Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59534	Canertinib	GSE92742	NPC	Human	24h	10uM	EID0334

Response Information :

Types	Number	Response transcription factors
Up-regulation	138	ADRB2; FOXA2; TP53; CBX2; MAP3K10; IFNB1; RELA; TADA3; KLF11; KLF15; PDLIM1; OVOL2; ARID5B; RBBP8; TCFL5; SETD3; PLAGL2; CREG1; SIRT2; CDYL; PRDM14; HES1; SUPT5H; FOXF2; CXXC1; LHX3; TEAD4; GFI1; FOXK2; DDX5; CDX1; ZNF580; HDGF; TSHZ2; RBM14; ACTL6B; TFE3; CNBP; WT1; TAF11; GTF3A; TCF21; DEK; TFDP2; BARX1; SPIB; RING1; E2F5; TAF9B; TDP2; CCNH; TRIB3; CBX3; VGLL1; CTCF; CSDE1; SSBP3; KAT2B; ZNF232; URI1; ZIC1; RNF6; ILF2; KDM4C; ETV4; RFC1; ZNF211; VDR; NCOA2; SOX13; NKX2-1; HDAC9; CTBP1; VPS72; ZNF512B; RBM39; ARID3B; TFEC; CEBPD; DMTF1; VEZF1; ZFP36L2; CEBPG; ATF3; ZNF589; WDR77; SF1; NFE2L3; SHOX2; RORA; UBP1; RUNX1; KLF3; BCL11B; CBX4; KDM5D; SETDB1; JUND; TTF2; FOXN3; JUP; ATF4; HIPK1; IRF4; COPS2; TRIM24; AEBP1; MED6; SERTAD2; TGFB1; TFAP2A; ATF5; RUNX3; RAD21; SLC2A4RG; THAP11; ZNF217; ID1; FOXA1; PBX3; CERS6; HMGB2; DLX2; CD3D; HMGB3; MEIS1; PIR; TOX3; SMAD1; NFATC4; LMCD1; KLF10; NFKBIB; NKX2-2; BNC2; TCEA2; CITED2; CRK
Down-regulation	124	PURA; KMT2A; ZNF562; HOXC4; TCF4; MITF; CITED1; BCL10; TCF7; ZNF226; ATF7IP; KAT7; ZNF593; ING3; ZBTB48; TGFB1I1; RCOR3; MXD4; THAP1; HOXC6; RNF141; TSC22D2; MED23; ZNF652; ZNF292; KAT6B; ZNF3; ZHX3; TFEB; FOXO3; EP300; OLIG2; CHD9; TCF25; TAF1D; MAFF; ZNF264; CREB5; DEAF1; CHD4; SMARCA1; RBPMS; BBX; TCEB2; TRIP6; BAZ2B; KLF7; HSBP1; NPAT; EYA2; RNF111; SKI; FOSL2; POU4F1; MTF2; MED13; PRKDC; AES; NRIP1; HMBOX1; BAZ1A; TRIM29; ZNF148; SFPQ; ZNF551; ZBTB20; HMGXB4; EGR3; SREBF1; HTATIP2; NFX1; ZNF107; ELK3; NR2F1; ZNF587; PATZ1; ZEB1; KLF2; TFCP2; JAK2; HEY1; NFAT5; HIC2; SCAND1; ZBTB18; NANOG; CHD8; EYA1; DLX5; TBX3; ITGB3BP; ERBB2; HIF1A; KAT6A; ZNF22; ARNTL2; SIM2; KLF6; LZTS1; NKX3-1; SNAI2; MAFB; SIAH2; PAX5; BIRC2; SALL1; MAGED1; MSX1; LOXL2; CAMTA1; NR2F2; MED1; AHR; TRIM22; IRF8; TBL1X; PCGF2; CTBP2; PLAGL1; TLE4; SMAD3; PBX1; FOXO4; CEBPA