Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59434	Motesanib	GSE92742	NPC	Human	24h	10uM	EID0334

Response Information :

Types	Number	Response transcription factors
Up-regulation	90	WNT4; PLAGL2; RARG; LHX3; CCNH; TP73; ZNF552; PROX1; ECD; TBX3; KLF15; LEF1; RUNX1; ZNF250; HOXA11; ARID5B; TRIB3; NFATC3; PURA; CBX4; MAF; TADA3; ZSCAN32; SIRT2; AEBP1; KLF13; HOXD10; ZFP36L2; CDX1; DDIT3; ZBTB16; MXI1; FOXA2; POU2AF1; IRF6; SOX17; CERS4; FOXF2; CEBPA; NFE2L3; CNOT2; NKX2-1; TLE2; ZNF467; FOXE1; HOXB13; PAX5; SRCAP; ATF4; NKRF; USP21; YBX3; BCL6; SP140L; KAT2B; KDM4C; TWIST1; RBM39; NFKBIA; GATA4; MECOM; ATN1; CEBPB; MLXIP; CDK2; FOXA1; TRIM29; ELF1; CD3D; ZFPM2; MAFB; TP63; ERBB4; RAD21; MED1; ESR1; ELF3; BRD2; IFI16; PRRX1; ETV1; RUVBL1; WT1; MEIS1; IKBKAP; TCEA2; SOX9; BTG1; KAT6A; CRK
Down-regulation	131	ZNF226; DNMT3B; LITAF; TAF10; KAT7; SNW1; CREB3L1; TRRAP; NANOG; MED7; RBM14; IRF2; EDF1; BBX; NRIP1; ADNP2; MYT1L; SPDEF; BCL10; VPS72; TEAD1; HDAC6; ZNF432; FOXJ3; MEF2A; FOSL2; TCF7L1; WDHD1; RBBP5; IRF4; BAZ2B; MAX; ZNF329; HDAC5; SP2; ORC2; MAGED1; ELF2; CREB1; EGR4; ID4; ZKSCAN7; TRIP6; TMF1; ETS1; SMAD4; TBL1X; BRD3; ZNF410; ZBTB11; PLAGL1; ZNF93; PLAG1; ZNF331; CENPF; LPIN2; TSC22D2; SIX2; ZFHX4; NR1H3; DPF2; ZNF184; PSMC3IP; HOXC6; HTATIP2; PREB; SOX11; ZNF587; NLK; SFPQ; CRY1; CTR9; KLF2; USP22; TFEC; BTAF1; MAFF; ATF1; STAT5A; TOX; EYA1; BAZ1A; BMI1; LZTS1; TSG101; RBPMS; SUPT4H1; JARID2; MYCL; SMARCA1; PITX1; ZNF22; HMGA1; CREM; RBBP4; EMX2; ZBTB1; CDK7; FLI1; ZBTB18; ZSCAN18; BIRC2; ZEB2; ZNF415; NCOA1; NUP62; PIR; BASP1; ZBTB20; TGIF1; TRIM16; PCGF2; SAP30; ZNF91; PBX1; TLE4; TCF4; IRF7; FOXG1; TRIM22; HMGB2; SMAD3; TOX3; PEG3; CTBP2; STAT5B; HLF; HMGB3; HOXA5; NFKBIB; FOXO4