Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59678	Canertinib	GSE92742	PHH	Human	24h	10uM	EID0335

Response Information :

Types	Number	Response transcription factors
Up-regulation	86	DDIT3; GTF3A; BATF; NPAT; PKNOX2; RUNX1; SMAD3; NCOA3; HIVEP2; CRY1; SERTAD2; DBP; ATF5; ZNF302; IRF7; DDX17; ATF4; ZNF43; ZNF354A; KLF10; CDK8; BATF3; RXRA; FOS; ZNF184; EYA2; SOX11; SCAND1; CITED1; ZNF544; CEBPG; PLAG1; PBX3; TFAP2C; FOXC1; NFE2L1; DLX2; BASP1; ZNF589; ZFP36L2; SMARCA2; SMAD6; PIR; NFATC1; OSR2; CEBPD; YWHAB; ZNF586; BACH2; BIRC2; ZNF419; FUBP1; ZNF593; SPEN; NCOA2; ZNF85; PHF20; TRIM29; HOXD3; ZNF131; INSR; ZNF91; MKL2; NFE2; ZBTB18; GATA6; ZNF652; AEBP1; MXI1; ZNF93; SMAD2; ATF3; ABL1; SIX2; ENO1; WT1; ZNF606; MECOM; ERBB4; LMCD1; IRF4; TOB1; ZNF217; MAFB; ID4; TCEA2
Down-regulation	71	GABPB1; MTF2; CCNA2; CHD1; EZH2; MYCBP; SMAD4; NFAT5; ZNF124; ZBTB38; USP16; COPS2; TERF1; HES1; ITGB3BP; ENY2; TLE4; HSBP1; IKBKAP; UBE3A; KLF2; ISL1; TFAM; HIRA; TRIM22; ATF7IP; SUPT3H; SMAD7; HLF; ASCL1; MED23; PTTG1; CUX1; TCF4; UBP1; TULP4; ING3; ERG; PHOX2B; ESR1; JARID2; FOXF1; TBX3; PSIP1; PAX8; EGR2; HLTF; ID2; ZEB2; TLE2; TCERG1; PAX5; NEDD8; TFEC; TGFB1I1; RBPMS; DACH1; PLAGL1; KAT6B; TBL1XR1; INSM1; TCF12; HOXB7; EGR3; MLXIP; TGFB1; ST18; SOX9; NFATC3; EGR1; LEF1