Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59542	Jnj-26481585	GSE92742	NPC	Human	24h	10uM	EID0334

Response Information :

Types	Number	Response transcription factors
Up-regulation	124	E2F2; HMG20B; STAT3; ZNF552; NKX3-2; PITX1; CBX2; ZNF282; ZNF580; BTF3; SNAPC4; CBX4; TSC22D1; HOXC4; SOX4; JUND; FOXO3; ZNF226; ZNF816; SSBP3; CIZ1; ZMYND8; RUNX1; RHOA; GTF3A; ZNF79; FOXA2; MLX; RBPMS; SMARCB1; ZSCAN32; KLF15; ZNF444; ZNF652; AATF; ABL1; LHX3; ATN1; NCOR2; ZNF384; MZF1; SIX6; NEDD8; KMT2A; PAX6; CAPN15; SOX9; ERG; RING1; SHOX2; BCL3; ZNF211; IRF3; SPDEF; SUPT6H; PAX9; NFE2; ELF3; HOXD3; ARID1A; SIN3B; MED24; MITF; TCEB2; AIP; DMTF1; THAP11; ST18; MED13; MLXIP; ZNF83; CBX6; DEAF1; ZNF177; MNX1; ZNF175; NKX3-1; BATF; PAXBP1; FOXD1; PMF1; SUPT4H1; IRF4; ZFHX4; LMCD1; HOXC6; SP140; PCGF2; SND1; DDX17; PHIP; EGR1; TCEA2; TEAD1; CNOT3; CALR; LOXL2; KAT2B; SAFB2; ZFHX3; HMBOX1; IL16; BCL6; CDK7; MTA1; TRIM24; TAF1D; NR2F2; HLTF; ZBTB16; ZBTB18; FOXA1; MSX1; HIPK1; KDM5D; PPARD; CD3D; HHEX; ERBB4; ZNF91; TSC22D2; KAT6A; BTG1; DRAP1
Down-regulation	157	SFPQ; TRIM29; THAP4; MYBL1; TBPL1; KLF6; BBX; ERF; ZBTB38; HMGA2; SMARCA5; NFYB; SMAD4; HDAC4; HMG20A; C1D; SUMO1; ID1; HMGB1; SPEN; RBBP8; ZNF281; ZBED1; SKI; SP100; RBBP5; TAF11; ZNF184; NFIB; DACH1; RNF138; CENPF; ARID5A; MTDH; ZBED2; CBFB; MED6; PAX5; ID3; SNAI2; PHF20; USP22; KLF5; GABPB1; BCL10; POU4F1; ZFP36L2; EHF; SMAD1; RNF111; TFDP2; TGIF2; MBD2; MLLT10; PSIP1; TDP2; ZNF165; ZMYM2; PIR; RNF6; MYCL; PTTG1; CREM; TFAM; SMAD7; TRIP4; PBX3; E2F5; COPS5; EED; CDK8; CREB3; RCOR1; BCL11B; ING2; UBE3A; LDB1; KLF13; MEOX1; TERF1; MNDA; ID4; NRBF2; MAML1; PPARGC1A; KLF10; TOPORS; BCOR; HNRNPD; CNBP; TBX3; RORA; SP110; RNF14; KLF7; BCL11A; NR1D2; ZNF529; ACTL6A; UBE2B; RB1; ARL2BP; NR1I2; TLE4; MEIS1; EYA1; DLX2; RFX5; HOXB2; MTF2; HIF1A; KLF3; EGR3; HIC2; HMGA1; SERTAD2; EGR4; BHLHE41; TCF7; ETS1; WT1; CNOT6; TFAP2C; E2F3; NR3C2; GMNN; ARNTL2; CRY1; ZBTB1; ZSCAN18; ZEB2; KAT6B; VDR; PEX2; ELK3; IFI16; ZFPM2; FOSB; MXI1; ISL1; ASCL1; CRK; MNAT1; TRIM22; NUP62; BASP1; SMAD3; ATF1; NR2F1; ETS2; ETV1; FLNA; BMI1; EGR2; FOXG1; NFKBIB; FOXO4