Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59615	Gw-501516	GSE92742	PHH	Human	24h	10uM	EID0335

Response Information :

Types	Number	Response transcription factors
Up-regulation	153	VPS72; ZNF83; ZNF22; LHX3; GATA1; NFATC4; KLF15; BACH2; STAT2; NFE2; SERTAD2; THRB; ACTL6B; IRF6; BARX1; PRDM14; AR; ATF3; DBP; NEUROD2; ZNF415; IRF7; JUN; ZNF354A; ZNF154; ZFP36L2; JUP; RXRA; IRX5; ZNF74; RARG; TAL1; FOXA2; SNAI1; NHLH2; RFXANK; THRA; ZNF85; EMX2; ZNF117; KLF13; SMAD3; WDR77; ZNF331; HIVEP2; NRL; FOXE1; NPAT; RFX2; CSDC2; ZNF141; ESR1; CUX2; GTF2A2; FLI1; EN1; HOXA11; HIPK2; NCOA1; RING1; BCL11A; KLF3; VGLL1; TTF2; FUBP1; HDAC5; NHLH1; MYBL2; STAT6; SALL2; RBL2; ERBB4; NFIX; ZNF43; MKL2; JUND; HOXB6; GMNN; DDIT3; ZNF215; SOX13; NR5A2; MYBL1; SSBP3; ZMIZ1; LOXL2; ZNF711; HOXB5; HOXB2; HHEX; TCFL5; DDX17; EZH1; TP73; SPDEF; PKNOX2; ZIC3; GATA4; MYCN; BNC1; ZNF239; ZBTB16; ZSCAN18; ZEB1; MXI1; MAFF; BRD3; ZNF266; CALR; RERE; LIN28A; GATA6; IRF9; ZNF91; LITAF; ESRRG; HOXC4; SETDB1; HDGF; RORA; OLIG2; PAWR; KLF11; ATN1; BRWD1; KLF9; NFATC1; FOXL2; MYRF; SPIB; NFIC; PBX3; TOB1; CDK2; PBXIP1; PFDN5; TCF7L2; CTBP2; ZNF586; DMTF1; ZNF93; IFI16; ZNF467; AEBP1; OSR2; ELK3; LMCD1; ST18; ZNF589; WT1; IRF4; PBX1; ID4
Down-regulation	173	CRK; ZBTB38; ENY2; DNAJC1; EZH2; MTDH; KLF5; SFPQ; ZNF146; NR2F2; FOXO4; ETV5; CCNA2; ZNF160; NR1D2; ZNF528; XBP1; GABPB1; RNF10; WWP1; TERF1; FLNA; BHLHE41; REPIN1; ZNF148; HDAC1; HLF; UBE3A; MED4; ID1; MYCBP; PRRX1; SCAND1; SMAD4; PBRM1; ETS2; AHR; TRIP6; HEY1; SMARCE1; PTTG1; SP3; NFIB; UBE2B; MED7; UBP1; MITF; USF2; PEX2; CNOT2; ZNF576; C1D; C1QBP; MAF; BMI1; IRF8; CBX7; ZMYND11; NCOR2; TFDP2; BAZ1B; HMGA1; ATF5; ING1; TRIM22; TRIM28; SAFB2; RBPMS; MED23; RBBP5; MBD2; ARID4A; ZNF721; SP2; HMGN3; TMF1; MED6; SNW1; KLF2; KMT2A; TAF11; RBM14; ASH2L; TGS1; ADNP; NKX3-1; NR1I2; BBX; NRBF2; MTF2; USP22; RNF6; NR2F1; TBL1X; EDF1; SP100; SUB1; TBPL1; SAP18; ZFP64; WWTR1; NFYC; NEDD8; ATF1; RFX5; LZTS1; BAZ2B; NCOA4; SKI; PQBP1; CREBL2; ZEB2; TCERG1; PLAGL2; MDM2; ISL1; TFEC; SIX1; MECOM; CARM1; SOX9; TP53; ING3; CTR9; ARNTL; TAF10; TADA3; KAT6B; MAX; PLAGL1; BIRC2; RAN; FOXG1; CERS6; ID2; TSC22D1; PHF8; ABL1; CARHSP1; AES; SMARCA2; HTATIP2; INSM1; DAXX; EHF; PIAS2; CREB1; CBFB; BCL3; PIR; ELF5; CITED1; ERG; TGFB1; ZNF468; BASP1; PSIP1; MAZ; HDAC4; RUNX3; NR4A1; EGR2; EGR3; FOSB; ZBTB18; SIX2; NRIP1; MSX1; MAFB; MED1; TCF4; EGR1; SMARCD2