Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59516	Epoxycholesterol	GSE92742	NPC	Human	24h	10uM	EID0334

Response Information :

Types	Number	Response transcription factors
Up-regulation	200	NFKB2; SMARCD2; SUV39H1; BHLHE40; MEF2C; DAXX; NR3C1; SPDEF; MDM2; MXD4; TSC22D3; HOXC11; PML; PRDM1; STAT3; NR0B1; FOXE1; ERF; RCOR1; UBP1; EGR3; HHEX; RBPMS; CASZ1; KDM5A; NR4A2; HOXC10; DMTF1; ZNF512B; TEAD4; AES; TXNIP; NR3C2; SIAH2; THAP11; BACH1; MAFK; THAP1; TRIM28; ZNF335; TRIM32; FEV; TRIP6; HOXA3; PRMT2; BCL6; NOC2L; HOXC6; KAT7; SMAD5; SOX5; EDF1; HDAC3; TGFB1; IRX5; RARG; GTF2I; POU6F1; ATF7IP; CBX4; PPARD; TLX1; ELK3; MXD1; GLI1; HMGA1; NELFB; TRIM16; KLF4; ZBTB39; RNF141; SMARCD3; NFIB; SMARCD1; HOXC13; SLC2A4RG; PITX2; DNAJC2; ING1; ZNF556; THAP10; GATA2; JUNB; DEAF1; MED21; PRDM2; TSC22D1; BCL3; SFPQ; NR4A1; FOXC1; CIC; ELF2; ALX1; NAB2; KLF2; ZBTB20; NEUROD6; HIVEP1; ZSCAN31; CREG1; KDM5D; HLF; SOX18; TP63; CUX2; SNIP1; CBFA2T3; DR1; CBX7; ZNF189; SIM2; ARID4A; TFAP2C; ZNF711; HDAC4; MYT1L; ELF1; CHD1; REL; ZBTB38; EPAS1; TFCP2; NFKB1; MYBL1; MNDA; SSBP3; ARNTL; ZNF652; FOXF1; NR1H4; MNAT1; KDM4C; DLX4; FOXF2; BCL10; ZNF557; ZNF146; CITED2; ELK1; SP140L; EHMT2; CTBP1; NR1D2; SMARCA1; TBL1X; CREB3L1; TAF6; HNRNPD; YBX3; TSC22D4; RB1; JAK2; NR4A3; RORA; SHOX2; SOX9; ARNTL2; PLAGL1; ZNF394; SIX1; BCL11B; NR2F2; NFATC3; C1QBP; ZNF117; RFX5; DNAJC1; MTA1; SSX1; ITGB3BP; ZNF160; RBL2; ZBED2; CRYM; CTR9; NKX3-1; CREM; IRF6; FOSL2; HLX; HMGB2; WWTR1; ELF3; DLX2; MEIS2; ZKSCAN1; ZBTB16; CEBPZ; AHR; ENO1; POU2AF1; ETS2; SMARCA2; CRK; CTBP2; KLF10; MAFB; DRAP1; KAT6A
Down-regulation	279	SALL2; KLF7; ZNF24; PCBD1; KAT2A; AATF; JUND; ZNF83; MEOX1; ZNF232; SSBP2; PUF60; HEY2; HIPK2; FOXO1; MYNN; ZNF410; PURA; ZNF432; PPRC1; ATF3; TFEB; ZNF93; SIX3; TBX2; MECOM; UBE3A; HDAC6; LEF1; SIX2; PAX5; BRD8; FOXO3; EYA2; RSF1; PRKDC; MXI1; TSG101; COPS5; ASCL1; CHD7; ZNF195; MED1; ZNF415; ZNF140; CNBP; TCF12; MLX; GMEB2; VGLL4; KAT6B; MEIS1; XRCC6; FOXA2; PATZ1; TBP; IRF2; CALR; ZNF143; SAP18; NFE2L1; E2F8; DDX5; MED27; ZFHX3; E2F5; TCF7L1; AIP; RYBP; SOX4; PMF1; NCOR2; ZNF141; TBL1XR1; APEX1; MED20; RFXANK; ZNF544; ZBTB18; MMS19; DDIT3; NONO; ZNF354A; SOX17; TP53; ZMIZ1; CCNE1; RNF138; MED24; ZNF573; ZNF606; INSM1; ATF2; SOX13; MAFF; HDAC5; EMX2; BRD4; SMAD2; GABPB1; DNMT1; ORC2; ADNP2; PDLIM1; ERBB2; PREB; VGLL1; CBFB; TCEB2; SREBF1; ZNF177; E2F3; EED; STAT1; VPS72; HDGF; ACTL6A; KAT8; ZFP36L2; ID3; PHF8; EP400; CENPF; ID4; TFEC; NCOA2; PBX3; NRF1; CIR1; SMARCE1; PHF2; TAF5; HOXD11; ZBTB3; TAF9B; ILF2; FUBP1; SRCAP; MED14; SUPT3H; ATF4; BACH2; HOXB6; BTAF1; NFE2; HIVEP2; FOXJ3; GTF3A; TFDP2; SMAD7; PEX2; TCFL5; GATAD2A; NFE2L2; PHOX2B; ARID3B; L3MBTL1; HMBOX1; ZNF10; ZNF131; ZNF423; MYCL; SNW1; MED23; SIX6; RAD21; ZNF22; TDP2; SPI1; SMARCC2; TTF2; UBE2L3; POU3F2; WT1; TCEA1; ZNF32; POLR3C; CERS6; PLAG1; MED13; PPP1R13L; MYCBP; BLM; BCOR; HOXB7; CDK8; CEBPD; NFKBIA; CXXC1; NCOA4; CSDE1; PKNOX2; ID1; BRD7; SETDB1; HEY1; PMS1; HIF1A; MSX1; CHD8; GTF2IRD1; ZNF468; HDAC9; SPEN; ID2; TRAK1; CHD4; TFCP2L1; ZIC1; KLF9; HOXB2; DDX17; CCNC; TAL1; CCDC59; PEX14; ZNF266; PSMC3; ZNF91; NCOA3; TULP3; ARRB1; ZNF529; CREB1; TAF10; SOX11; IKBKAP; LDB1; ZNF331; ZFPM2; SP100; ST18; KLF6; ZNF43; HIRA; ZNF516; ETS1; SMARCB1; ZNF665; NUP62; HOXB5; RBPJ; TOX3; ISL1; HOXD1; TRIM24; INSR; AEBP1; EYA1; PCGF2; ZFP36L1; ZNF532; ZNF165; TBX3; BTG1; TCF21; ZSCAN18; FOXA1; HMGB3; SMAD1; ZNF274; TLE4; NFATC4; GMNN; HMGB1; IRF8; SCAND1; SMAD3; TCERG1; FOXG1; STAT5B; DACH1; PBX1; BRD2; TSC22D2; SNAI2; NFKBIB; PEG3; FOXO4