Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59550	Safinamide	GSE92742	NPC	Human	24h	10uM	EID0334

Response Information :

Types	Number	Response transcription factors
Up-regulation	94	SP3; GATA2; ZNF552; GFI1; MEN1; NKX3-2; IFNB1; ZSCAN32; PLAGL2; CBX6; E2F6; ZNF211; BRPF1; ZNF408; RBBP8; BLM; LYL1; TAF5; SOX21; HHEX; NR2F2; MAF; CHAF1B; TADA3; PRDM4; RBM14; HOXA11; KLF1; WNT4; MEF2A; CNOT2; TBL1X; ZBTB40; ZNF443; HEY2; VGLL1; KAT2B; NFATC1; ELF1; RNF10; AR; CBFA2T3; IL16; LEF1; NELFB; HMGA2; RBBP7; CERS4; RFC1; ATF5; SIX1; SOX17; RFX5; PGR; PAX5; BIRC2; TFDP1; UBP1; CUX1; TAL1; RUNX3; CDK7; MAFG; MECOM; ZBTB16; FOXF1; HTATIP2; PIR; IKBKAP; WT1; ZNF516; ZEB2; NFE2L3; ZFP36L1; MTF2; MNAT1; FOXO1; DLX5; WWC1; ESR1; DNAJC1; SERTAD2; EGR2; MSX1; MYCN; CDK2; MTA1; HOXC6; HOXB6; INSR; BHLHE41; SOX9; CRK; KAT6A
Down-regulation	94	GTF2A2; ACTL6A; ZNF226; HOXC4; PITX2; ZNF354A; SNAI2; HOXD1; ZNF562; NANOG; TFAP2C; NRIP1; ZNF512B; ZNF536; HOXA1; ZHX3; TCF7; TDP2; HIVEP2; LOXL2; PRKDC; ZNF22; KLF2; TTF2; PLAG1; ZNF432; ARRB1; MAFF; ZBTB38; TRIM29; PHOX2B; FOSL2; HDAC7; ARID4A; SKI; SPEN; AHR; KLF7; JUN; HLF; TERF1; NHLH2; TOB1; SATB2; NR1D2; SMAD6; BAZ1A; TWIST1; MYCL; STAT4; CREB1; KLF9; MAGED1; SOX10; MYBL1; ZNF117; RBL2; JUNB; NR4A1; TULP3; NCOA3; CEBPB; NR3C2; ZNF652; TP63; MYB; MED13; CRYM; EYA1; PEX2; ZNF423; ZNF331; PLAGL1; PBX3; INSM1; GMNN; RAD21; ATF3; BASP1; TOX; YBX3; ID4; TCF4; GATA6; USP22; ZSCAN18; ERBB4; HOXA5; TCEA2; SMAD3; NUP62; PBX1; FOXG1; FOXO4