Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59435	Saracatinib	GSE92742	NPC	Human	24h	10uM	EID0334

Response Information :

Types	Number	Response transcription factors
Up-regulation	118	TADA3; NR1H2; HOXB13; ZNF282; SIRT2; HOXC8; NCOA3; KLF11; FOXA2; FOXF2; TBX21; GMNN; DDIT3; KLF15; ARID5B; MBD1; ZBTB43; HDAC9; SMARCD3; CBX4; LHX3; RBBP8; BRPF1; FOXK2; ZNF12; DEK; PIAS1; CBX7; ZNF665; HOXA11; PRDM1; HIRA; RARB; TRIB3; KLF13; ZNF669; TAF5L; REPIN1; KLF9; SPIB; RNF138; RAD21; CEBPD; TDP2; PBXIP1; CAPN15; ETS1; CNOT6; ZNF589; ZHX2; SPDEF; SOX10; CREBL2; USP21; JUN; CSDE1; TBX3; OLIG2; NFIC; HIF1A; NCOR1; KLF3; RUNX1; ID1; RERE; HIPK1; RBL2; TGFB1; PNRC1; IRF6; MED1; RNF6; YAP1; ZIC1; TRIM29; VEZF1; KAT2B; NR1D2; FOXA1; TP63; CBX6; THAP11; BBX; CITED1; SMAD3; BACH2; IL16; BRD4; CRYM; NR4A2; NR2F2; PSMC3; MYBL1; VPS72; IRF8; OSR2; PCGF2; DLX5; CDK7; RXRA; CEBPB; LEF1; ESR1; ID3; NKX3-1; ZNF91; KDM5D; HOXB6; PBX3; SNAI2; RORA; HMGB2; SOX9; ID4; CRK; TOX3; BASP1; KAT6A
Down-regulation	98	ZMIZ1; HOXC4; ZNF334; ERG; PHOX2B; EDF1; DNMT3B; TLE1; PLAG1; TFEC; EZH2; YEATS4; MEIS1; REST; ZNF492; ZNF226; EGR3; ZNF593; POU4F1; WDHD1; RCOR1; AFF1; TBP; EGR4; PMS1; LZTS1; SIM1; TAF1D; L3MBTL1; MYCN; DPF2; SOX3; PSMC3IP; PLAGL1; NR4A3; TBL1XR1; MITF; ZNF292; TSC22D2; CREM; HMGA2; NAB1; PSIP1; CCNA2; EMX2; HOXC6; GTF3A; PPARGC1A; ZNF711; ELK3; ZNF205; ZNF426; SMAD1; ENO1; RUNX3; POLR2A; MYC; FUBP1; ZNF410; NANOG; CARM1; MED23; TCF4; TCEB2; BTAF1; TAF10; ZFHX4; TRIP6; FOXN3; RB1; LIN28A; ZNF529; ZNF266; MED21; JUP; FLNA; MECOM; ATF1; NRIP1; TCEA2; SOX11; ZEB1; PBX1; MSX1; ERBB2; ZBTB1; BATF3; INSR; TGIF1; HMGB3; NUP62; TLE4; BMI1; CEBPZ; ZNF22; STAT5B; KLF4; CEBPA