Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59574	Vemurafenib	GSE92742	PHH	Human	24h	10uM	EID0335

Response Information :

Types	Number	Response transcription factors
Up-regulation	106	RFX7; SERTAD2; BATF3; TRRAP; GTF3A; PHF1; TLX1; ZNF124; SETD3; SMAD3; CDK8; TEAD1; GRHL2; MDM4; RERE; MAGED1; MTA1; YAP1; RSF1; RBBP5; SIAH2; TAF11; FOXN3; JUND; MYCL; DBP; BASP1; HTATIP2; TRIM16; E2F2; NFIX; ZNF184; GTF2I; ZNF593; HIPK3; TSC22D3; KAT5; NR3C1; SMAD5; MYRF; ZMYM2; FOSL1; HDGF; MXD1; NFYC; PAX9; ESRRG; MAZ; IRF6; ARID1A; GATA6; BAZ2B; ZFP36L2; KDM5D; KLF9; OSR2; GTF2A2; NLK; IRF3; BRD3; LITAF; TGIF1; CD3D; TGFB1I1; ABL1; MEIS1; HMGB2; DPF2; STAT4; MEN1; TAL1; MKL2; RUNX3; JUP; HMG20B; NFATC1; ZNF226; PBX3; MYB; INSR; FOXD1; BIRC2; BCL11A; TWIST1; SPEN; HDAC4; SIX2; CEBPD; SAP30; DRAP1; TRIP6; CREB3L1; ELK1; ZMIZ2; SATB1; TCEA2; ARID5B; ZSCAN31; POU2AF1; TXNIP; NR2F1; NFE2L2; WT1; LMCD1; TCF4; MED24
Down-regulation	115	ASCL1; RNF14; SCAND1; SALL2; CCNA2; EZH2; HEY1; ENY2; ZBTB38; E2F5; PRRX1; CNOT2; TAF7; CBX5; ZNF528; PITX2; ZNF835; MSX1; ZNF267; TOX; FOXJ1; ID1; GLI2; GABPB1; NEUROD1; TCEA1; ARID3A; MTF2; TERF1; ZNF148; CNBP; CAPN15; ZNF219; NRF1; ISL1; PEX2; RUVBL1; ZNF654; TULP3; HLTF; LZTS1; EYA1; REPIN1; DACH1; NANOG; COPS5; HLF; RNF111; DLX5; SFPQ; NRIP1; PURA; EYA2; ZNF146; INSM1; ASH2L; NR3C2; ID3; IRF1; SNAI2; CREBL2; PTTG1; PSIP1; RBM39; ZNF573; IL16; NR1I2; HOXA1; ADNP; MYCBP; PLAGL2; BTG1; FOXO1; POU4F1; ELK3; TP63; HIC2; NFIL3; SMARCA2; PFDN5; BNC2; PHOX2B; PSMC3; ING3; RNF4; ZNF432; UBP1; ZNF131; ZNF266; WWTR1; EGR2; NR4A1; MECOM; MYT1L; MYBL1; RFX5; EGR3; CHD7; LOXL2; SSBP2; FOXG1; ID2; ZBTB20; USP22; ZNF589; ZNF232; FOSB; CREB1; HOXB6; ZEB2; PEG3; ZNF586; MAFB; ZMIZ1; EGR1