Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59438	Tak-715	GSE92742	NPC	Human	24h	10uM	EID0334

Response Information :

Types	Number	Response transcription factors
Up-regulation	86	FOSL1; CAPN15; KLF11; KLF4; INSM1; GFI1; CALR; ACTL6B; NFKBIB; AFF4; ZNF573; SSBP3; NEUROD1; PROX1; YWHAB; CHAF1B; ZNF248; AHR; TOX3; DEK; ZMYND8; PAX6; NEDD8; ZNF217; KAT2B; ST18; THAP10; RBL1; MED21; EN2; KLF10; IRF3; NR4A2; MYBL1; FOXF1; CBX3; PMS1; LIN28A; SAP30; ZNF415; LZTS1; PHF20; ZNF83; ZNF266; ZNF528; FUBP1; SUPT3H; HIPK3; ELK3; ZEB2; CAMTA1; MEIS1; NHLH2; SMARCB1; CD3D; VEZF1; DLX2; CBX5; RAD21; MYCN; ELF4; SMARCA2; CRY1; HHEX; SOX9; TOB1; HLTF; USP22; MKL2; RBPJ; FOXD1; TCF21; SERTAD2; TGFB1; PEG3; ZNF331; LOXL2; TSC22D2; HDAC9; IKBKAP; MAFB; BMI1; TRIM22; WT1; CITED2; KAT6A
Down-regulation	104	PUF60; SREBF1; NPM1; TRIP6; RBBP5; HEY2; TSHZ2; MAK; SIM2; PRMT2; FOXO1; SALL2; KLF13; RBBP8; LDB1; ZNF184; SMARCA1; BHLHE41; ZNF394; TRIM29; NAB1; ZHX2; MYB; C1QBP; CCNT1; RCOR1; TRIP4; RYBP; ZNF195; TCF3; PSPC1; SMAD2; SP140L; NLK; COPS2; BACH2; TBX3; CDK8; HOXB2; AR; MXI1; CITED1; RUNX1; ZBTB18; HBP1; IRF4; BBX; HTATIP2; MED6; PBX2; POU2F1; PLAG1; PRPF6; REPIN1; PNRC1; TCF7; PAX5; PSMC3; PLAGL1; ZBTB38; COPS5; JUND; PBXIP1; TCF7L2; ZNF467; ZFHX4; TFAP2C; CHD7; HMGB1; SMAD1; CEBPB; PTTG1; AGO2; CNOT6; TRPS1; NFATC1; TRIM16; EYA2; TFDP1; IRF9; ESR1; FOXC1; HIRA; CRK; CTR9; ZNF516; TP63; TBL1X; HOXC6; AEBP1; ID3; TCEA2; HOXC10; KLF2; EMX2; POU2AF1; SMAD7; HLX; TCEA1; HLF; BNC2; HMGB3; HOXA5; FOXO4