Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59612	Celastrol	GSE92742	PHH	Human	24h	10uM	EID0335

Response Information :

Types	Number	Response transcription factors
Up-regulation	99	E2F2; MYBL1; SUZ12; MYBL2; SOHLH2; TAL1; HMGXB4; MYB; ESR1; MXI1; NCOA1; HINFP; VPS72; SOX12; TAF12; HMGB3; NR5A2; AR; NOC2L; PRDM14; HOXA3; KLF1; TTF2; ZEB1; CUX2; WHSC1; NFE2; PBX3; FOXE1; EN1; SIX3; MYCL; MKL2; ZNF141; THAP10; CEBPA; ZNF239; CEBPD; FOXN3; JUP; PRPF6; PEX14; PBX1; DDX17; CERS4; ZNF331; ZNF257; SIM1; XRCC6; BNC1; ZFP36L2; CSDE1; PLAG1; SOX3; PCGF2; LMCD1; BACH2; TCF7L2; GTF2A2; ZBED2; PIR; SOX11; TBX3; MECOM; KLF11; ZBTB16; ATN1; LIN28A; HTATIP2; BCL11A; TCF7L1; ZNF623; ERBB4; TFAP2C; PSMC3; MEIS1; IRF6; GATA6; HMGA1; HDGF; OSR2; SOX17; FOXO1; NANOG; ZNF217; ABL1; NKX2-1; CALR; IRF4; ATF3; NFE2L2; PHIP; TFAP2A; TCF21; CTBP2; ZSCAN31; HOXB2; ID4; TCEA2
Down-regulation	145	NFKBIA; ZNF146; EZH2; ENY2; CRK; COPS2; ZIC1; XBP1; GTF2IRD1; HEY1; MTDH; ZBTB38; CCNA2; DNAJC2; KLF5; MYCBP; VGLL4; ZNF528; ZNF576; UBE3A; PBRM1; NFYB; REPIN1; KDM5D; BAZ1B; ZNF282; CNBP; ZNF148; GLI2; TRIM22; CCDC59; PRRX1; ZNF783; CAPN15; MTF2; TRIP6; RBBP7; NCOA4; ING1; SND1; ZNF3; MNAT1; ZNF134; NRBF2; CBX5; CCNC; TAF7; NFIB; TFAM; ZNF212; ZNF551; KLF2; USF2; BBX; TMF1; NFKB1; PTTG1; TSC22D4; ETS2; HLF; PAX5; FOXO4; TFDP2; NPM1; MED21; ATF1; ITGB3BP; ZNF12; GTF2I; MAGED1; WWC1; ARID4A; NKX3-1; SP110; ZNF654; ZNF552; NFYC; PHF8; NCOR2; RBM14; ZNF264; NR1I2; TFCP2L1; ZNF329; LEF1; STAT5A; EDF1; MLXIPL; TRIM28; TAF10; IRF1; PQBP1; ZBTB18; ZNF586; SAFB2; ZNF419; EHF; CHD8; NFAT5; WWTR1; NEDD8; BIRC2; NR1D2; POU4F1; EGR3; IL16; C1QBP; TGFB1; NR1H2; BRPF1; ZNF587; CARHSP1; FLNA; HLTF; KAT6B; ID2; JARID2; BRD8; SIX1; SMAD7; PFDN5; CTR9; AES; SMARCA4; BHLHE41; BCL3; ATF4; SOX9; ZEB2; MAFB; TADA3; PITX1; USP22; UBP1; BMI1; ZNF468; MSX1; MED1; ID3; IKBKAP; MED24; CREB3L1; ZNF91; EGR1; TXNIP