Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59619	7,8-dihydro-l-biopterin	GSE92742	PHH	Human	24h	10uM	EID0335

Response Information :

Types	Number	Response transcription factors
Up-regulation	116	PCGF2; SOX4; ITGB3BP; BACH1; KAT2A; ZNF124; MTA1; SMARCC1; HMGB3; BACH2; ZNF22; MYT1; CTNNB1; LYL1; SMARCA1; TRIM22; PAX5; ETV5; BLM; PIAS4; HSBP1; SHOX; ZNF146; AFF2; USP16; ABT1; HAND1; SREBF1; MYB; PRMT2; ZBTB24; SND1; MED1; SMAD5; MZF1; SCMH1; ZNF273; RHOA; TFEC; HOXB5; ASCL1; TOX3; CREB3L1; NR0B1; STAT6; PGR; ZNF552; HHEX; MAGED1; TERF2; RUNX1; BHLHE40; HOXC10; FLI1; FOXA2; CDK7; CITED1; AATF; SMAD2; HOXC4; SIAH2; RNF141; ZFHX4; KLF2; TAF1D; ZNF516; NFIL3; PIAS3; IRF6; MED24; ERG; SOX10; SAP30; MLXIP; CTBP2; PFDN5; NPM1; ZNF587; ZNF665; NFIC; ZNF85; ZMYM2; SIX3; HOXD1; ZNF721; RUVBL2; NFE2; AES; BCL11A; MECOM; HMGB1; MEN1; ZNF652; SMARCA4; ISL1; APEX1; TCF12; TGFB1I1; KDM5D; IRF8; HMG20B; PHIP; HOXB6; RFX5; ZBED2; CRYM; EZH2; ZNF532; ZSCAN18; POU2AF1; LEF1; IKBKAP; ZEB2; SIX1; ZNF586; TXNIP
Down-regulation	149	HNRNPD; ID1; KLF5; ALX1; ZXDC; CCNE1; SOHLH2; TEAD3; UBE3A; ZNF148; ZBTB43; HIVEP2; YAP1; BTAF1; CREBL2; WWTR1; HOXA4; SUPT5H; TAF11; THAP11; CRY1; MAF; JUND; ZSCAN12; DLX2; DEK; MTDH; HIPK1; THAP7; TEAD4; SOX9; FLNA; BRD4; NEUROD1; BCOR; POLR3F; ZSCAN16; TFE3; KMT2B; AFF1; CEBPB; KLF11; FOSB; HDAC2; PAX6; YEATS4; HEY1; TRIM29; ZNF217; CAPN15; HES1; REST; RORA; KLF9; ELF5; NFIB; ZNF573; ID4; ZIC1; ARNTL; ZNF165; ZNF562; PEX2; ZNF12; CENPB; ERBB2; POLR3C; MED15; CNBP; ZNF84; NCOA1; TCEA1; KDM2A; STAT3; PRPF6; ING3; CHD8; BRD2; SMAD6; HIRA; BHLHE41; EMX2; TOB1; TAF9B; PAWR; ARID4A; ZBTB38; SLC2A4RG; PURA; ARNTL2; EN1; TGFB1; TCF7; PHF20; RNF111; PNRC1; HMGB2; KLF10; HMGA1; LIN28A; NRBF2; KLF4; FOXG1; ZFP36L1; MEIS1; ZNF281; ZNF589; ZNF512B; FOS; NAB1; YWHAB; ABL1; REL; AHR; BCL3; MEOX2; SPEN; CITED2; DACH1; ZNF140; MXI1; ARID5B; GATAD2A; ID2; CCNH; GCFC2; C1QBP; CHD7; MYCL; TRPS1; TBL1X; ID3; CEBPD; DAXX; NRIP1; SSBP2; TFDP1; TBX2; ATF3; HOXB2; TFAP2A; RUNX3; PBX1; NR4A1; MAFB; CREB1; USP22; EGR3; EGR1