Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59526	Pu-h71	GSE92742	NPC	Human	24h	10uM	EID0334

Response Information :

Types	Number	Response transcription factors
Up-regulation	304	FOXF2; NR1H2; EED; ATF6; TBX21; NFKB2; CAMTA2; SNAPC4; CREB3L2; KAT2B; CEBPD; FOS; THRB; KLF9; CBX7; ADRB2; NR4A2; ZSCAN32; LHX3; RFXANK; CCNH; KLF13; KLF11; TULP1; ZNF215; PRDM1; CALCOCO1; ZNF586; ZNF394; SOX17; ZNF500; NKX2-5; MXI1; CDIP1; FOXI1; IRF9; PRDM2; TADA3; SMARCD3; SPDEF; SOX21; KLF15; GATA1; TGFB1; NHLH1; EMX1; TP73; REL; MLXIP; IRF3; MITF; MED17; ECD; ZNF665; PCGF1; POLR3C; BNC1; ZNF573; ATOH1; ZNF335; HSF4; VDR; NEUROD2; EPAS1; NEUROD6; MAP3K10; RNF6; NRL; ZNF235; MYBL2; MEN1; ARID5B; NFE2L2; HDAC11; TUB; CDX1; IFI16; ARNTL; MED25; JUN; PNRC1; TBX10; ZNF75D; ZNF611; DDIT3; ACTL6B; RARG; GATA2; BCL11A; ELF4; SNAI2; TAF6L; STAT1; ZXDC; VGLL1; ESRRA; PRDM4; ZBTB16; TDRD3; BRD4; ZNF44; CRYM; MBD1; ZNF444; CAPN15; ZNF343; PRDM14; JUNB; MYBL1; CNOT3; FOXL2; ZBED2; HOXB2; MED15; RELA; ZNF85; SSBP2; TAF1C; ASH1L; EHF; ZBTB7B; NFYA; TFEB; OVOL2; TAF5L; IRF6; ZNF654; AIRE; TFAP2A; BAZ2A; KDM4C; SIX3; NFATC4; HINFP; ZNF264; FOXJ2; PBXIP1; CBFA2T3; TFCP2L1; NR5A1; HOXB13; GBX1; SOX13; MECP2; HHEX; HDAC9; ZNF263; KDM5C; PAX6; FOXA2; ZNF467; ZNF688; KLF3; CSDC2; BARX1; FOXE1; NR4A1; ARL2BP; TCF21; ZNF175; TRIP4; SIRT7; ZNF669; NR1H4; TERF2; E2F4; TRIB3; ZKSCAN3; ZNF91; ESRRG; NR5A2; VENTX; IRF1; ZBTB43; ZBTB25; ETS1; TULP3; NPAS2; ZNF350; CRTC1; BCL3; HOXB1; ZNF331; LZTR1; MXD4; SOX18; CEBPG; HSF1; TAF1; ZNF33B; USP21; CBX4; PDLIM1; RORC; FOXH1; HOXA11; FOSB; GFI1; CREB1; KLF4; PHF1; CIZ1; TDP2; CBFA2T2; ZNF580; ZNF556; ACTL6A; SP140L; HIPK1; NFIC; HOXD1; ID2; CD3D; RBL2; PHIP; SRF; ZNF557; NEUROD1; KLF1; SRCAP; SPIB; ZHX2; SP100; CEBPB; TGFB1I1; TFAP2C; GCFC2; GON4L; TTF2; TRPS1; SMARCC2; TRIM29; VPS72; TRIM22; DLX5; MDM2; DMTF1; CTBP1; HOXB5; CITED2; KLF5; ZNF589; ATF3; SETDB1; HOXA5; SHOX2; LYL1; NR3C2; PSMC3; DACH1; ZKSCAN1; TRIP6; ZNF117; HBP1; SOX10; MEIS2; AES; PPARD; CREBZF; BRD2; ZBTB38; ZEB1; STAT4; ZBTB20; NFE2; CDK2; HLX; DBP; KLF10; HTATIP2; TXNIP; WT1; CBX6; NR1D2; ZNF160; THAP7; IL16; SMARCA2; GMNN; ZNF266; HIRA; IRF4; TBX3; ZNF430; MNDA; BNC2; ERBB4; HOXC10; IRF7; OSR2; ZIC1; ID1; ESR1; LEF1; TP63; ID3; SALL1; IRF8; FOXO1; CDK7; AEBP1; RORA; BTG1; CRK
Down-regulation	273	EZH2; HDAC2; PUF60; NFIL3; RBBP4; SMARCA5; YBX1; HMGN3; CCNA2; PSIP1; DNMT3B; TBPL1; HSF2; NEDD8; SOX2; ZNF226; TCF12; SOX11; HMGA2; KAT7; RLF; E2F5; BRD8; EDF1; DDX5; ZKSCAN7; MDFI; PATZ1; SMAD2; HDAC6; GABPB1; TBL1XR1; NRIP1; RUVBL2; PRKDC; MAGED1; RAN; PSMC3IP; PBRM1; SUV39H1; PHF20; POU3F2; NONO; ZNF24; RFX7; CCNC; JARID2; ZNF334; TRIM28; PARP1; FOXJ3; MED24; TP53; ZNF236; SREBF1; PCGF2; TBP; ENO1; WDHD1; CBX5; USF2; TOX; TCF7L1; TADA2A; BIRC2; ELF2; MYCBP; BRD3; BRCA1; EYA1; RBM14; ZNF292; TFAP2B; BCLAF1; HSBP1; NRBF2; ZBTB18; E2F3; CTNNB1; CITED1; CREB5; SMARCE1; CENPF; BATF3; RCOR1; CARHSP1; GTF2A2; MED23; ZFY; PMF1; LZTS1; SNW1; PHF2; ZNF302; RNF138; PITX2; ZBTB11; TRRAP; CHD7; VGLL4; ASCL1; TCERG1; NAB1; TAF9B; POU4F1; HOXC6; HMGXB4; NUP62; MYT1; NRF1; NCOA4; PLAG1; SETD2; CBFB; E2F6; UBE2I; RHOA; HMG20A; TBL1X; HNRNPD; ISL1; ATF4; THAP1; HDAC1; FUBP1; ZNF112; ZNF787; ZNF606; HMGB3; NPM1; LPIN2; MMS19; ZFP37; MEOX2; FOXO3; KMT5A; SNIP1; CHD9; ITGB3BP; PIAS2; SPEN; EWSR1; ELK3; MLLT10; PREB; ING2; L3MBTL1; TAF10; BMI1; STAT5A; ETV5; NCOR2; ERBB2; RUVBL1; TRIM16; ZNF587; ZNF528; GABPA; SUB1; PQBP1; RBFOX2; XRCC6; ZNF410; BAZ2B; CHD1; PBX1; MED4; FOXG1; ZFHX4; CNOT1; TAF1D; IRF2; SMAD4; THRAP3; KDM2A; EMX2; NR2F1; SSRP1; BAZ1A; BRF2; TCF4; TRAK1; FOXN2; SUZ12; ZNF423; TEAD1; TOPORS; SMARCA4; TSC22D2; SIX2; ASH2L; TSC22D1; ETV1; APEX1; HEY2; CTR9; ELK1; RBL1; MED1; ZNF22; OLIG2; HOXB7; ZNF711; WWTR1; ZNF529; SIX1; MAX; DNAJC1; NFIB; RB1; TFAM; SOX9; KDM5D; INSM1; TLE4; SALL2; ZBTB1; FOXD1; CREM; ZBED4; UBE2B; NLK; PRPF6; ZMIZ2; CERS4; TCEA2; FLNA; ZNF532; SMARCA1; SMARCC1; BTAF1; BAZ1B; RBPJ; NR2E1; SCAND1; ARRB1; TFEC; CRY1; HDAC7; CEBPZ; NANOG; CBX3; SUPT4H1; ZNF646; CAMTA1; PLAGL1; ZEB2; PTTG1; PAX5; TWIST1; CUX2; USP22; CERS6; MECOM; IKBKAP; MSX1; MYCN; MYB; HLTF; PIR; AHR; DRAP1; THAP11; NR2F2; ETS2; BASP1; KLF2; STAT5B; NKX3-1; INSR; PEG3; ID4; FOXO4