Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59533	Bosutinib	GSE92742	NPC	Human	24h	10uM	EID0334

Response Information :

Types	Number	Response transcription factors
Up-regulation	91	NFKB2; FOXI1; ZNF264; TGIF2; TCF7L1; ZNF124; REL; HIC2; RBFOX2; STAT2; SIX3; KLF3; CCNC; GTF2F1; ESR1; CDYL; EPAS1; ZNF721; TCF7; CTNNB1; NR0B1; LIMD1; ZNF611; TRPS1; RUNX1; ZNF444; HEY2; LHX3; KLF1; ZNF224; HOXA3; TAF4B; TAF1A; WNT4; MYRF; ZNF160; TWIST1; ZNF44; ZNF232; ZNF665; FOXA2; CARHSP1; HDGF; ZNF652; PAWR; TEAD4; SOX17; BTF3; PHF20; MEIS2; SMAD3; FUBP1; TFCP2L1; KLF6; MAFG; CALR; CREB3L1; IRF9; ETS1; KLF13; PNRC1; PSMC3; INSM1; USP21; TCF7L2; HMBOX1; HOXB2; THAP7; RBM39; FOXO1; AEBP1; DLX5; CEBPB; ELF1; NR4A2; INSR; CREM; MEIS1; CRYM; ZHX2; ZFPM2; LEF1; SMAD7; HMGB3; VPS72; WT1; BTG1; TCEA2; KAT6A; TOX3; CRK
Down-regulation	124	PITX2; ZIC1; BRD4; CCNE1; NFE2L1; HDAC6; RCOR1; TRAK1; ZBTB11; PHF8; BRPF1; CEBPG; FOXJ3; SNIP1; TRRAP; SMARCD3; ZNF12; URI1; TAF11; HCFC2; TLE2; ZBTB18; ZNF148; SSBP2; NRIP1; ACTL6A; SUPT4H1; REST; BRD3; NFIB; ZNF432; BAZ1B; TFDP2; TADA3; ZNF84; USP22; USF2; ZBED1; TSC22D4; PSIP1; WHSC1; MYCBP; TSC22D1; SETD2; MYC; REPIN1; ZNF189; NR2F1; CITED1; MED17; EED; PSMC3IP; ELK1; TAF7; AHR; MAML1; TOB1; RNF6; TAF10; CTR9; CBX3; ZFX; TAF1D; GTF2IRD1; ST18; UBP1; CREB1; PRKDC; IL16; SIX1; YBX3; BTAF1; MAF; ATF3; HLTF; EP400; SMARCA1; WWTR1; NCOA1; NCOA4; EGR2; ASCL1; CLOCK; ZNF302; SMARCE1; ETV1; TSG101; HDAC9; HOXB7; ZNF131; ERBB2; RB1; APEX1; IRF4; PAX5; MYCL; ZNF329; ID1; TCEB2; TBL1X; TRIM29; BATF; ZEB1; ZSCAN18; CTBP2; PCGF2; TP63; NPAS2; TCF4; NUP62; HOXC10; EMX2; WWC1; KLF4; PIR; CEBPZ; SMARCA4; SMARCA2; NR2F2; EGR1; STAT5B; SOX9; FOXG1; FOXO4