Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59675	Nelfinavir	GSE92742	PHH	Human	24h	10uM	EID0335

Response Information :

Types	Number	Response transcription factors
Up-regulation	148	ESR1; NFKB2; OVOL2; ZNF45; GRHL2; TSC22D3; STAT2; ELK3; HOXA11; ORC2; NR1D2; ZBTB40; GATA3; TFCP2L1; ZNF473; ZNF267; ADNP2; EYA2; AEBP1; ZNF557; ZNF200; NKX2-1; POU4F1; CDX1; SP3; JUN; OSR2; FOXE1; NR3C2; ZNF652; AIP; ARRB1; ZBTB6; HIPK3; LHX6; PHOX2B; NR2E1; TTF2; NHLH2; HDAC1; MLLT10; ZNF273; ZNF184; BHLHE40; NR4A2; NCOA3; UBE2B; ARID1A; HIVEP3; REL; SNAI1; ZSCAN5A; MKL2; HHEX; TAF9B; PPARGC1A; KAT7; SMAD5; ZNF266; SFPQ; SAP130; LITAF; HOXC4; TCF7; CDK2; NFE2L3; TFAP2C; ZNF394; SATB1; NR2F2; FOXC1; SMAD2; ZBTB16; RBBP7; STAT6; FLI1; TERF2; DLX2; TOB1; SSX1; ZNF14; DDIT3; IFI16; BRCA1; AR; BCLAF1; PAX6; MED6; CALR; MED14; HIC2; DACH1; FOSL1; YWHAB; SMARCA4; ISL1; E2F8; ITGB3BP; TP63; ZNF331; SALL1; ZNF589; SMARCA2; KLF2; CREM; DNMT3B; NR0B1; ADRB2; BCL11B; KAT6B; KAT5; ZNF665; TGFB1I1; MECOM; BHLHE41; BMI1; LIMD1; RBPMS; ARID4B; TAF1A; SIAH2; TLE4; FOXA1; FLNA; ZBED2; CREB3L1; PFDN5; IRF6; ATF3; ABL1; TCF7L2; MEIS1; PAX5; PIR; SOX9; CRYM; BRD2; PBX1; ATF4; NR2F1; ZFP36L2; ELF1; ZMIZ1; TGFB1; MSX1; NRIP1; TFAP2A; LEF1
Down-regulation	133	ZIC1; ASCL1; ZNF83; EP300; SMARCD3; GFI1B; CCNE1; E2F3; MXD4; SCAND1; GATA1; ZNF576; NAB1; LHX5; BATF; KLF1; BARX1; CENPF; ZBTB38; HDAC2; NFE2; ZNF500; TSC22D4; SOX12; PREB; WHSC1; HCFC2; TEAD1; LHX1; TBP; NFAT5; NFIB; BAZ1A; ERF; HEY1; TFDP2; HOXC8; SLC2A4RG; HOXD3; TLX3; SMARCA5; MSC; MTDH; TRIP4; COPS2; ZMYM2; TCF15; ZBTB20; CREB5; ATF2; DRAP1; TRIP6; ZNF282; TP53; ZNF148; ZBTB25; HTATIP2; KLF12; FOXK2; ZNF529; RYBP; CAPN15; KAT2B; IRF7; GLI2; AFF1; CDYL; MTA2; YAP1; ZNF329; IRX4; POLR2A; HES1; BBX; LZTS1; RFX5; MED20; FOS; BCL3; HSBP1; TAL1; ZNF189; BIRC2; ZBTB7A; NR1H2; REPIN1; BAZ2B; TBL1XR1; WIZ; BCL6; FOXO3; NFIL3; POU5F1B; BRD3; ARID4A; XBP1; PDLIM1; ZNF593; NPM1; CBX6; AGO2; FOXO4; TAF10; CUX2; NRBF2; ZFHX4; ZNF562; CHD9; CHD8; JUND; C1D; BRD8; KLF6; TADA3; SSBP2; EZH2; HDGF; PEG3; PSIP1; TSC22D1; BRD4; NEDD8; HMG20B; ID3; CCNA2; ING3; SNAI2; RELB; PHIP; FOSB; ZNF586; EGR3; EGR1