Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59452	Plx-4720	GSE92742	NPC	Human	24h	10uM	EID0334

Response Information :

Types	Number	Response transcription factors
Up-regulation	196	FOSL1; NFKB2; BHLHE40; DAXX; CREB3L1; EDF1; RNF10; SSX1; NR0B1; MEF2C; EN2; STAT3; RNF4; PRDM1; SHOX2; ERF; EGR1; CENPB; SSBP3; NEUROD6; CBX4; TRIM16; REPIN1; CAMTA2; ZNF711; THAP11; CIZ1; MED21; AES; ELF3; TRIM32; MYF6; ZNF551; TAF1A; TAF6; ZNF335; EBF2; ZNF536; UBP1; PARP1; ZBTB16; HMG20B; ZNF84; ZNF384; GTF2F1; SSX3; MYT1L; MKL1; IRF3; FOXC1; TXNIP; JUNB; HOXC10; ZNF263; CBFA2T3; TRIM28; HABP4; ACTL6B; ZNF667; CBX6; ZSCAN5A; ESRRA; HSBP1; SFPQ; ZNF286A; EGR3; TGFB1I1; POU5F1B; SIX1; MDM2; TGFB1; HOXA1; PITX1; ZNF146; CHD1; ZNF257; MXD4; SPIB; HOXC6; NFYB; SIAH2; MYBL1; GFI1; ZSCAN32; MNDA; NEUROD1; UBE2B; ST18; HOXA3; NR4A3; RBM14; SOX10; NR4A2; HDAC4; ZNF444; PLAGL2; ARID3A; TFE3; ZBTB39; SCMH1; MAZ; SP3; RBFOX2; FOXD1; ITGB3BP; BCL11B; MAML1; ZZZ3; ZNF148; CBX7; ZNF274; HOXD3; HLX; NKRF; HOXB2; NR2F2; NR1H3; ZBTB38; ZNF468; ZNF329; ZNF768; NR4A1; SND1; MLXIP; THAP10; ZEB2; HOXB13; PAX6; CRYM; ZNF267; LITAF; ZNF394; ATN1; KAT2B; AIP; ARID1A; HMGA1; AFF1; ZMIZ2; POLR2A; DEAF1; CEBPB; REL; ESR1; YEATS2; DNAJC2; GATA6; IFI16; ARNTL2; ZNF91; ZNF426; ZNF423; CD3D; POU4F1; FOSB; MTA1; IRF4; CREB3L2; WT1; MYRF; EHF; TWIST1; LIN28A; USP21; TCF15; TRIM24; HOXB6; NKX2-2; DMTF1; HDAC9; RBPMS; TFAP2C; ZNF652; DNAJC1; IKBKAP; HOXB7; CUX2; LEF1; EGR2; SMARCA4; RUNX3; KLF10; ZNF430; MSX1; SMARCA2; KLF4; SATB2; ZKSCAN1; BRD2; KAT6A; CRK; KDM5D; TOX3; INSR; DRAP1; MAFB
Down-regulation	193	PUF60; DNMT1; KLF7; SMAD2; SALL2; TBPL1; ASCL1; HEY1; PBX3; SSBP2; RFXANK; CBFB; KAT2A; BRD8; MEOX1; ADNP2; CHD4; MAF; HEY2; HMBOX1; TBX2; PEX14; LDB1; BPTF; CREBZF; KLF6; TBX3; DACH1; SMARCA5; EYA1; RCOR3; TADA2A; ATF3; ECD; NR1I2; ZNF562; PRKDC; ING4; VGLL4; CDK8; KAT6B; TBP; JUND; ID4; YAF2; RFX5; ID3; SIX2; NKX2-1; PAX5; ZNF24; TRAF6; ZFY; ZNF34; KLF13; NCOA4; BTAF1; CDYL; FOXN2; HMGN3; THAP4; SMAD7; ZNF573; SP110; MED17; PLAG1; GFI1B; SOX5; FUBP1; TRIP6; ZNF432; C1D; TFAM; DDX5; PGR; SREBF1; RSF1; HOXA11; MNT; TRIM29; ARID5B; VEZF1; RAD21; TCF7L1; ZNF7; DPF2; TFDP1; XRCC6; MED14; SUPT4H1; CREB1; ARL2BP; ZNF3; HSF1; SMARCE1; KAT5; SMAD6; KLF9; EED; TCFL5; E2F3; PRPF6; ZBTB43; ILF2; NFKB1; TCF4; PPARGC1A; RBBP4; HBP1; RNF138; ING2; GTF3A; ZNF232; NAB1; HMGB1; BACH2; ZNF83; TRAK1; SAP18; CHD7; CNOT2; FOXO1; ISL1; ZBTB1; KLF11; MXI1; BRD7; TOB1; PMF1; RNF14; TDP2; KLF5; PATZ1; ENO1; TAL1; FOXA1; RB1; ARRB1; TAF1D; ZEB1; WWTR1; TRPS1; LOXL2; TLE4; CITED1; SP100; UBE2L3; PSMC3; FOXF1; ZNF576; IRF8; NR2F1; NFKBIA; NFATC3; NFATC4; ZFHX3; EMX2; CDK7; TCF21; PAXBP1; ZNF165; MED13; NFAT5; IRF9; SMAD3; ID1; LPIN2; FLNA; CREG1; MBD2; PEG3; ZFP36L2; PEX2; HIRA; ZNF22; CDK2; VPS72; BRD4; TCEA1; CAMTA1; TCEA2; NUP62; FOXG1; PBX1; MYB; HMGB2; KLF2; AEBP1; BHLHE41; SNAI2; NFKBIB; HOXA5; FOXO4