Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59585	Palbociclib	GSE92742	PHH	Human	24h	10uM	EID0335

Response Information :

Types	Number	Response transcription factors
Up-regulation	154	MYBL2; HMGB2; MYBL1; CBX7; KLF13; IRF6; MYRF; TFAP2C; TAF5L; HDAC9; RUVBL1; ESR1; OVOL2; KDM5D; PRDM2; TBX3; GRHL2; FOXN3; FOXE1; VGLL1; FOXM1; UBE2L3; VPS72; JUN; IRF9; CDC5L; SSBP3; SIAH2; BNC1; TRIP11; ZNF34; EZH1; TGS1; ITGB3BP; FOXC1; NR5A2; ACTL6B; HMGXB4; BATF3; SPDEF; PHF1; PCGF2; MYB; MYT1; CSDC2; ZNF394; BARX1; GATA6; SIN3B; OSR2; IFI16; SERTAD2; FOXK2; KLF9; ZNF7; NR3C1; SMAD3; ARID1A; CBFA2T2; CTBP2; THAP10; HOXD3; HIPK2; FUBP1; SSX1; EN1; RERE; THRA; SOX13; ZNF239; LITAF; CNOT3; YEATS2; CREBL2; TTF2; TLE2; ERBB4; ZNF175; CITED1; FOXF2; KLF4; HABP4; CBX4; ESRRG; FOXF1; TWIST1; INSR; WDR77; DLX2; ATF3; AR; CAMTA2; ATN1; HOXB6; POLR3C; RXRA; MTA1; ZNF623; RAD21; E2F2; CALCOCO1; ZFP36L2; NR3C2; ZSCAN18; NAB2; BCL11A; SIX3; MEN1; HOXB13; PROX1; SIM2; MYCL; RBBP8; NFE2L3; BLM; RBL2; ZNF331; MNDA; CCNH; HOXD1; RFX5; TAL1; ARID5B; TP63; ABL1; CREB3L2; TRPS1; TAF5; OLIG2; KAT2B; ZBED2; PBX3; NR1H3; SOX10; ZNF589; SOX9; MXI1; LMCD1; POU2AF1; ZNF586; ZHX2; CALR; SNAI2; ZNF217; PBX1; BHLHE41; CREB3L1; NR2F1; ST18; HOXB2; ZFPM2; TCEA2; TXNIP; WT1
Down-regulation	164	TLE1; SCAND1; MAGED1; FLNA; DDX5; GTF2IRD1; RLF; ZNF160; GABPA; UBE3A; FOXO4; TOX3; ALX1; NR1I2; NRBF2; C1D; FOXJ1; BCOR; CCNC; TCEB2; CNOT2; BAZ1A; KMT2B; NCOA4; HSF2; HSBP1; MYCBP; EDF1; CRK; EZH2; REPIN1; EYA1; ZNF205; PITX2; CRY1; TCF15; ZNF529; MSL3; HDAC6; HLF; CARM1; ZMYM2; ZNF219; VGLL4; MDM2; ZNF358; ZBTB38; NFKBIA; PLAGL1; CCNA2; MAF; CARHSP1; ARID4A; SMARCE1; MED23; POU3F1; KLF10; POU5F1B; ADNP; HDAC7; TMF1; CREG1; NFKB1; PQBP1; APEX1; ZIC1; MSX1; ETS2; MLXIPL; ZNF423; ZNF292; MED4; ZNF721; STAT5A; NR1H4; XBP1; BASP1; ID1; DNMT3B; LIN28A; ERBB2; CEBPA; HOXA7; ERG; KLF11; TRIP6; HMGN3; ASH2L; REST; HMG20A; FHL2; NR1H2; NFAT5; ZNF3; USF2; RBBP4; FOXG1; ENO1; E2F3; PSPC1; PHF8; PA2G4; ZNF131; HES1; ZNF468; ZNF652; TSC22D2; GTF2I; ZNF574; WWTR1; TCERG1; BCL3; FOS; DRAP1; NKX3-1; ZNF426; FOXD1; ID2; JARID2; MEOX2; SIX1; RAN; CUX1; IRF8; YBX1; RUVBL2; RNF111; HOXA5; RBM14; NEDD8; ZFP36L1; TLE4; TRIM29; MAFB; MTF2; ZNF44; HTATIP2; SATB1; ZBTB20; BAZ1B; ZNF432; NCOR2; SATB2; ZNF32; MED6; SRCAP; ELF5; RUNX3; ZNF226; ELK1; ZEB2; TSC22D1; EGR3; HOXB7; TCF4; PEG3; NFATC3; MED1; SOX11; CITED2; CREB1; ZNF512B; SMAD7; EGR1