354A; ZNF345; STAT1; NEUROD6; PCGF3; TAF11; RBL2; DBP; RFX2; CDX2; FEV; NHLH2; ZNF331; CDC5L; SNAI1; SSX3; ZNF85; ZNF117; PEX14; FLI1; DDIT3; IFI16; SOX13; BRIP1; USP16; RARA; CBFA2T2; GATA6; FOXA2; TAL1; HIPK3; NCOA1; ZNF202; EMX2; MEIS1; MYT1; ESRRG; HOXD3; SSBP3; KDM5C; MLX; HLX; RBFOX2; HOXA11; RXRA; IRF6; ZNF266; HOXD1; TFEB; PCGF2; ZFP36L2; HDGF; PAX5; ZNF43; THAP10; CTBP1; HOXB2; DMTF1; CALR; TAF5; TWIST1; WT1; ZNF415; HOXB13; NR3C1; HDAC9; SOX17; TFAP2C; BACH2; MXI1; NFE2; HMGB1; ZNF93; MKL2; MEF2C; CRYM; ST18; POU2AF1; ZNF91; OSR2; IRF4; LEF1; CHD7; TCEA2; ERBB4; TFAP2A
Down-regulation	173	ATF5; NFIB; CBX5; AFF1; MTDH; FLNA; ENY2; EZH2; PTRF; DR1; TFDP2; KLF5; SMARCA5; DDX5; TCEA1; HIRA; REXO4; CEBPG; DNAJC1; ZNF23; HSBP1; ELF5; CCNA2; MYCBP; MITF; PRRX1; ZXDC; MED13; WWTR1; NCOR2; VGLL4; GABPB1; MTF2; KLF10; NR2F2; DNMT3B; ING1; TAF12; CENPB; NCOA4; KMT5A; COPS2; EDF1; HEY1; MTF1; SAFB2; TOX3; NR1H2; ZBTB18; KLF2; STAT5A; ZBTB38; BAZ1A; CCNC; TFE3; CRK; E2F5; EP300; NELFB; BAZ1B; CEBPB; AHR; TFCP2L1; ID1; LPIN2; NANOG; MAGED1; DEK; NFKBIA; REPIN1; SFPQ; BTG1; HMGN3; ZNF281; THAP11; TCEB2; ING2; ADNP2; ZNF551; CNBP; RAN; ETS2; ZNF146; ARID4A; SAP30; YBX1; NRBF2; LIN28A; ERBB2; HDAC1; NFE2L1; ZNF688; ZNF148; RBBP7; RUVBL2; ATF4; HES1; ZNF787; ZNF654; TAF10; HMG20B; FUBP1; ARNTL2; HTATIP2; TFEC; MDM2; USF2; WWC1; BIRC2; SMAD1; HLF; C1QBP; RBPMS; CBFB; FOSB; CREBL2; KLF4; TRIM16; ZNF329; UBE2I; PQBP1; TP53; ZBTB16; ZNF264; FOXO4; RFX5; RBM14; SPEN; NR1H3; FHL2; ZNF423; JARID2; KDM5D; MAFG; ENO1; UBP1; TDRD3; MAF; IRF1; TRIM28; TRIP6; IRF2; FOS; RCOR3; MAFB; NR4A1; NEDD8; AEBP1; USP22; TRIM22; ERG; BCL3; NKX3-1; ID2; TADA3; ID3; ATF3; KAT6B; FOXG1; KLF6; CREB1; PIR; TOB1; ZNF586; PEG3; SATB2; EGR3; NR2F1; CITED2; EGR2; ZMIZ1; SIX1; EGR1