Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59469	Withaferin-a	GSE92742	NPC	Human	24h	10uM	EID0334

Response Information :

Types	Number	Response transcription factors
Up-regulation	137	ADRB2; PRDM2; ARID5B; CAMTA2; GATA2; TCF7L1; CCNH; SOX13; ZNF675; POU2AF1; NR3C1; HOXC4; DDIT3; ZNF335; LEF1; PRDM14; CUX1; HOXA2; TBX10; ESR1; PPARD; LHX3; TAF4B; VDR; AR; HOXA11; HOXA4; SOX5; ZNF544; KLF7; WT1; TEAD3; TWIST1; ZNF257; TCF7L2; HESX1; ZNF117; TCF3; HOXA3; NFIX; MAFG; TP53; ZNF85; TFDP2; SPDEF; ZNF573; TRPS1; ZNF253; MED12; ZNF589; IRF9; TGFB1I1; OSR2; ZNF91; RING1; ZHX2; ZNF165; ZNF141; ZMYND8; RFC1; ZIC1; HEY2; IRF6; REL; YAP1; EN1; TP63; RBM39; ZNF93; FOXD1; DLX2; ZNF273; ZNF394; NR0B1; KLF11; PIAS2; GLI3; NR5A2; TRIB3; IFI16; PRRX1; PAWR; ZNF232; ZNF43; CBX6; MED15; KDM4C; ZNF415; PFDN5; C1QBP; MEIS2; HOXC10; ZNF665; SPIB; AEBP1; MYBL1; PLAGL1; ZNF423; GTF3A; PEG3; PCGF1; ZFHX3; ZNF611; TOX; DLX5; DMTF1; SMARCB1; HDAC9; TULP4; BHLHE41; SOX17; TDP2; MAF; PAX5; TFAP2C; BCL11A; ZFP36L1; MAFB; SNAI2; ATF3; KLF9; RUNX3; INSR; TCEA1; YBX3; VPS72; EMX2; ZKSCAN1; MBD2; BNC2; RORA; TCEA2; HOXA5; MYB; PBX3; KAT6A; CRK
Down-regulation	151	PCBD1; KDM5B; CHD1; ZBTB38; BRCA1; NFYB; CENPB; ATF7IP; TFAM; VEZF1; PPARGC1A; CHD3; BRD8; PKNOX1; MED7; NFAT5; MLX; UBP1; ZNF672; ING3; GABPB1; MAGED1; AFF1; ZNF148; RBPMS; ZBTB48; SSBP2; TCF12; SFPQ; MTF2; TAF10; ARL2BP; BAZ1B; RBM14; REPIN1; ELF2; TRIM28; NRIP1; ZBTB11; CARHSP1; BCLAF1; SMAD4; ZNF267; HDAC3; TERF2; UBE2B; HMG20A; BASP1; USF2; BCL10; RNF111; TMF1; IRF3; ADNP2; CREB1; SSRP1; ARID4A; SNW1; TSC22D4; ZBTB18; KMT2A; ZNF12; PSIP1; GTF2IRD1; ELK3; BRD3; SMARCE1; HIVEP1; PIAS3; MED13; ZBTB1; ZNF576; RCOR1; MITF; TOPORS; ARRB1; EGR3; CTR9; DPF2; MYCBP; FHL2; RSF1; ID2; PITX1; BLM; DEK; ACTL6A; USP22; ELK1; EED; ZMIZ2; SMAD2; ID1; MYCL; SMAD6; SUPT4H1; ASCL1; CRY1; NFKB1; ETS2; ETV1; NCOA4; HLTF; ZNF131; NFIB; TCF4; POLR2A; TRIP6; NR1H3; ZNF22; CLOCK; MED1; CRYM; ID3; NR1D2; TLE4; SIX2; SREBF1; ZNF146; KDM5D; ZNF217; CBX3; WWC1; FLNA; TBL1X; SIAH2; CDK7; TAF1D; NUP62; BATF3; MED6; ENO1; FOSL2; ETV5; AHR; ERBB2; BCL3; PIR; LOXL2; TRIM22; ATF1; BMI1; SMAD1; PCGF2; TOB1; EGR1; SMAD3; EGR2; FOXO4; SOX9; CEBPA