Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59655	Gw-441756	GSE92742	PHH	Human	24h	10uM	EID0335

Response Information :

Types	Number	Response transcription factors
Up-regulation	131	ALX1; FOXN3; MXI1; HR; GATA3; ESR1; LHX3; CSDE1; NCOA1; EYA1; MDM4; SERTAD2; IRF9; FOXC1; GTF3A; PHF1; TRIP4; MYCN; DDX17; NCOA3; IRX5; RXRA; MED14; PEX14; ZNF544; GTF2A2; IRF7; ZNF175; ZEB1; ZNF354A; NHLH2; SETD3; NFE2; PCGF2; RBL2; NOC2L; TBX2; BACH2; CDIP1; RFXANK; ADNP2; WDR77; ARID1A; IFI16; BASP1; NCOA6; ZNF589; HOXA11; DDIT3; SUB1; MAFF; FOXE1; FOXF1; WHSC1; ZNF671; FLI1; TCEB2; HTATIP2; TAL1; ZNF573; ZKSCAN7; PBX3; SMAD3; DBP; GRHL2; TFAP2C; ZNF593; GATA6; NFKBIB; ZFHX4; KLF1; PRDM10; AIP; ZNF93; NFATC1; HLX; TCF7L2; HMGB2; TBL1X; ZFP36L2; HOXB6; BNC1; ERBB4; BRD3; JUND; LITAF; CUX2; SOX11; AEBP1; FOXD1; ZBED1; PAWR; ZNF43; ZNF117; PSMC3; MEIS1; ZMYM2; PIR; SOX9; REL; IRF6; MEOX2; IRF4; KLF6; ZNF652; ZNF586; ZNF91; ZNF331; ABL1; TFAP2A; TFDP1; KLF9; HDGF; LOXL2; SMAD2; ZNF606; ZSCAN18; ATF3; TGIF2; ID4; SMAD6; TWIST1; TCEA2; TBX3; PBX1; ZNF217; OSR2; TCF21; ID3; LMCD1; TXNIP
Down-regulation	136	EZH2; CRK; ENY2; GABPB1; DEK; CCNA2; PRRX1; CHD1; HLF; MTF2; UBE2B; ZIC1; PTTG1; BHLHE41; ETV5; PBRM1; TERF1; CBX5; NR1D2; SMARCE1; ETS2; FOXO4; REPIN1; ZNF148; XBP1; GMNN; MYCBP; ZNF267; INSM1; ARNTL2; SNIP1; ITGB3BP; PLAGL2; MTDH; MED15; STAT5A; CNOT2; HSBP1; CBX7; HDAC6; MED21; SFPQ; MED7; ZNF146; CEBPG; HLTF; USF2; KLF5; VEZF1; TMF1; TRIP6; TAF6; UBE3A; NRBF2; STAT5B; BCL10; COPS2; CAPN15; PEX2; NFKBIA; SMAD1; CENPB; BPTF; LPIN2; ZBTB38; RFX5; JARID2; MAGED1; KLF10; MEF2A; BAZ1B; ZEB2; CCNC; RBM14; ACTL6A; ZNF212; ZNF12; TCERG1; ARID4A; HES1; HEY1; TRIM22; HIC2; TFEC; E2F3; ING3; BRD8; EMX2; NFAT5; TCF4; FLNA; CD3D; NRIP1; SIX1; PSIP1; EGR3; CERS6; ERG; PCBD1; ATF1; CHD8; BBX; NR0B1; ELK3; NR1H3; TBL1XR1; NPM1; MLXIP; ID2; ZBTB20; MED1; ARID4B; TRIM28; MED6; ERBB2; NKX3-1; NEDD8; MEF2C; SNAI2; USP22; WWTR1; PAX8; MED24; C1QBP; SMAD7; FOXG1; PAX5; EGR2; PLAGL1; MAFB; ZBTB18; KAT6B; PITX1; IKBKAP; ZFPM2; EGR1