Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59475	7,8-dihydro-l-biopterin	GSE92742	NPC	Human	24h	10uM	EID0334

Response Information :

Types	Number	Response transcription factors
Up-regulation	55	KDM5A; SMARCA1; RBBP8; NFATC4; ALX1; NR4A3; NEUROD6; SOX10; PURA; EGR3; PITX1; ZNF331; MLX; NR3C1; ELF3; ZZZ3; FOXF1; GLI3; NFX1; GRHL2; CD3D; WDR77; SP3; HOXC10; IL16; EHF; HSBP1; EYA1; CREB3L2; RBPJ; ETS1; NR4A1; DMTF1; TBL1X; IRF6; ZBTB16; TWIST1; BCL11A; IFI16; ETS2; TBX3; HMGB1; ESR1; MEOX2; NFIB; POU2AF1; LMCD1; ASCL1; IKBKAP; IRF8; CTBP2; SMAD7; CRK; MSX1; KAT6A
Down-regulation	66	HMGN3; NFE2; DDX5; RUNX1; REST; TAF9B; ERG; SSBP2; ZIC1; ZHX3; E2F5; CITED2; EPAS1; KLF11; NLK; ARL2BP; ZNF623; LOXL2; USP22; MYT1L; LPIN2; ZBTB38; HDAC7; NCOA1; HIVEP2; MEIS1; RBBP4; PRKDC; PPARGC1A; TAF7; ZNF768; NONO; TRIM16; MAGED1; BPTF; NR2F1; ZNF652; HHEX; SERTAD2; TFEC; AHR; ZNF302; IRF1; TOB1; PBX3; DACH1; TGFB1; JUNB; FOXC1; PIR; TSC22D2; KLF2; MNAT1; THAP11; KLF9; TCEA2; ENO1; ERBB4; WT1; SMAD3; SALL1; SOX9; CDK7; NFKBIB; NUP62; FOXO4