Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59411	Safinamide	GSE92742	NPC	Human	24h	10uM	EID0333

Response Information :

Types	Number	Response transcription factors
Up-regulation	66	PHOX2B; STAT3; CRYM; BCL11A; BHLHE40; HMGA1; SATB1; REL; ISL1; PHIP; BTG1; ZBTB20; MKL2; DAXX; TRIM16; CREB3; MEIS2; HMGB3; LMCD1; NANOG; CUX2; GATA2; IRX5; MAGED1; HIRA; STAT4; AR; RLF; CTNNB1; EYA1; MYCL; ZNF532; PLAGL1; ETV1; ERBB4; TDP2; ZNF512B; FOXG1; SOX17; BCL11B; NCOA4; SFPQ; KLF10; KDM5D; ING2; MNDA; ELF3; YWHAB; SETD2; LITAF; TSC22D2; RCOR3; FOSB; BASP1; MEIS1; NKX2-1; MYBL1; ZNF652; TAF10; PITX1; ID4; IFI16; HOXC6; TCEA2; NKX3-1; PUF60
Down-regulation	72	ZMIZ1; TTF1; CHD4; MYB; MLXIP; INSM1; ZNF23; ZNF576; POLR3F; ZNF669; ST18; PAX6; PAXBP1; ZNF3; MNT; PCGF1; ZIC1; ZBED4; KLF7; TAL1; ZNF146; ZNF302; SMARCD3; KLF9; E2F8; PPARGC1A; VPS72; ZNF217; SAP30; SMAD5; NFE2L3; NFE2; ASCL1; CITED2; SKI; ERG; FOXO1; ZNF24; YBX3; HMGB1; NEUROD1; MXI1; ZBTB18; ZNF281; SMAD6; ZNF165; SAP18; ID3; TOX3; OLIG2; MYCN; CRK; ELK3; ATF3; ZNF124; FOXD1; HMG20B; MAFB; CERS6; GATA6; ID1; MYRF; ERBB2; CEBPG; ATF4; TRIM29; NR2F1; NUP62; ZKSCAN1; SMAD3; NFKBIB; EGR1