Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59691	Vx-745	GSE92742	PHH	Human	24h	10uM	EID0335

Response Information :

Types	Number	Response transcription factors
Up-regulation	213	TCFL5; KDM5B; NFYB; VDR; MYB; GRHL2; TCF7L1; KDM4C; MLLT10; LHX3; FOXC1; ETV6; OSR2; TFDP2; LDB1; TTF2; HMGB2; BATF; EYA1; SOHLH2; IRF6; ZNF354A; HOXC13; ZNF423; SNAPC4; HOXC4; KLF13; EBF2; SSBP3; PITX2; DDIT3; ZNF117; BACH1; YEATS4; INSR; SMARCD2; ERBB4; IRF5; MYCL; NCOA1; IRF9; FOXE1; RELB; E2F4; JUP; PAXBP1; MED12; BANP; EP300; FOXN3; ZNF536; ZNF281; TERF2; SUZ12; TLX1; MTA1; MYBL2; EWSR1; ELF4; TCF3; HOXD3; ZMYND11; SAP30; SAP130; SNAI1; HOXC11; ELF3; EP400; CBFA2T3; ZNF217; ZNF510; ZBTB24; BNC1; BACH2; TLE4; FUBP1; RNF138; FOXO3; GFI1; CDK9; URI1; SIAH2; KLF3; TCF7L2; HTATIP2; THAP10; MLXIP; MXI1; TFAP2C; ZSCAN18; HOXA11; SFMBT1; ZNF43; ZNF235; RFX2; HIPK1; TERF1; NCOA3; ESRRG; CHD7; ZNF200; FLI1; TRIM29; KLF1; ZNF350; KLF5; ZNF85; GATA6; ERBB2; BRCA1; HMGB3; RRN3; ZNF211; HMGA2; FOXI1; DLX2; ZSCAN32; WHSC1; TWIST1; ZBTB39; AEBP1; TBX2; CCNE1; KLF6; ZNF215; VPS72; ZBTB11; HMGN3; GTF2A2; TSC22D3; KLF9; LMCD1; RUNX3; ZFP36L2; WNT4; RARA; PAX6; ZIC1; NR3C2; SMARCD3; HLX; CSDE1; HOXB13; NFIC; DACH1; TCERG1; FHL2; SIX3; TULP4; THRA; AGO2; CTBP2; AATF; CTNNB1; ELK3; SOX11; SPEN; CITED2; ARID4B; IRF4; HOXB7; HHEX; TBX21; PLAG1; CUX1; SIM2; PBXIP1; TAF1A; ZNF415; DMTF1; ZHX2; NR3C1; E2F2; PCGF2; ZNF134; KLF4; ARID5B; NR4A2; SETDB1; RBL2; HOXB6; TAL1; PBX3; NCOA2; TP63; SMAD1; ZEB1; DAXX; RBBP8; ZNF586; ZNF93; STAT4; MEN1; SMAD2; BCL6; HOXC6; PAWR; FOSL2; HOXB2; MYT1L; CHD4; POU2AF1; ZNF91; ZBED2; SHOX2; NFE2L2; FOXD1; ZFPM2; NRIP1; WT1; ATF3; NR2F1; LEF1
Down-regulation	200	ZBTB38; MYC; COPS2; TLE1; PBRM1; SCAND1; NKX2-2; KAT2A; HLF; ZNF576; ETV5; ZNF721; MTF2; RLF; ZNF160; ZNF148; MYCBP; DR1; FLNA; ZNF528; FOXO4; RYBP; ZNF224; ZNF146; DEK; TOX3; EZH2; KMT2B; MTDH; PTRF; SND1; CCNA2; NFKBIA; FOXJ3; ZNF83; CREG1; PDLIM1; CREB5; LPIN2; CEBPA; NFIB; EDF1; CBX3; NCOA4; RBBP5; ZNF12; MAF; FEZF2; ZNF23; CENPB; YBX1; ZNF652; HEY1; GCM1; ENY2; NFAT5; BAZ1A; ZNF302; LZTS1; PIR; ID1; ELF5; DNAJC2; NPM1; TP53; RBBP7; REPIN1; BTG1; SUV39H1; MED23; KDM5D; PTTG1; PQBP1; PMF1; CREBL2; BHLHE41; DNAJC1; THAP11; CAPN15; SP110; ING3; TRIP6; CEBPB; TAF10; MBD2; TCEA1; SLC2A4RG; APEX1; GTF3A; NR1D2; TCEB2; PCBD1; NKX3-1; ETS2; NR2E1; ZNF611; SALL1; HSBP1; ZNF787; NR1I2; SP100; ZNF267; RBFOX2; BRD2; MLXIPL; FOXA2; KLF10; NCOR2; USF2; GATA4; NEDD8; TBP; PCGF1; RUVBL2; POU3F1; PEX2; MSX1; DDX17; RHOA; ZNF384; ZMYM2; ZNF189; POU5F1B; TBX1; BAZ1B; NANOG; SATB2; NR1H4; JUN; CBX4; KAT6A; AR; IKBKAP; BIRC2; MAZ; XRCC6; ZNF264; IRF8; RAN; CEBPZ; MED1; CHD8; TADA3; BRD8; ATF4; SREBF1; TBPL1; NUP62; NFE2L1; ZNF426; TDRD3; TBX3; TFEC; RORA; PROX1; PPARGC1A; NKX2-1; EGR3; KAT7; ID3; HOXA5; NR1H2; TSC22D1; LHX2; NRBF2; EMX2; SMARCA1; TBL1X; CALR; ZBTB20; MED21; ENO1; ZNF136; C1QBP; ZNF226; FOXA1; TLE2; FOSB; DRAP1; CUX2; CTR9; NFATC3; ZMIZ1; AES; USP22; MECOM; SIX1; UBP1; RBPJ; PLAGL1; FOXG1; ABL1; TRIM28; MEIS1; RFX5; SOX17; PEG3; TCF4; MAFB; EGR1