Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59455	Torin-1	GSE92742	NPC	Human	24h	10uM	EID0334

Response Information :

Types	Number	Response transcription factors
Up-regulation	205	CBX7; JUP; ZNF444; RBBP8; ABL1; RBFOX2; SIRT2; HBP1; CALCOCO1; CAMTA2; RELA; ARID5A; ZNF816; SIN3B; HSF1; ZNF544; ZNF500; RELB; KMT2A; TAF6; MEN1; HOXC13; FOXO3; ZNF446; RBPMS; ZNF512B; NR2F6; ZHX2; SPDEF; TRIM29; DMTF1; ZNF665; PAWR; PRDM2; DLX2; ZNF44; ZNF419; ZNF264; KDM5C; ETS1; TGFB1I1; OVOL2; PHF1; HMGXB3; HSF4; PHF20; CBX4; LHX3; ZNF274; HOXC11; ZNF202; ZNF384; TFE3; ZFPM2; BARX1; MLXIP; ZNF215; ZNF580; IRF2; TRIP6; HOXB13; NR1H2; ZNF76; DEAF1; TCF7; CRTC1; TRPS1; IRF1; NFRKB; KAT2A; UBE2B; ZNF394; HOXD1; TBX3; SATB1; NFATC3; NCOR2; GON4L; GBX1; GTF2IRD1; MNT; GLI3; TFAP2C; CNOT3; MED15; ZNF611; IRF6; ARNTL; CREM; PRDM1; MZF1; MED17; NR1H3; REPIN1; NR3C1; HOXD11; TGFB1; PRDM14; TFAP2A; ZNF12; BHLHE41; CNOT2; GFI1; HIPK2; JUN; ZZZ3; HDAC5; SOX9; BPTF; CTBP1; CSDC2; POU2AF1; MITF; RFX5; NUP62; RARG; MNX1; HMBOX1; ZNF589; VGLL4; SNAI2; FOXF2; FOXK2; TRIM32; PPP1R13L; ZNF117; KLF13; CDK9; FHL2; HDAC1; ZNF304; ZNF331; LDB1; ZNF195; TCF20; SIM2; SALL2; MYBL1; TP63; ZNF430; TSC22D4; TRIM16; SF1; KLF11; BASP1; NFKB1; PEG3; GRHL2; TCF25; ZKSCAN1; SMARCC2; MYC; PBXIP1; THAP11; CITED2; IL16; NLK; IRF5; ZSCAN31; PNRC1; TRIB3; USP22; MEIS2; CREB3L2; TGIF1; SUPT6H; AEBP1; HDAC7; ST18; ZNF652; CEBPB; PTRF; ZBED2; PRRX1; INSR; CD3D; MAF; TCEA2; BAZ2B; CDK7; BTG1; ETV1; TULP3; MNDA; TXNIP; BCL6; ZBTB16; ZFP36L1; NR4A2; HIPK1; MYRF; ELF5; ERBB4; IRF9; OSR2; ZSCAN18; HIRA; ESR1; IFI16; FOXG1; ZNF91; CRK; WT1; HMGB2; MAFB
Down-regulation	178	EZH2; E2F8; GABPB1; RHOA; CCNA2; YEATS4; ASH2L; HMGA2; BRCA2; HDAC2; PSIP1; NFIL3; SUV39H1; BRCA1; MYBL2; PRKDC; WDHD1; NR1I3; CENPF; DNMT3B; WHSC1; DDX5; GTF2A2; DACH1; PCBD1; BAZ1A; CALR; SMAD6; POLR3F; MYNN; RLF; HSBP1; ZNF236; TLE1; SOX11; SUB1; CARHSP1; ZBTB18; NHLH2; CCNE1; SUZ12; BCLAF1; ZNF334; ZNF112; MYCBP; SPEN; ZNF292; RBBP4; NCOA4; HDAC6; NFE2; HLTF; ZSCAN16; PLAG1; UBE3A; C1D; MYT1L; PITX2; TAF1A; HMGB3; PMF1; ZNF492; RCOR1; BCOR; TBL1XR1; HSF2; ZBTB48; PBRM1; NEDD8; ZNF227; ZBTB11; MED14; ACTL6A; TCEB2; EED; MEIS1; RUVBL2; SAP18; RBBP7; PLAGL2; CCNC; KMT5A; CRY1; MTDH; NR1I2; CHAF1B; HOXB7; NR2F1; TSC22D2; TAF5; RAN; ZNF302; HOXA7; MED4; HMG20A; FOXJ3; EGR4; ZNF410; ZEB1; BRIP1; HIF1A; RB1; TBP; NFYB; PEX14; LZTS1; TFDP1; MBD4; BTAF1; ZBTB38; DMRT1; TAL1; ILF2; ERBB2; CEBPG; RBL1; EDF1; C1QBP; ZNF32; PIR; PSMC3IP; SMAD2; UBE2I; CERS6; CBFB; ENO1; TLE4; EYA1; ZNF711; ZIC1; CDK8; MED1; MSX1; TRIM24; CHD1; HNRNPD; COPS5; INSM1; MYCL; ZNF529; UBE2L3; BATF3; CEBPZ; ZNF22; PTTG1; HOXB6; KAT6A; EMX2; TOPORS; MEOX2; BMI1; CCDC59; PBX1; LPIN2; FOXD1; TAF1D; ZNF146; TCEA1; TCF4; CDK2; HTATIP2; ZNF516; CUX2; NFIB; ATF1; TOB1; ZBTB1; KDM5D; ISL1; BRD2; EGR1; PCGF2; PLAGL1; MYB; ETV5; RUVBL1; SMAD3; SALL1