Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59390	Pirarubicin	GSE92742	NPC	Human	24h	10uM	EID0333

Response Information :

Types	Number	Response transcription factors
Up-regulation	302	FOS; DLX2; NR4A2; PRDM14; PDLIM1; THRB; CCNH; VDR; KLF9; ACTL6B; CBFA2T3; VGLL1; VPS72; DACH1; CDIP1; AR; LIN28A; STAT2; SNAI2; MECP2; SPDEF; SERTAD2; IRF9; NHLH1; CEBPD; CDK2; FOXA2; NR1H2; LHX6; KLF13; PRMT2; BNC1; AIRE; ZNF75D; ZNF154; KLF11; CRYM; LHX3; RFXANK; WNT4; SIX3; ELF4; NR3C1; ARNTL; CAMTA2; MBD1; HINFP; CSDE1; TSC22D3; MED25; PPARD; TFAP2A; ZNF264; ZIC3; BTG1; ZSCAN32; PRDM2; ZNF500; BCL11A; CCNE1; CCDC59; RAD21; ZNF394; ZHX2; ZBTB43; NFYA; ZNF335; TRPS1; HESX1; KLF15; ZNF586; NANOG; NR5A2; IKZF1; HOXA6; HOXD1; RARG; WT1; PSMC3; CSDC2; TUB; POLR3C; ZNF273; MYBL1; ZBTB17; CBFA2T2; ERBB4; ZNF235; GATA3; NEUROD6; CHD2; ZNF331; GATA6; ZNF611; TULP2; PAWR; ZNF556; HIC2; ATOH1; NFATC3; NAB2; SP100; SNAI1; ZNF350; DBP; NFRKB; CREB1; IFI16; CREG1; OSR2; MAP3K10; NR0B2; ST18; SOX17; FOXH1; GCM1; PRDM12; ZNF467; GTF2I; PAX6; CDX1; FUBP1; FOXE1; TULP3; ZNF215; RBBP8; TXNIP; DDIT3; CDX2; RXRG; PCGF1; OVOL1; ZNF816; MXD1; GATA1; HOXA4; ACTL6A; HNF1A; CREBZF; TAF5L; GFI1; HIPK2; SRY; VENTX; ZNF688; IRF6; CREBL2; JUNB; MEIS2; NPAS2; DLX5; HOXB5; NCOA2; EPAS1; KLF4; TBX21; HOXA1; TAF4B; ZNF711; NFYB; FOXJ2; CREB3L2; CITED2; CEBPB; EHF; SIRT7; LMCD1; OVOL2; ECD; HIPK1; JAK2; TGFB1; HOXA11; PBXIP1; ZNF141; TOB1; KDM4C; KAT2B; RNF14; ZNF770; SAP130; REL; TTF2; MXI1; SRCAP; RARB; MLXIP; CCNT1; HDAC9; PBX3; TAF9B; TOX4; EMX1; SOX13; INSM1; ZNF589; KLF3; TAF1; NEUROD1; SPIB; PIAS1; CNOT3; ARL2BP; ETS1; TP73; ZNF107; TCF7; FOXF2; USP16; TAF6; ZIM2; SSBP3; KLF10; HDAC5; NHLH2; PRDM1; ESRRG; POU2AF1; SOHLH2; CBX4; ZNF91; TSHZ2; MAFB; CREB3; NCOA3; TERF1; PGR; YAP1; YEATS4; ZNF12; ARID5B; HBP1; CD3D; TFAP2C; RBPMS; NEUROD2; FOXN3; IRF8; ZXDC; TRIB3; NR4A1; NFE2L2; SP140; TEAD4; MED14; ZFP36L2; SSX1; EZH1; ZFPM2; CALR; SOX3; SIX6; TRIP4; NCOA1; MNDA; ZNF665; NR1D2; ZNF180; ZNF654; URI1; PAX5; DMTF1; TRIM25; ZNF623; HLX; DNAJC2; HSF1; TWIST1; IRF7; FOSB; SOX9; TCF7L2; HOXD3; CEBPG; ZNF44; HOXA5; ZNF232; HLF; NFATC4; CBX6; BCL11B; RUNX1; TBX3; MYC; BNC2; BACH2; MYRF; EGR1; EN1; PRRX1; TP63; JUN; ZBTB16; SATB2; MEIS1; ID3; TRIM29; PEG3; RBL2; ESR1; ERG; BHLHE41
Down-regulation	347	BAZ2B; SMARCC1; CCNA2; HDAC2; HMGA1; HNRNPD; TBP; SOX4; CBX5; EDF1; MAGED1; SOX2; PBRM1; HSF2; USF2; TRIM28; RBBP4; CENPF; SNW1; ZNF292; PCBD1; RBM14; MAZ; MED24; HMGB3; BRD8; BRD3; RUVBL2; POLR2A; ARID4B; TCF12; PRKDC; E2F3; ASCL1; ZBTB1; CARHSP1; TP53; ZNF189; NCOR2; UBE2I; SIX1; SMARCA5; NONO; RXRB; ZKSCAN7; PCGF2; IRF2; BCLAF1; TRIM27; SFPQ; RAN; NCOR1; CTNNB1; ZNF358; HCFC1; SIX2; RLF; KAT7; JARID2; NUP62; CREB5; PATZ1; NRIP1; SREBF1; NELFB; HMGXB4; SSRP1; ZBED4; NFE2L1; APBB1; GABPB1; HDAC1; SMARCA4; ETV5; HDAC6; TLE1; ARID1A; EED; HMGA2; TCEB2; TAF10; GTF3A; ENO1; CDK8; MMS19; MED23; ERBB2; NPM1; SOX11; AES; TRAK1; YBX1; SMARCE1; HDAC7; EYA1; BMI1; ZBTB11; NFKBIA; CTBP1; EWSR1; ZMYM2; ZNF248; PARP1; SREBF2; ZNF226; PPRC1; HMG20B; DRAP1; CBFB; ZNF35; PIR; BAZ1A; TRRAP; AFF1; SALL1; TSC22D4; XRCC6; BTAF1; BRCA1; VGLL4; KDM4A; DDX54; ARID4A; CTCF; ZNF606; TCF3; ZNF302; BAZ1B; PTTG1; HOXB3; SMAD2; SAFB2; WDHD1; PSMC3IP; TCF15; TBL1XR1; HMG20A; ZMIZ2; NEDD8; SOX12; MDFI; ZNF329; TADA2A; ATF1; C1D; C1QBP; HMGB1; GMEB2; ZNF76; HDGF; ZNF146; TEAD1; PHF8; PA2G4; DEAF1; EZH2; ZNF432; BCL6; MGA; TCF20; CCNC; TCERG1; DNAJC1; NR2F2; SF1; ZBTB18; TRIM32; TFCP2; NFYC; MLX; RBPJ; RNF111; TCF4; ZNF135; ZNF574; MEF2D; BIRC2; BATF3; ATF4; ORC2; TAF1D; KAT5; ZNF148; SUV39H1; ETV4; RFX7; ETV1; ZNF443; GABPA; FOXJ3; NLK; KDM2A; REPIN1; ZFP64; ZNF646; ZBTB24; PRPF6; MYCBP; ZNF205; LPIN2; RBM39; USP22; POU3F2; ZFP30; BASP1; NCOA6; HSBP1; MED4; CHD3; PSPC1; TBL1X; KAT8; LDB1; CTR9; NCOA4; ZEB2; ELF2; MED7; CBX3; CNOT1; TFAM; TLE4; MED1; MAFF; SNIP1; DPF2; PBX2; TRIM16; TSC22D2; ZNF544; MXD3; ZNF528; PHF2; TBPL1; KAT6A; PMS1; CHD9; ZBTB20; LZTS1; ASH2L; FOXA1; ZNF529; NFIL3; CHD1; SETD2; THAP1; TCF25; KDM5D; ZNF24; KLF12; BRF2; GLI3; SAFB; PIAS3; WWTR1; ZBTB7A; AATF; MED13; MED16; SAP18; DDX5; DNMT3B; MTF1; PIAS2; RCOR1; MED6; SAP30; HOXB7; ZNF112; SCMH1; ZNF672; ZNF32; WHSC1; CARM1; ZNF692; GATAD2A; ZIC1; NKX3-1; CNOT2; PQBP1; HLTF; ZSCAN18; ZNF721; ZNF184; BCL3; NFIB; PREB; CDYL; ZFHX4; ATF7IP; HOXC6; DDX17; CNOT6; YWHAB; GTF2IRD1; ZNF410; IKBKAP; CRY1; SMAD1; MNAT1; ZNF587; REST; NFKB1; INSR; TOX3; SUB1; SMAD7; CTBP2; STAT6; ZNF217; EMX2; UBP1; SMAD6; ADNP; FOSL2; VEZF1; PITX2; MYCN; ITGB3BP; BATF; TGFB1I1; LOXL2; ZNF532; CERS6; PSIP1; PITX1; ING2; ETS2; MTF2; FOXD1; TCEA2; SCAND1; ZMYND8; AHR; HMBOX1; CRK; PLAGL1; MSX1; FOXG1; PUF60; ELK3; PHF20; NAB1; MEOX2; HEY1; FOSL1; NFKBIB